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Journal of Interventional Cardiac Electrophysiology

Published in:

01-01-2014 | REVIEWS

The infrahisian conduction system and endocavitary cardiac structures: relevance for the invasive electrophysiologist

Authors: Faisal F. Syed, Jo Jo Hai, Nirusha Lachman, Christopher V. DeSimone, Samuel J. Asirvatham

Published in: Journal of Interventional Cardiac Electrophysiology | Issue 1/2014

Excerpt

With the increasing acceptability and use of catheterization ablation for ventricular tachycardia, detailed anatomic studies have been done to improve the safety and efficacy for energy delivery in and around critical cardiac structures [1‐7]. More recently, ventricular fibrillation and certain forms of monomorphic ventricular tachycardia have required ablation in either the infrahisian conduction system or endocavitary cardiac structure, such as the papillary muscle, false tendons, and the right ventricular moderator band [8‐13]. In this review, we explain the critical details of structure and structure–function relations of the infrahisian tissue and the cardiac endocavitary structures. We approach the structures as a single unit with endocavitary structures routinely having a rich network of the distal His-Purkinje system. In addition, several commonly applied cardiac mapping maneuvers, including parahisian pacing and pacemapping, rely on understanding conduction tissue anatomy and active myocardium within the cavity for correct interpretation. Throughout the text are interspersed boxes that tabulate and summarize key anatomic pieces of information for the invasive electrophysiologist. …

Asirvatham, S. J. (2009). Correlative anatomy for the invasive electrophysiologist: outflow tract and supravalvar arrhythmia. [Review]. Journal of Cardiovascular Electrophysiology, 20(8), 955–968.PubMedCrossRef

Asirvatham, S. J. (2009). Correlative anatomy and electrophysiology for the interventional electrophysiologist: right atrial flutter. Journal of Cardiovascular Electrophysiology, 20(1), 113–122.PubMedCrossRef

Lachman, N., Syed, F. F., Habib, A., Kapa, S., Bisco, S. E., Venkatachalam, K. L., et al. (2011). Correlative anatomy for the electrophysiologist, part II: cardiac ganglia, phrenic nerve, coronary venous system. Journal of Cardiovascular Electrophysiology, 22(1), 104–110.PubMedCrossRef

Macedo, P. G., Kapa, S., Mears, J. A., Fratianni, A., & Asirvatham, S. J. (2010). Correlative anatomy for the electrophysiologist: ablation for atrial fibrillation. Part I: pulmonary vein ostia, superior vena cava, vein of Marshall. Journal of Cardiovascular Electrophysiology, 21(6), 721–730.PubMedCrossRef

Macedo, P. G., Kapa, S., Mears, J. A., Fratianni, A., & Asirvatham, S. J. (2010). Correlative anatomy for the electrophysiologist: ablation for atrial fibrillation. Part II: regional anatomy of the atria and relevance to damage of adjacent structures during AF ablation. Journal of Cardiovascular Electrophysiology, 21(7), 829–836.PubMed

Ho, S. Y. (2009). Structure and anatomy of the aortic root. [Research Support, Non-U.S. Gov’t Review]. European Journal of Echocardiography, 10(1), i3–i10.PubMedCrossRef

Gami, A. S., Noheria, A., Lachman, N., Edwards, W. D., Friedman, P. A., Talreja, D., et al. (2011). Anatomical correlates relevant to ablation above the semilunar valves for the cardiac electrophysiologist: a study of 603 hearts. Journal of Interventional Cardiac Electrophysiology, 30(1), 5–15.PubMedCrossRef

Haissaguerre, M., Shah, D. C., Jais, P., Shoda, M., Kautzner, J., Arentz, T., et al. (2002). Role of Purkinje conducting system in triggering of idiopathic ventricular fibrillation. Lancet, 359(9307), 677–678.PubMedCrossRef

Haissaguerre, M., Shoda, M., Jais, P., Nogami, A., Shah, D. C., Kautzner, J., et al. (2002). Mapping and ablation of idiopathic ventricular fibrillation. Circulation, 106(8), 962–967.PubMedCrossRef

10.

