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Breast Cancer Research and Treatment
Published in: Breast Cancer Research and Treatment 3/2012

01-12-2012 | Clinical Trial

Knowledge and perceptions of familial and genetic risks for breast cancer risk in adolescent girls

Authors: Angela R. Bradbury, Linda Patrick-Miller, Brian L. Egleston, Lisa A. Schwartz, Colleen B. Sands, Rebecca Shorter, Cynthia W. Moore, Lisa Tuchman, Paula Rauch, Shreya Malhotra, Brianne Rowan, Stephanie Van Decker, Helen Schmidheiser, Lisa Bealin, Patrick Sicilia, Mary B. Daly

Published in: Breast Cancer Research and Treatment | Issue 3/2012

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Abstract

Evidence suggests early events might modify adult breast cancer risk and many adolescents learn of familial and genetic risks for breast cancer. Little is known about how adolescent girls understand and respond to breast cancer risk. Semi-structured interviews with 11–19 year-old girls at high-risk and population-risk for breast cancer evaluated knowledge and perceptions of breast cancer risk and risk modification. Framework analysis and descriptive statistics were utilized to analyze open-ended responses. Risk group and age differences were evaluated by Fisher’s exact and McNemar’s tests. Fifty-four girls (86 % of invited), 35 high-risk (65 %), and 19 population-risk (35 %) completed interviews. The most frequently reported risk for breast cancer was family history/hereditary predisposition (66 %). Only 17 % of girls were aware of BRCA1/2 genes. The majority (76 %) of high-risk girls perceive themselves to be at increased risk for breast cancer, compared to 22 % of population-risk girls (p = 0.001). Half of girls reported that women can get breast cancer before 20-years-old. The majority believe there are things women (70 %) and girls (67 %) can do to prevent breast cancer. Mother was the most frequently reported source of information for breast cancer among both high-risk (97 %) and population-risk (89 %) girls. In this study, many high-risk girls perceive themselves to be at increased risk for breast cancer, and many girls believe that breast cancer can occur in teens. Yet, most girls believe there are things women and girls can do to prevent breast cancer. Research evaluating the impact of awareness and perceptions of breast cancer risk on psychosocial, health, and risk behaviors is needed to develop strategies to optimize responses to cancer risk.
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Metadata
Title
Knowledge and perceptions of familial and genetic risks for breast cancer risk in adolescent girls
Authors
Angela R. Bradbury
Linda Patrick-Miller
Brian L. Egleston
Lisa A. Schwartz
Colleen B. Sands
Rebecca Shorter
Cynthia W. Moore
Lisa Tuchman
Paula Rauch
Shreya Malhotra
Brianne Rowan
Stephanie Van Decker
Helen Schmidheiser
Lisa Bealin
Patrick Sicilia
Mary B. Daly
Publication date
01-12-2012
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 3/2012
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-012-2254-7

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