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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 4/2022

01-04-2022 | Infliximab | Multicenter Seminars: IBD (MUSE: IBD)

Serving Up a Mediterranean Remission in Severe Ulcerative Colitis

Authors: Gila Sasson, Caitlin Hosmer Kirby, Matthew J. Hamilton, Rachel W. Winter

Published in: Digestive Diseases and Sciences | Issue 4/2022

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Excerpt

A 44-year-old male with longstanding ulcerative pancolitis was initially managed with mesalamine and subsequently treated with infliximab and 6-mercaptopurine. Over the years, infliximab trough levels and thiopurine metabolites were consistently subtherapeutic or undetectable, without evidence of anti-infliximab antibodies. His medical therapy was not changed per his preference. …
Literature
1.
WHO. Guideline: Sugars intake for adults and children. Geneva: World Health Organization; 2015.
2.
Ananthakrishnan AN, Khalili H, Konijeti GG et al. A prospective study of long-term intake of dietary fiber and risk of Crohn’s disease and ulcerative colitis. Gastroenterology. 2013;145:970–977.CrossRef
3.
Ananthakrishnan AN, Khalili H, Konijeti GG et al. Long-term intake of dietary fat and risk of ulcerative colitis and Crohn’s disease. Gut. 2014;63:776–784.CrossRef
4.
IBD in EPIC Study Investigators, Tjonneland A, Overvad K et al. Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study. Gut. 2009;58:1606–1611.CrossRef
5.
Chan SS, Luben R, Olsen A et al. Association between high dietary intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn’s disease. Aliment Pharmacol Ther. 2014;39:834–842.CrossRef
6.
Opstelten JL, Leenders M, Dik VK et al. Dairy products, dietary calcium, and risk of inflammatory bowel disease: results from a European Prospective Cohort Investigation. Inflamm Bowel Dis. 2016;22:1403–1411.CrossRef
7.
Shivashankar R, Lewis JD. The role of diet in inflammatory bowel disease. Curr Gastroenterol Rep. 2017;19:22.CrossRef
8.
Haskey N, Gibson DL. An examination of diet for the maintenance of remission in inflammatory bowel disease. Nutrients. 2017;9:259.CrossRef
9.
Jowett SL, Seal CJ, Pearce MS et al. Influence of dietary factors on the clinical course of ulcerative colitis: a prospective cohort study. Gut. 2004;53:1479–1484.CrossRef
10.
Manzel A, Muller DN, Hafler DA et al. Role of “Western diet” in inflammatory autoimmune diseases. Curr Allergy Asthma Rep. 2014;14:404.CrossRef
11.
Racine A, Carbonnel F, Chan SSM et al. Dietary patterns and risk of inflammatory bowel disease in Europe: results from the EPIC study. Inflamm Bowel Dis. 2016;22:345–354.CrossRef
12.
De Filippo C, Cavalieri D, Di Paola M et al. Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proc Natl Acad Sci U S A 2010;107:14691–14696.CrossRef
13.
Moszak M, Szulińska M, Bogdański P. You are what you eat-the relationship between diet, microbiota, and metabolic disorders—a review. Nutrients 2020;12:1096.CrossRef
14.
Martinez-Medina M, Denizot J, Dreux N et al. Western diet induces dysbiosis with increased E. coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation. Gut. 2014;63:116–124.CrossRef
15.
Wilck N, Matus MG, Kearney SM et al. Salt-responsive gut commensal modulates TH17 axis and disease. Nature. 2017;551:585–589.CrossRef
16.
D’Souza S, Levy E, Mack D et al. Dietary patterns and risk for Crohn’s disease in children. Inflamm Bowel Dis. 2008;14:367–373.CrossRef
17.
Meslier V, Laiola M, Roager HM et al. Mediterranean diet intervention in overweight and obese subjects lowers plasma cholesterol and causes changes in the gut microbiome and metabolome independently of energy intake. Gut. 2020;69:1258–1268.CrossRef
18.
Ghosh TS, Rampelli S, Jeffery IB et al. Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries. Gut. 2020;69:1218–1228.CrossRef
19.
Merra G, Noce A, Marrone G et al. Influence of mediterranean diet on human gut microbiota. Nutrients. 2020;13:7.CrossRef
20.
Borrelli O, Cordischi L, Cirulli M et al. Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn’s disease: a randomized controlled open-label trial. Clin Gastroenterol Hepatol. 2006;4:744–753.CrossRef
21.
Cohen SA, Gold BD, Oliva S et al. Clinical and mucosal improvement with specific carbohydrate diet in pediatric Crohn disease. Pediatr Gastroenterol Nutr. 2014;59:516–521.CrossRef
22.
Chicco F, Magrì S, Cingolani A et al. Multidimensional impact of mediterranean diet on IBD patients. Inflamm Bowel Dis. 2021;27:1–9.CrossRef
23.
Holt DQ, Strauss BJ, Moore GT. Patients with inflammatory bowel disease and their treating clinicians have different views regarding diet. J Hum Nutr Diet. 2017;30:66–72.CrossRef
24.
Tinsley A, Ehrlich OG, Hwang C et al. Knowledge, attitudes, and beliefs regarding the role of nutrition in IBD among patients and providers. Inflamm Bowel Dis. 2016;22:2474–2481.CrossRef
25.
Gkikas K, Gerasimidis K, Milling S et al. Dietary strategies for maintenance of clinical remission in inflammatory bowel diseases: are we there yet? Nutrients 2020;12:2018.CrossRef
Metadata
Title
Serving Up a Mediterranean Remission in Severe Ulcerative Colitis
Authors
Gila Sasson
Caitlin Hosmer Kirby
Matthew J. Hamilton
Rachel W. Winter
Publication date
01-04-2022
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 4/2022
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-022-07447-2

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