Small Intestinal Bacterial Overgrowth and Coronary Artery Disease: What Is in the CArDs?

Excerpt

Small intestinal bacterial overgrowth (SIBO) manifests with a variety of gastrointestinal symptoms, including bloating, flatulence, abdominal pain, nausea, dyspepsia, fatigue, diarrhea, and constipation [1]. SIBO has been implicated as a cause of hepatic encephalopathy and of d-lactic acidosis in patients with short bowel syndrome [2, 3]. Moreover, SIBO is associated with a variety of conditions outside of the gastrointestinal system, including rosacea [4], restless legs syndrome [5], interstitial cystitis [6], and chronic prostatitis [7], and correlates with the level of somatic pain in fibromyalgia [8]. Along these lines, recent studies have reported a link between SIBO and cardiovascular disease. …