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Published in: AIDS and Behavior 6/2010

01-12-2010 | Original Paper

Challenges in Using Mobile Phones for Collection of Antiretroviral Therapy Adherence Data in a Resource-Limited Setting

Authors: Jessica E. Haberer, Julius Kiwanuka, Denis Nansera, Ira B. Wilson, David R. Bangsberg

Published in: AIDS and Behavior | Issue 6/2010

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Abstract

Frequent antiretroviral therapy adherence monitoring could detect incomplete adherence before viral rebound develops and thus potentially prevent treatment failure. Mobile phone technologies make frequent, brief adherence interviews possible in resource-limited settings; however, feasibility and acceptability are unknown. Interactive voice response (IVR) and short message service (SMS) text messaging were used to collect adherence data from 19 caregivers of HIV-infected children in Uganda. IVR calls or SMS quantifying missed doses were sent in the local language once weekly for 3–4 weeks. Qualitative interviews were conducted to assess participant impressions of the technologies. Participant interest and participation rates were high; however, weekly completion rates for adherence queries were low (0–33%), most commonly due to misunderstanding of personal identification numbers. Despite near ubiquity of mobile phone technology in resource-limited settings, individual level collection of healthcare data presents challenges. Further research is needed for effective training and incentive methods.
Literature
1.
go back to reference World Health Organization. Toward universal access: scaling up priority HIV/AIDS interventions in the health sector. Progress Report 2009, WHO Press: Geneva. World Health Organization. Toward universal access: scaling up priority HIV/AIDS interventions in the health sector. Progress Report 2009, WHO Press: Geneva.
2.
go back to reference Ickovics JR, Cameron A, Zackin R, et al. Consequences and determinants of adherence to antiretroviral medication: results from adult AIDS clinical trials group protocol 370. Antivir Ther. 2002;7(3):185–93.PubMed Ickovics JR, Cameron A, Zackin R, et al. Consequences and determinants of adherence to antiretroviral medication: results from adult AIDS clinical trials group protocol 370. Antivir Ther. 2002;7(3):185–93.PubMed
3.
go back to reference Lima VD, Harrigan R, Bangsberg DR, et al. The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. J Acquir Immune Defic Syndr. 2009;50(5):529–36.CrossRefPubMed Lima VD, Harrigan R, Bangsberg DR, et al. The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. J Acquir Immune Defic Syndr. 2009;50(5):529–36.CrossRefPubMed
4.
go back to reference Simoni JM, Kurth AE, Pearson CR, Pantalone DW, Merrill JO, Frick PA. Self-report measures of antiretroviral therapy adherence: a review with recommendations for HIV research and clinical management. AIDS Behav. 2006;10(3):227–45.CrossRefPubMed Simoni JM, Kurth AE, Pearson CR, Pantalone DW, Merrill JO, Frick PA. Self-report measures of antiretroviral therapy adherence: a review with recommendations for HIV research and clinical management. AIDS Behav. 2006;10(3):227–45.CrossRefPubMed
5.
go back to reference Nieuwkerk PT, Oort FJ. Self-reported adherence to antiretroviral therapy for HIV-1 infection and virologic treatment response: a meta-analysis. J Acquir Immune Defic Syndr. 2005;38(4):445–8.CrossRefPubMed Nieuwkerk PT, Oort FJ. Self-reported adherence to antiretroviral therapy for HIV-1 infection and virologic treatment response: a meta-analysis. J Acquir Immune Defic Syndr. 2005;38(4):445–8.CrossRefPubMed
6.
go back to reference Parienti JJ, Das-Douglas M, Massari V, et al. Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PLoS One. 2008;3(7):e2783.CrossRefPubMed Parienti JJ, Das-Douglas M, Massari V, et al. Not all missed doses are the same: sustained NNRTI treatment interruptions predict HIV rebound at low-to-moderate adherence levels. PLoS One. 2008;3(7):e2783.CrossRefPubMed
8.
go back to reference Beyond voice, in the economist. September 24, 2009. Beyond voice, in the economist. September 24, 2009.
9.
go back to reference Schroder KE, Johnson CJ. Interactive voice response technology to measure HIV-related behavior. Curr HIV/AIDS Rep. 2009;6(4):210–6.CrossRefPubMed Schroder KE, Johnson CJ. Interactive voice response technology to measure HIV-related behavior. Curr HIV/AIDS Rep. 2009;6(4):210–6.CrossRefPubMed
10.
