Published in:
01-05-2016
Severe pulmonary arterial hypertension: stratification of medical therapies, mechanical support, and lung transplantation
Authors:
Sonja Darrell Bartolome, Fernando Torres
Published in:
Heart Failure Reviews
|
Issue 3/2016
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Abstract
Severe pulmonary hypertension is recognized by focusing on the clinical signs and tests that demonstrate decompensated right ventricular failure or, in the worst-case scenario, shock. An aggressive treatment regimen including a prostacyclin infusion is required for these patients. Once admitted to the hospital, or the ICU for decompensated right ventricular failure, the short- and long-term outcomes for PAH patients are poor. For those who are candidates, urgent lung transplantation, or extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation may be rescue therapy.