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01-06-2017 | Original Paper

Use of Western Neuropsychological Test Battery in Detecting HIV-Associated Neurocognitive Disorders (HAND) in Zambia

Authors: Norma Kabuba, J. Anitha Menon, Donald R. Franklin Jr., Robert K. Heaton, Knut A. Hestad

Published in: AIDS and Behavior | Issue 6/2017

Abstract

This is a study of neuroAIDS in sub-Saharan Africa, involving 266 Zambian adults infected with the human immunodeficiency virus (HIV), clade C. All HIV+ participants were receiving combination antiretroviral therapy (CART), and were administered a comprehensive neuropsychological (NP) test battery covering seven ability domains that are frequently affected by neuroAIDS. The battery was developed in the U.S. but has been validated in other international settings and has demographically-corrected normative standards based upon 324 healthy Zambian adults. Compared to the healthy Zambian controls, the HIV+ sample performed worse on the NP battery with a medium effect size (Cohen’s d = 0.64). 34.6 % of the HIV+ individuals had global NP impairment and met criteria for HIV associated neurocognitive disorder (HAND). The results indicate that the Western-developed NP test battery is appropriate for use in Zambia and can serve as a viable HIV and AIDS management tool.

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Title: Use of Western Neuropsychological Test Battery in Detecting HIV-Associated Neurocognitive Disorders (HAND) in Zambia
Authors: Norma Kabuba
J. Anitha Menon
Donald R. Franklin Jr.
Robert K. Heaton
Knut A. Hestad
Publication date: 01-06-2017
Publisher: Springer US
Published in: AIDS and Behavior / Issue 6/2017
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI: https://doi.org/10.1007/s10461-016-1443-5

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