go back to reference Schroder KE, Johnson CJ, Wiebe JS. Interactive voice response technology applied to sexual behavior self-reports: a comparison of three methods. AIDS Behav. 2007;11(2):313–23.CrossRefPubMed Schroder KE, Johnson CJ, Wiebe JS. Interactive voice response technology applied to sexual behavior self-reports: a comparison of three methods. AIDS Behav. 2007;11(2):313–23.CrossRefPubMed
11.
go back to reference Corkrey R, Parkinson L. Interactive voice response: review of studies 1989–2000. Behav Res Methods Instrum Comput. 2002;34(3):342–53.PubMed Corkrey R, Parkinson L. Interactive voice response: review of studies 1989–2000. Behav Res Methods Instrum Comput. 2002;34(3):342–53.PubMed
12.
go back to reference Perrine MW, Mundt JC, Searles JS, Lester LS. Validation of daily self-reported alcohol consumption using interactive voice response (IVR) technology. J Stud Alcohol. 1995;56(5):487–90.PubMed Perrine MW, Mundt JC, Searles JS, Lester LS. Validation of daily self-reported alcohol consumption using interactive voice response (IVR) technology. J Stud Alcohol. 1995;56(5):487–90.PubMed
13.
go back to reference Barta WD, Kiene SM, Tennen H, Abu-Hasaballah KS, Ferrer R. The idiographic study of inconsistent condom use behavior of persons living with HIV. AIDS Care. 2007;19(8):1058–64.CrossRefPubMed Barta WD, Kiene SM, Tennen H, Abu-Hasaballah KS, Ferrer R. The idiographic study of inconsistent condom use behavior of persons living with HIV. AIDS Care. 2007;19(8):1058–64.CrossRefPubMed
14.
go back to reference Fjeldsoe BS, Marshall AL, Miller YD. Behavior change interventions delivered by mobile telephone short-message service. Am J Prev Med. 2009;36(2):165–73.CrossRefPubMed Fjeldsoe BS, Marshall AL, Miller YD. Behavior change interventions delivered by mobile telephone short-message service. Am J Prev Med. 2009;36(2):165–73.CrossRefPubMed
17.
go back to reference Haberer J, Mellins C. Pediatric adherence to HIV antiretroviral therapy. Curr HIV/AIDS Rep. 2009;6(4):194–200.CrossRefPubMed Haberer J, Mellins C. Pediatric adherence to HIV antiretroviral therapy. Curr HIV/AIDS Rep. 2009;6(4):194–200.CrossRefPubMed
18.
go back to reference Ybarra ML, Bull SS. Current trends in internet- and cell phone-based HIV prevention and intervention programs. Curr HIV/AIDS Rep. 2007;4(4):201–7.CrossRefPubMed Ybarra ML, Bull SS. Current trends in internet- and cell phone-based HIV prevention and intervention programs. Curr HIV/AIDS Rep. 2007;4(4):201–7.CrossRefPubMed
19.
go back to reference Chang LW, Kagaayi J, Nakigozi G, et al. Responding to the human resource crisis: peer health workers, mobile phones, and HIV care in Rakai, Uganda. AIDS Patient Care STDS. 2008;22(3):173–4.CrossRefPubMed Chang LW, Kagaayi J, Nakigozi G, et al. Responding to the human resource crisis: peer health workers, mobile phones, and HIV care in Rakai, Uganda. AIDS Patient Care STDS. 2008;22(3):173–4.CrossRefPubMed
20.
go back to reference Curioso WH, Kurth AE. Access, use and perceptions regarding internet, cell phones and PDAs as a means for health promotion for people living with HIV in Peru. BMC Med Inform Decis Mak. 2007;7:24.CrossRefPubMed Curioso WH, Kurth AE. Access, use and perceptions regarding internet, cell phones and PDAs as a means for health promotion for people living with HIV in Peru. BMC Med Inform Decis Mak. 2007;7:24.CrossRefPubMed
21.
go back to reference Abayomi A, Goodridge W, Asika O. Wireless networks for surveillance, data capture and data management in the human immunodeficiency virus epidemic care and treatment programmes. Afr J Med Med Sci. 2006;35(Suppl):149–52.PubMed Abayomi A, Goodridge W, Asika O. Wireless networks for surveillance, data capture and data management in the human immunodeficiency virus epidemic care and treatment programmes. Afr J Med Med Sci. 2006;35(Suppl):149–52.PubMed
22.
go back to reference Puccio JA, Belzer M, Olson J, et al. The use of cell phone reminder calls for assisting HIV-infected adolescents and young adults to adhere to highly active antiretroviral therapy: a pilot study. AIDS Patient Care STDS. 2006;20(6):438–44.CrossRefPubMed Puccio JA, Belzer M, Olson J, et al. The use of cell phone reminder calls for assisting HIV-infected adolescents and young adults to adhere to highly active antiretroviral therapy: a pilot study. AIDS Patient Care STDS. 2006;20(6):438–44.CrossRefPubMed
26.