Abouezzeddine, O., Suleiman, M., Buescher, T., Kapa, S., Friedman, P. A., Jahangir, A., et al. (2010). Relevance of endocavitary structures in ablation procedures for ventricular tachycardia. Journal of Cardiovascular Electrophysiology, 21(3), 245–254.PubMedCrossRef

11.

Doppalapudi, H., Yamada, T., McElderry, H. T., Plumb, V. J., Epstein, A. E., & Kay, G. N. (2008). Ventricular tachycardia originating from the posterior papillary muscle in the left ventricle: a distinct clinical syndrome. Circulation. Arrhythmia and Electrophysiology, 1(1), 23–29.PubMedCrossRef

12.

Madhavan, M., & Asirvatham, S. J. (2010). The fourth dimension: endocavitary ventricular tachycardia. Circulation. Arrhythmia and Electrophysiology, 3(4), 302–304.PubMedCrossRef

13.

Srivathsan, K., Gami, A. S., Ackerman, M. J., & Asirvatham, S. J. (2007). Treatment of ventricular fibrillation in a patient with prior diagnosis of long QT syndrome: importance of precise electrophysiologic diagnosis to successfully ablate the trigger. Heart Rhythm, 4(8), 1090–1093.PubMedCrossRef

14.

Oosthoek, P. W., Viragh, S., Lamers, W. H., & Moorman, A. F. (1993). Immunohistochemical delineation of the conduction system. II: The atrioventricular node and Purkinje fibers. Circulation Research, 73(3), 482–491.PubMedCrossRef

15.

Ono, N., Yamaguchi, T., Ishikawa, H., Arakawa, M., Takahashi, N., Saikawa, T., et al. (2009). Morphological varieties of the Purkinje fiber network in mammalian hearts, as revealed by light and electron microscopy. Archives of Histology and Cytology, 72(3), 139–149.PubMedCrossRef

16.

Desplantez, T., Dupont, E., Severs, N. J., & Weingart, R. (2007). Gap junction channels and cardiac impulse propagation. Journal of Membrane Biology, 218(1–3), 13–28.PubMedCrossRef

17.

Nogami, A. (2011). Purkinje-related arrhythmias part ii: polymorphic ventricular tachycardia and ventricular fibrillation. Pacing and Clinical Electrophysiology, 34(8), 1034–1049.PubMedCrossRef

18.

Scheinman, M. M. (2009). Role of the His-Purkinje system in the genesis of cardiac arrhythmia. Heart Rhythm, 6(7), 1050–1058.PubMedCrossRef

19.

Nogami, A. (2011). Purkinje-related arrhythmias part I: monomorphic ventricular tachycardias. Pacing and Clinical Electrophysiology, 34(5), 624–650.PubMedCrossRef

20.

Waller, B. F., Gering, L. E., Branyas, N. A., & Slack, J. D. (1993). Anatomy, histology, and pathology of the cardiac conduction system: Part II. Clinical Cardiology, 16(4), 347–352.PubMedCrossRef

21.

Anderson, R. H., Becker, A. E., Brechenmacher, C., Davies, M. J., & Rossi, L. (1975). The human atrioventricular junctional area. A morphological study of the A-V node and bundle. European Journal of Cardiology, 3(1), 11–25.PubMed

22.

Massing, G. K., & James, T. N. (1976). Anatomical configuration of the His bundle and bundle branches in the human heart. [Research Support, U.S. Gov’t, P.H.S.]. Circulation, 53(4), 609–621.PubMedCrossRef

23.

James, T. N., Sherf, L., & Urthaler, F. (1974). Fine structure of the bundle-branches. British Heart Journal, 36(1), 1–18.PubMedCentralPubMedCrossRef

24.

