Published in:
Open Access
01-02-2018 | Guideline
Guidelines for treatment of renal injury during cancer chemotherapy 2016
Authors:
Shigeo Horie, Mototsugu Oya, Masaomi Nangaku, Yoshinari Yasuda, Yasuhiro Komatsu, Motoko Yanagita, Yuko Kitagawa, Hiroyuki Kuwano, Hiroyuki Nishiyama, Chikashi Ishioka, Hiromasa Takaishi, Hideki Shimodaira, Akira Mogi, Yuichi Ando, Koji Matsumoto, Daisuke Kadowaki, Satoru Muto
Published in:
Clinical and Experimental Nephrology
|
Issue 1/2018
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Excerpt
Advances in cancer drug therapy have led to improvements in the outcomes of cancer patients, as well as increasing numbers of patients undergoing anticancer chemotherapy and molecularly targeted drug therapy. One adverse event associated with cancer drug therapy is nephrotoxicity, which impedes effective cancer therapy and diminishes the quality of life of cancer patients. Consequently, onco-nephrology has emerged as a new clinical field concerned with the management of nephrotoxicity in cancer drug therapy, creating expectations for advanced expertise and the accumulation of accurate evidence. However, while patients with renal impairment have heretofore undergone planning regarding administration of cancer drug therapy, procedures for nephropathy prevention, and measures for treatment of drug-induced nephrotoxicity in clinical settings based on tradition, experimental rules, and information from clinical trials, the soundness of the evidence for these practices has been uncertain. …