go back to reference Lester RT, Mills EJ, Kariri A, et al. The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol. Trials. 2009;10:87.CrossRefPubMed Lester RT, Mills EJ, Kariri A, et al. The HAART cell phone adherence trial (WelTel Kenya1): a randomized controlled trial protocol. Trials. 2009;10:87.CrossRefPubMed
27.
go back to reference Pope C, Ziebland S, Mays N. Qualitative research in health care. Analysing qualitative data. BMJ. 2000;320(7227):114–6.CrossRefPubMed Pope C, Ziebland S, Mays N. Qualitative research in health care. Analysing qualitative data. BMJ. 2000;320(7227):114–6.CrossRefPubMed
28.
go back to reference Ehiri JE, Anyanwu EC, Donath E, Kanu I, Jolly PE. AIDS-related stigma in sub-Saharan Africa: its contexts and potential intervention strategies. AIDS Public Policy J. 2005;20(1–2):25–39.PubMed Ehiri JE, Anyanwu EC, Donath E, Kanu I, Jolly PE. AIDS-related stigma in sub-Saharan Africa: its contexts and potential intervention strategies. AIDS Public Policy J. 2005;20(1–2):25–39.PubMed
29.
go back to reference Gaudine A, Glen L, Thuan TT, Dung do V. Perspectives of HIV-related stigma in a community in Vietnam: a qualitative study. Int J Nurs Stud. 2010;47(1):38–48.CrossRefPubMed Gaudine A, Glen L, Thuan TT, Dung do V. Perspectives of HIV-related stigma in a community in Vietnam: a qualitative study. Int J Nurs Stud. 2010;47(1):38–48.CrossRefPubMed
30.
go back to reference Intille SS. Ubiquitous computing technology for just-in-time motivation of behavior change. Stud Health Technol Inform. 2004;107(Pt 2):1434–7.PubMed Intille SS. Ubiquitous computing technology for just-in-time motivation of behavior change. Stud Health Technol Inform. 2004;107(Pt 2):1434–7.PubMed
31.
go back to reference Patrick K, Griswold WG, Raab F, Intille SS. Health and the mobile phone. Am J Prev Med. 2008;35(2):177–81.CrossRefPubMed Patrick K, Griswold WG, Raab F, Intille SS. Health and the mobile phone. Am J Prev Med. 2008;35(2):177–81.CrossRefPubMed
32.
go back to reference VanDevanter N, Parikh NS, Cohall RM, et al. Factors influencing participation in weekly support groups among women completing an HIV/STD intervention program. Women Health. 1999;30(1):15–34.PubMed VanDevanter N, Parikh NS, Cohall RM, et al. Factors influencing participation in weekly support groups among women completing an HIV/STD intervention program. Women Health. 1999;30(1):15–34.PubMed
33.
go back to reference Rigsby MO, Rosen MI, Beauvais JE, et al. Cue-dose training with monetary reinforcement: pilot study of an antiretroviral adherence intervention. J Gen Intern Med. 2000;15(12):841–7.CrossRefPubMed Rigsby MO, Rosen MI, Beauvais JE, et al. Cue-dose training with monetary reinforcement: pilot study of an antiretroviral adherence intervention. J Gen Intern Med. 2000;15(12):841–7.CrossRefPubMed
34.
go back to reference Nachega JB, Leisegang R, Bishai D, et al. Association of antiretroviral therapy adherence and health care costs. Ann Intern Med. 2010;152(1):18–25.PubMed Nachega JB, Leisegang R, Bishai D, et al. Association of antiretroviral therapy adherence and health care costs. Ann Intern Med. 2010;152(1):18–25.PubMed
35.
go back to reference Mills EJ, Nachega JB, Buchan I, et al. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA. 2006;296(6):679–90.CrossRefPubMed Mills EJ, Nachega JB, Buchan I, et al. Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis. JAMA. 2006;296(6):679–90.CrossRefPubMed
36.
go back to reference Vreeman RC, Wiehe SE, Pearce EC, Nyandiko WM. A systematic review of pediatric adherence to antiretroviral therapy in low- and middle-income countries. Pediatr Infect Dis J. 2008;27(8):686–91.CrossRefPubMed Vreeman RC, Wiehe SE, Pearce EC, Nyandiko WM. A systematic review of pediatric adherence to antiretroviral therapy in low- and middle-income countries. Pediatr Infect Dis J. 2008;27(8):686–91.CrossRefPubMed
37.
go back to reference Kaplan WA. Can the ubiquitous power of mobile phones be used to improve health outcomes in developing countries? Glob Health. 2006;2:9.CrossRef Kaplan WA. Can the ubiquitous power of mobile phones be used to improve health outcomes in developing countries? Glob Health. 2006;2:9.CrossRef
Metadata
Title
Challenges in Using Mobile Phones for Collection of Antiretroviral Therapy Adherence Data in a Resource-Limited Setting
Authors
Jessica E. Haberer
Julius Kiwanuka
Denis Nansera
Ira B. Wilson
David R. Bangsberg
Publication date
01-12-2010
Publisher
Springer US
Published in
AIDS and Behavior / Issue 6/2010
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-010-9720-1

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