Loukas, M., Klaassen, Z., Tubbs, R. S., Derderian, T., Paling, D., Chow, D., et al. (2010). Anatomical observations of the moderator band. Clinical Anatomy, 23(4), 443–450.PubMedCrossRef

25.

Widran, J., & Lev, M. (1951). The dissection of the atrioventricular node, bundle and bundle branches in the human heart. Circulation, 4(6), 863–867.PubMedCrossRef

26.

Demoulin, J. C., & Kulbertus, H. E. (1973). Left hemiblocks revisited from the histopathological viewpoint. American Heart Journal, 86(5), 712–713.PubMedCrossRef

27.

Kulbertus, H. E. (1975). Concept of left hemiblocks revisited. A histopathological and experimental study. Advances in Cardiology, 14, 126–135.PubMed

28.

Demoulin, J. C., & Kulbertus, H. E. (1972). Histopathological examination of concept of left hemiblock. British Heart Journal, 34(8), 807–814.PubMedCentralPubMedCrossRef

29.

Durrer, D., van Dam, R. T., Freud, G. E., Janse, M. J., Meijler, F. L., & Arzbaecher, R. C. (1970). Total excitation of the isolated human heart. Circulation, 41(6), 899–912.PubMedCrossRef

30.

Canale, E., Fujiwara, T., & Campbell, G. R. (1983). The demonstration of close nerve-Purkinje fibre contacts in false tendons of sheep heart. Cell and Tissue Research, 230(1), 105–111.PubMedCrossRef

31.

Tawara, S. (1906). Das reizleitungssystem des säugetierherzens. Eine anatomisch-histologishe studie über das atrioventikularbündel and die purinkeschen fäden. Jena: Gustav Fischer.

32.

Joyner, R. W., Ramza, B. M., & Tan, R. C. (1990). Effects of stimulation frequency on Purkinje-ventricular conduction. Annals of the New York Academy of Sciences, 591, 38–50.PubMedCrossRef

33.

Berenfeld, O., & Jalife, J. (1998). Purkinje-muscle reentry as a mechanism of polymorphic ventricular arrhythmias in a 3-dimensional model of the ventricles. Circulation Research, 82(10), 1063–1077.PubMedCrossRef

34.

Gilmour, R. F., Jr., Evans, J. J., & Zipes, D. P. (1984). Purkinje-muscle coupling and endocardial response to hyperkalemia, hypoxia, and acidosis. American Journal of Physiology, 247(2 Pt 2), H303–H311.PubMed

35.

Li, Z. Y., Wang, Y. H., Maldonado, C., & Kupersmith, J. (1994). Role of junctional zone cells between Purkinje fibres and ventricular muscle in arrhythmogenesis. Cardiovascular Research, 28(8), 1277–1284.PubMedCrossRef

36.

Saffitz, J. E., & Schuessler, R. B. (2000). Connexin-40, bundle-branch block, and propagation at the Purkinje-myocyte junction. Circulation Research, 87(10), 835–836.PubMedCrossRef

37.

Tranum-Jensen, J., Wilde, A. A., Vermeulen, J. T., & Janse, M. J. (1991). Morphology of electrophysiologically identified junctions between Purkinje fibers and ventricular muscle in rabbit and pig hearts. Circulation Research, 69(2), 429–437.PubMedCrossRef

38.

Anter, E., Buxton, A. E., Silverstein, J. R., & Josephson, M. E. (2013). Idiopathic ventricular fibrillation originating from the moderator band. Journal of Cardiovascular Electrophysiology, 24(1), 97–100.PubMedCrossRef

39.

Liu, X. K., Barrett, R., Packer, D. L., & Asirvatham, S. J. (2008). Successful management of recurrent ventricular tachycardia by electrical isolation of anterolateral papillary muscle. Heart Rhythm, 5(3), 479–482.PubMedCrossRef

40.

Yamada, T., Doppalapudi, H., McElderry, H. T., Okada, T., Murakami, Y., Inden, Y., et al. (2010). Electrocardiographic and electrophysiological characteristics in idiopathic ventricular arrhythmias originating from the papillary muscles in the left ventricle: relevance for catheter ablation. Circulation. Arrhythmia and Electrophysiology, 3(4), 324–331.PubMedCrossRef

41.

