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Published in: Journal of Infection and Chemotherapy 3/2013

01-06-2013 | Guideline

Practice guidelines for therapeutic drug monitoring of vancomycin: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring

Authors: Kazuaki Matsumoto, Yoshio Takesue, Norio Ohmagari, Takahiro Mochizuki, Hiroshige Mikamo, Masafumi Seki, Shunji Takakura, Issei Tokimatsu, Yoshiko Takahashi, Kei Kasahara, Kenji Okada, Masahiro Igarashi, Masahiro Kobayashi, Yukihiro Hamada, Masao Kimura, Yoshifumi Nishi, Yusuke Tanigawara, Toshimi Kimura

Published in: Journal of Infection and Chemotherapy | Issue 3/2013

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Excerpt

Vancomycin (VCM) is a glycopeptide antibiotic that was introduced in Japan in November 1991. VCM is widely used for the treatment of invasive multi-resistant gram-positive bacterial infections, particularly those involving methicillin-resistant Staphylococcus aureus (MRSA) [15]. VCM use is associated with adverse events, including "red man syndrome" [6], nephrotoxicity [79], and ototoxicity [10, 11]. Compared with other antimicrobial agents, the therapeutic range is narrow in VCM, and therapeutic drug monitoring (TDM) is required for maximizing efficacy while minimizing the onset of these toxicities [1214]. …
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Metadata
Title
Practice guidelines for therapeutic drug monitoring of vancomycin: a consensus review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring
Authors
Kazuaki Matsumoto
Yoshio Takesue
Norio Ohmagari
Takahiro Mochizuki
Hiroshige Mikamo
Masafumi Seki
Shunji Takakura
Issei Tokimatsu
Yoshiko Takahashi
Kei Kasahara
Kenji Okada
Masahiro Igarashi
Masahiro Kobayashi
Yukihiro Hamada
Masao Kimura
Yoshifumi Nishi
Yusuke Tanigawara
Toshimi Kimura
Publication date
01-06-2013
Publisher
Springer Japan
Published in
Journal of Infection and Chemotherapy / Issue 3/2013
Print ISSN: 1341-321X
Electronic ISSN: 1437-7780
DOI
https://doi.org/10.1007/s10156-013-0599-4

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