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Published in: Breast Cancer Research and Treatment 3/2020

01-06-2020 | Breast Cancer | Letter to the Editor

Anti-HER2 therapy for metastatic breast cancer in low- and middle-income countries: bridging the gap between clinical trials and real life

Authors: Leonardo Ribeiro Soares, Victor Domingos Lisita Rosa, Ruffo Freitas-Junior

Published in: Breast Cancer Research and Treatment | Issue 3/2020

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Excerpt

We read with great interest the work of Gong et al. [1], which addressed the differences in clinical outcomes in women with HER2-positive metastatic breast cancer (MBC) conducted in clinical trials and in real life. In the population-based cohort, the overall survival observed in populations treated with trastuzumab/pertuzumab (39.2 months) and T-DM1 (15.4 months) was lower than that observed in the respective pivotal clinical trials (56.4 and 30.9 months, respectively). …
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Metadata
Title
Anti-HER2 therapy for metastatic breast cancer in low- and middle-income countries: bridging the gap between clinical trials and real life
Authors
Leonardo Ribeiro Soares
Victor Domingos Lisita Rosa
Ruffo Freitas-Junior
Publication date
01-06-2020
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 3/2020
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-020-05659-6

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