Crawford, T., Mueller, G., Good, E., Jongnarangsin, K., Chugh, A., Pelosi, F., Jr., et al. (2010). Ventricular arrhythmias originating from papillary muscles in the right ventricle. Heart Rhythm, 7(6), 725–730.PubMedCrossRef

42.

Sriram, C. S., Syed, F. F., Ferguson, M. E., Johnson, J. N., Enriquez-Sarano, M., Cetta, F., et al. (2013). Malignant Bileaflet Mitral Valve Prolapse Syndrome in Patients With Otherwise Idiopathic Out-of-Hospital Cardiac Arrest. Journal of the American College of Cardiology, 62(3), 222–230.PubMedCrossRef

43.

Victor, S., & Nayak, V. M. (1995). Variations in the papillary muscles of the normal mitral valve and their surgical relevance. Journal of Cardiac Surgery, 10(5), 597–607.PubMedCrossRef

44.

Nigri, G. R., Di Dio, L. J., & Baptista, C. A. (2001). Papillary muscles and tendinous cords of the right ventricle of the human heart: morphological characteristics. Surgical and Radiologic Anatomy, 23(1), 45–49.PubMedCrossRef

45.

Han, Y., Peters, D. C., Salton, C. J., Bzymek, D., Nezafat, R., Goddu, B., et al. (2008). Cardiovascular magnetic resonance characterization of mitral valve prolapse. JACC. Cardiovascular Imaging, 1(3), 294–303.PubMedCrossRef

46.

Myerburg, R. J., Nilsson, K., & Gelband, H. (1972). Physiology of canine intraventricular conduction and endocardial excitation. Circulation Research, 30(2), 217–243.PubMedCrossRef

47.

Veenstra, R. D., Joyner, R. W., & Rawling, D. A. (1984). Purkinje and ventricular activation sequences of canine papillary muscle. Effects of quinidine and calcium on the Purkinje-ventricular conduction delay. Circulation Research, 54(5), 500–515.PubMedCrossRef

48.

Abdulla, A. K., Frustaci, A., Martinez, J. E., Florio, R. A., Somerville, J., & Olsen, E. G. (1990). Echocardiography and pathology of left ventricular "false tendons". Chest, 98(1), 129–132.PubMedCrossRef

49.

Kervancioglu, M., Ozbag, D., Kervancioglu, P., Hatipoglu, E. S., Kilinc, M., Yilmaz, F., et al. (2003). Echocardiographic and morphologic examination of left ventricular false tendons in human and animal hearts. Clinical Anatomy, 16(5), 389–395.PubMedCrossRef

50.

Loukas, M., Wartmann, C. T., Tubbs, R. S., Apaydin, N., Louis, R. G., Jr., Black, B., et al. (2008). Right ventricular false tendons, a cadaveric approach. Surgical and Radiologic Anatomy, 30(4), 317–322.PubMedCrossRef

51.

Luetmer, P. H., Edwards, W. D., Seward, J. B., & Tajik, A. J. (1986). Incidence and distribution of left ventricular false tendons: an autopsy study of 483 normal human hearts. Journal of the American College of Cardiology, 8(1), 179–183.PubMedCrossRef

52.

Suwa, M., Hirota, Y., Kaku, K., Yoneda, Y., Nakayama, A., Kawamura, K., et al. (1988). Prevalence of the coexistence of left ventricular false tendons and premature ventricular complexes in apparently healthy subjects: a prospective study in the general population. Journal of the American College of Cardiology, 12(4), 910–914.PubMedCrossRef

53.

Suwa, M., Hirota, Y., Nagao, H., Kino, M., & Kawamura, K. (1984). Incidence of the coexistence of left ventricular false tendons and premature ventricular contractions in apparently healthy subjects. Circulation, 70(5), 793–798.PubMedCrossRef

54.

