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AIDS and Behavior
Published in: AIDS and Behavior 5/2018

01-05-2018 | Original Paper

A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults

Authors: Catherine A. Dufour, María J. Marquine, Pariya L. Fazeli, Anya Umlauf, Brook L. Henry, Zvinka Zlatar, Jessica L. Montoya, Ronald J. Ellis, Igor Grant, David J. Moore, HIV Neurobehavioral Research Program Group

Published in: AIDS and Behavior | Issue 5/2018

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Abstract

Higher levels of physical activity (PA) have been linked to better neurocognitive functioning in many populations. The current study examines the longitudinal association between PA and neurocognitive functioning among HIV-infected and HIV-uninfected persons. Community-dwelling adults (N = 291) self-reported level of PA and completed a comprehensive neuropsychological battery at two to four study visits (Mean follow-up time = 2.6 years). Participants were divided into three PA groups: “No PA” (no PA at any visit), “consistent PA” (PA at ≥50% of visits), and “inconsistent PA” (PA < 50% of visits). A mixed effect model, adjusting for significant covariates showed that all PA groups had statistically significant, yet modest, neurocognitive decline over time; and, the consistent PA group began with, and maintained, significantly better neurocognitive function compared to the other two PA groups. This effect was evident among both HIV-uninfected and HIV-infected persons, despite the fact that HIV-infected persons showed lower baseline neurocognitive function. PA is a modifiable lifestyle behavior that may help to protect against neurocognitive impairment regardless of HIV status, however, given the proportion of HIV-infected individuals who evidence neurocognitive difficulties, a focus on increasing PA seems warranted.
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Metadata
Title
A Longitudinal Analysis of the Impact of Physical Activity on Neurocognitive Functioning Among HIV-Infected Adults
Authors
Catherine A. Dufour
María J. Marquine
Pariya L. Fazeli
Anya Umlauf
Brook L. Henry
Zvinka Zlatar
Jessica L. Montoya
Ronald J. Ellis
Igor Grant
David J. Moore
HIV Neurobehavioral Research Program Group
Publication date
01-05-2018
Publisher
Springer US
Published in
AIDS and Behavior / Issue 5/2018
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-016-1643-z

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