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Journal of Assisted Reproduction and Genetics
Published in: Journal of Assisted Reproduction and Genetics 8/2009

01-08-2009 | Assisted Reproduction

Top quality embryos at day 2: a prerequisite for single blastocyst transfer? An observational cohort study in women under 36

Authors: Fabrice Guerif, Malak Lemseffer, Milène Blanchard, Dominique Royere

Published in: Journal of Assisted Reproduction and Genetics | Issue 8/2009

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Abstract

Purpose

While extended culture has been considerably improved, some questions remain regarding the application of Single Blastocyst Transfer (SBT).

Methods

An observational cohort study was undertaken with 456 women under 36 years old and assigned to SBT on a voluntary basis. The main outcome was the cumulative delivery rate per couple according to the number of Top Quality Embryos (TQE) on day 2 (Group 1= ≥2 TQE, Group 2= 1 TQE and Group 3= 0 TQE).

Results

Rate of transfer and mean number of frozen blastocyts were higher in Group 1 compared to Group 3. As a consequence, the cumulative delivery rate per couple was higher in Group 1 (47.9%) compared to Group 3 (34.9%).

Conclusions

Single blastocyst transfer combining fresh and frozen cycles, might be a worthwhile strategy irrespective of embryo quality on day 2 providing good delivery rates while keeping the rate of multiple deliveries low.
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Metadata
Title
Top quality embryos at day 2: a prerequisite for single blastocyst transfer? An observational cohort study in women under 36
Authors
Fabrice Guerif
Malak Lemseffer
Milène Blanchard
Dominique Royere
Publication date
01-08-2009
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 8/2009
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-009-9345-3

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