Kuznetsov, V. A., Kuznetsova, N. I., Loginov, O. L., Osokin, S. A., Shalaev, S. V., & Gizatulina, T. P. (1992). Relationship between ventricular arrhythmias and left ventricular false tendons in acute myocardial infarction. Revista Portuguesa de Cardiologia, 11(12), 1125–1131.PubMed

55.

Thakur, R. K., Klein, G. J., Sivaram, C. A., Zardini, M., Schleinkofer, D. E., Nakagawa, H., et al. (1996). Anatomic substrate for idiopathic left ventricular tachycardia. Circulation, 93(3), 497–501.PubMedCrossRef

56.

Akhtar, M., Gilbert, C., Wolf, F. G., & Schmidt, D. H. (1978). Reentry within the His-Purkinje system. Elucidation of reentrant circuit using right bundle branch and His bundle recordings. Circulation, 58(2), 295–304.PubMedCrossRef

57.

Bogun, F., Good, E., Reich, S., Elmouchi, D., Igic, P., Tschopp, D., et al. (2006). Role of Purkinje fibers in post-infarction ventricular tachycardia. Journal of the American College of Cardiology, 48(12), 2500–2507.PubMedCrossRef

58.

Hayashi, M., Kobayashi, Y., Iwasaki, Y. K., Morita, N., Miyauchi, Y., Kato, T., et al. (2006). Novel mechanism of postinfarction ventricular tachycardia originating in surviving left posterior Purkinje fibers. Heart Rhythm, 3(8), 908–918.PubMedCrossRef

59.

Dun, W., & Boyden, P. A. (2008). The Purkinje cell; 2008 style. Journal of Molecular and Cellular Cardiology, 45(5), 617–624.PubMedCrossRef

60.

Peters, N. S., & Wit, A. L. (1998). Myocardial architecture and ventricular arrhythmogenesis. [Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S. Review]. Circulation, 97(17), 1746–1754.PubMedCrossRef

61.

Xie, Y., Sato, D., Garfinkel, A., Qu, Z., & Weiss, J. N. (2010). So little source, so much sink: requirements for afterdepolarizations to propagate in tissue. Biophysical Journal, 99(5), 1408–1415.PubMedCentralPubMedCrossRef

62.

Szumowski, L., Sanders, P., Walczak, F., Hocini, M., Jais, P., Kepski, R., et al. (2004). Mapping and ablation of polymorphic ventricular tachycardia after myocardial infarction. Journal of the American College of Cardiology, 44(8), 1700–1706.PubMedCrossRef

63.

Tabereaux, P. B., Walcott, G. P., Rogers, J. M., Kim, J., Dosdall, D. J., Robertson, P. G., et al. (2007). Activation patterns of Purkinje fibers during long-duration ventricular fibrillation in an isolated canine heart model. Circulation, 116(10), 1113–1119.PubMedCrossRef

64.

Dosdall, D. J., Cheng, K. A., Huang, J., Allison, J. S., Allred, J. D., Smith, W. M., et al. (2007). Transmural and endocardial Purkinje activation in pigs before local myocardial activation after defibrillation shocks. Heart Rhythm, 4(6), 758–765.PubMedCentralPubMedCrossRef

65.

Janse, M. J., van Capelle, F. J., Morsink, H., Kleber, A. G., Wilms-Schopman, F., Cardinal, R., et al. (1980). Flow of "injury" current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts. Evidence for two different arrhythmogenic mechanisms. Circulation Research, 47(2), 151–165.PubMedCrossRef

66.

Janse, M. J., Kleber, A. G., Capucci, A., Coronel, R., & Wilms-Schopman, F. (1986). Electrophysiological basis for arrhythmias caused by acute ischemia. Role of the subendocardium. Journal of Molecular and Cellular Cardiology, 18(4), 339–355.PubMedCrossRef

67.

Damiano, R. J., Jr., Smith, P. K., Tripp, H. F., Jr., Asano, T., Small, K. W., Lowe, J. E., et al. (1986). The effect of chemical ablation of the endocardium on ventricular fibrillation threshold. Circulation, 74(3), 645–652.PubMedCrossRef

68.

Haissaguerre, M., Extramiana, F., Hocini, M., Cauchemez, B., Jais, P., Cabrera, J. A., et al. (2003). Mapping and ablation of ventricular fibrillation associated with long-QT and Brugada syndromes. Circulation, 108(8), 925–928.PubMedCrossRef

69.

Cerrone, M., Noujaim, S. F., Tolkacheva, E. G., Talkachou, A., O’Connell, R., Berenfeld, O., et al. (2007). Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia. Circulation Research, 101(10), 1039–1048.PubMedCentralPubMedCrossRef

70.

Harris, B. S., Baicu, C. F., Haghshenas, N., Kasiganesan, H., Scholz, D., Rackley, M. S., et al. (2012). Remodeling of the peripheral cardiac conduction system in response to pressure overload. American Journal of Physiology - Heart and Circulatory Physiology, 302(8), H1712–H1725.PubMedCrossRef

71.

Armiger, L. C., Urthaler, F., & James, T. N. (1979). Morphological changes in the right ventricular septomarginal trabecula (false tendon) during maturation and ageing in the dog heart. Journal of Anatomy, 129(Pt 4), 805–817.PubMed

72.

Coghlan, H. C., Coghlan, A. R., Buckberg, G. D., & Cox, J. L. (2006). ‘The electrical spiral of the heart’: its role in the helical continuum. The hypothesis of the anisotropic conducting matrix. European Journal of Cardio-Thoracic Surgery, 29(Suppl 1), S178–S187.PubMedCrossRef

73.

Forsgren, S. (1987). Marked sympathetic innervation in the regions of the bundle branches shown by catecholamine histofluorescence. Journal of Molecular and Cellular Cardiology, 19(6), 555–568.PubMedCrossRef

74.

Forsgren, S. (1988). The distribution of terminal sympathetic nerve fibers in bundle branches and false tendons of the bovine heart. An immunohistochemical and catecholamine histofluorescence study. Anatomy and Embryology (Berlin), 177(5), 437–443.CrossRef

75.

Fenoglio, J. J., Jr., Albala, A., Silva, F. G., Friedman, P. L., & Wit, A. L. (1976). Structural basis of ventricular arrhythmias in human myocardial infarction: a hypothesis. Human Pathology, 7(5), 547–563.PubMedCrossRef

76.

Pak, H. N., Kim, Y. H., Lim, H. E., Chou, C. C., Miyauchi, Y., Fang, Y. H., et al. (2006). Role of the posterior papillary muscle and purkinje potentials in the mechanism of ventricular fibrillation in open chest dogs and Swine: effects of catheter ablation. Journal of Cardiovascular Electrophysiology, 17(7), 777–783.PubMedCrossRef

77.

Guo, L. S., Zhou, X., Li, Y. H., Cai, J., Wei, D. M., Shi, L., et al. (2010). Alcohol ablation at the posterior papillary muscle prevents ventricular fibrillation in swine without affecting mitral valve function. Europace, 12(12), 1781–1786.PubMedCrossRef

78.

Kim, Y. H., Xie, F., Yashima, M., Wu, T. J., Valderrabano, M., Lee, M. H., et al. (1999). Role of papillary muscle in the generation and maintenance of reentry during ventricular tachycardia and fibrillation in isolated swine right ventricle. [In Vitro Research Support, Non-U.S. Gov’t Research Support, U.S. Gov’t, P.H.S.]. Circulation, 100(13), 1450–1459.PubMedCrossRef

79.

Yokokawa, M., Good, E., Desjardins, B., Crawford, T., Jongnarangsin, K., Chugh, A., et al. (2010). Predictors of successful catheter ablation of ventricular arrhythmias arising from the papillary muscles. Heart Rhythm, 7(11), 1654–1659.PubMedCentralPubMedCrossRef

80.

Park, J., Kim, Y. H., Hwang, C., & Pak, H. N. (2012). Electroanatomical characteristics of idiopathic left ventricular tachycardia and optimal ablation target during sinus rhythm: significance of preferential conduction through Purkinje fibers. Yonsei Medical Journal, 53(2), 279–288.PubMedCentralPubMedCrossRef

81.

Nakahara, S., Toratani, N., & Takayanagi, K. (2012). Catheter ablation of ventricular tachycardia originating from the left posterior papillary muscle guided by the shadow of a multipolar catheter. Indian Pacing and Electrophysiol Journal, 12(4), 186–189.

82.

Gonzalez, R. P., Scheinman, M. M., Lesh, M. D., Helmy, I., Torres, V., & Van Hare, G. F. (1994). Clinical and electrophysiologic spectrum of fascicular tachycardias. American Heart Journal, 128(1), 147–156.PubMedCrossRef

83.

Del Carpio Munoz, F., Buescher, T. L., & Asirvatham, S. J. (2011). Teaching points with 3-dimensional mapping of cardiac arrhythmias: teaching point 3: when early is not early. Circulation. Arrhythmia and Electrophysiology, 4(2), e11–e14.PubMedCrossRef

84.

Good, E., Desjardins, B., Jongnarangsin, K., Oral, H., Chugh, A., Ebinger, M., et al. (2008). Ventricular arrhythmias originating from a papillary muscle in patients without prior infarction: a comparison with fascicular arrhythmias. Heart Rhythm, 5(11), 1530–1537.PubMedCrossRef

85.

Tawara, S. (1906). Das Reizleitungssystem des Säugetierherzens. Eine anatomisch-histologische Studie über das Atrioventrikularbündel und die Purkinjeschen Fäden. Jena: Gustav Fischer.

86.

Pallante, B. A., Giovannone, S., Fang-Yu, L., Zhang, J., Liu, N., Kang, G., et al. (2010). Contactin-2 expression in the cardiac Purkinje fiber network. Circulation. Arrhythmia and Electrophysiology, 3(2), 186–194.PubMedCentralPubMedCrossRef

87.

Atkinson, A., Inada, S., Li, J., Tellez, J. O., Yanni, J., Sleiman, R., et al. (2011). Anatomical and molecular mapping of the left and right ventricular His-Purkinje conduction networks. Journal of Molecular and Cellular Cardiology, 51(5), 689–701.PubMedCrossRef

88.

Sebastian, R., Zimmerman, V., Romero, D., Sanchez-Quintana, D., & Frangi, A. F. (2013). Characterization and modeling of the peripheral cardiac conduction system. IEEE Transactions on Medical Imaging, 32(1), 45–55.PubMedCrossRef

89.

Stephenson, R. S., Boyett, M. R., Hart, G., Nikolaidou, T., Cai, X., Corno, A. F., et al. (2012). Contrast enhanced micro-computed tomography resolves the 3-dimensional morphology of the cardiac conduction system in mammalian hearts. PLoS One, 7(4), e35299.PubMedCentralPubMedCrossRef

90.

Gulyaeva, A. S., & Roshchevskaya, I. M. (2012). Morphology of moderator bands (septomarginal trabecula) in porcine heart ventricles. Anatomia Histologia and Embryologia, 41(5), 326–332.CrossRef

Title: The infrahisian conduction system and endocavitary cardiac structures: relevance for the invasive electrophysiologist
Authors: Faisal F. Syed
Jo Jo Hai
Nirusha Lachman
Christopher V. DeSimone
Samuel J. Asirvatham
Publication date: 01-01-2014
Publisher: Springer US
Published in: Journal of Interventional Cardiac Electrophysiology / Issue 1/2014
Print ISSN: 1383-875X
Electronic ISSN: 1572-8595
DOI: https://doi.org/10.1007/s10840-013-9858-7

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