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Published in: Lasers in Medical Science 8/2018

01-11-2018 | Original Article

Foaming of blood in endovenous laser treatment

Authors: Vladimir Chudnovskii, Aleksandr Mayor, Artem Kiselev, Vladimir Yusupov

Published in: Lasers in Medical Science | Issue 8/2018

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Abstract

This work is dedicated to a challenging issue of modern phlebology—establishment of a physical mechanism of the endovenous laser treatment (EVLT) against great saphenous vein incompetence (protuberant varicosities). Using optical and acoustical methods, we have studied the laser-induced formation of microbubbles in an aqueous solution of surface-active substances, serum, and blood directly in patients while conducting EVLT of the great saphenous vein in a clinical setting. We have used lasers with wavelengths 0.97 and 1.47 μm. Their radiation was transmitted through a quartz-quartz polymer fiber 600 μm in diameter. It has been found that in all cases, the laser beam with moderate power (1–10 W) supplied through an optical fiber leads to the formation of micro-bubbled foam. It has been shown that laser exposure during EVLT induces blood boiling, which results in heating of the venous walls (thermal destruction of the intima) and provides effective foam occlusion of the blood vessels (hemostasis). Necessary and sufficient conditions for a successful EVLT are associated with the thermal destruction of intima and laser-induced foam hemostasis.
Literature
1.
go back to reference Rabe E, Berboth G, Pannier F (2016) Epidemiology of chronic venous diseases. Wien Med Wochenschr 166:260–263CrossRef Rabe E, Berboth G, Pannier F (2016) Epidemiology of chronic venous diseases. Wien Med Wochenschr 166:260–263CrossRef
2.
go back to reference Min RJ, Khilnani N, Zimmet SE (2003) Endovenous laser treatment of saphenous vein reflux: long-term results. J Vasc Interv Radiol 14:991–996CrossRef Min RJ, Khilnani N, Zimmet SE (2003) Endovenous laser treatment of saphenous vein reflux: long-term results. J Vasc Interv Radiol 14:991–996CrossRef
3.
go back to reference Min RJ, Zimmet SE, Isaacs MN, Forrestal MD (2001) Endovenous laser treatment of the incompetent greater saphenous vein. J Vasc Interv Radiol 12:1167–1171CrossRef Min RJ, Zimmet SE, Isaacs MN, Forrestal MD (2001) Endovenous laser treatment of the incompetent greater saphenous vein. J Vasc Interv Radiol 12:1167–1171CrossRef
4.
go back to reference Parente EJ, Rosenblatt M (2003) Endovenous laser treatment to promote venous occlusion. Lasers Surg Med 33:115–118CrossRef Parente EJ, Rosenblatt M (2003) Endovenous laser treatment to promote venous occlusion. Lasers Surg Med 33:115–118CrossRef
5.
go back to reference Chang CJ, Chua JJ (2002) Endovenous laser photocoagulation (EVLP) for varicose veins. Lasers Surg Med 31:257–262CrossRef Chang CJ, Chua JJ (2002) Endovenous laser photocoagulation (EVLP) for varicose veins. Lasers Surg Med 31:257–262CrossRef
10.
go back to reference Weiss RA, Weiss MA, Eimpunth S, Wheeler S, Udompunturak S, Beasley KL (2015) Comparative outcomes of different endovenous thermal ablation systems on great and small saphenous vein insufficiency: long-term results. Lasers Surg Med 47:156–160CrossRef Weiss RA, Weiss MA, Eimpunth S, Wheeler S, Udompunturak S, Beasley KL (2015) Comparative outcomes of different endovenous thermal ablation systems on great and small saphenous vein insufficiency: long-term results. Lasers Surg Med 47:156–160CrossRef
11.
go back to reference Mordon SR, Wassmer B, Zemmouri J (2007) Mathematical modeling of 980-nm and 1320-nm endovenous laser treatment. Lasers Surg Med 39:256–265CrossRef Mordon SR, Wassmer B, Zemmouri J (2007) Mathematical modeling of 980-nm and 1320-nm endovenous laser treatment. Lasers Surg Med 39:256–265CrossRef
15.
go back to reference van den Bos RR, Kockaert MA, Neumann HM, Bremmer RH, Nijsten T, van Gemert MJ (2009) Heat conduction from the exceedingly hot fiber tip contributes to the endovenous laser ablation of varicose veins. Lasers Med Sci 24(2):247–251CrossRef van den Bos RR, Kockaert MA, Neumann HM, Bremmer RH, Nijsten T, van Gemert MJ (2009) Heat conduction from the exceedingly hot fiber tip contributes to the endovenous laser ablation of varicose veins. Lasers Med Sci 24(2):247–251CrossRef
16.
go back to reference Stokbroekx T, de Boer A, Verdaasdonk RM, Vuylsteke ME, Mordon SR (2014) Commonly used fiber tips in endovenous laser ablation (EVLA): an analysis of technical differences. Lasers Med Sci 29(2):501–507CrossRef Stokbroekx T, de Boer A, Verdaasdonk RM, Vuylsteke ME, Mordon SR (2014) Commonly used fiber tips in endovenous laser ablation (EVLA): an analysis of technical differences. Lasers Med Sci 29(2):501–507CrossRef
17.
go back to reference Amzayyb M, van den Bos RR, Kodach VM, de Bruin DM, Nijsten T, Neumann HAM, van Gemert MJC (2010) Carbonized blood deposited on fibres during 810, 940 and 1,470 nm endovenous laser ablation: thickness and absorption by optical coherence tomography. Lasers Med Sci 25:439–447CrossRef Amzayyb M, van den Bos RR, Kodach VM, de Bruin DM, Nijsten T, Neumann HAM, van Gemert MJC (2010) Carbonized blood deposited on fibres during 810, 940 and 1,470 nm endovenous laser ablation: thickness and absorption by optical coherence tomography. Lasers Med Sci 25:439–447CrossRef
18.
go back to reference Chudnovskii VM, Yusupov VI, Dydykin AV, Nevozhai VI, Kisilev AY, Zhukov SA, Bagratashvili VN (2017) Laser-induced boiling of biological liquids in medical technologies. Quantum Electronics 47:361–370CrossRef Chudnovskii VM, Yusupov VI, Dydykin AV, Nevozhai VI, Kisilev AY, Zhukov SA, Bagratashvili VN (2017) Laser-induced boiling of biological liquids in medical technologies. Quantum Electronics 47:361–370CrossRef
19.
go back to reference Ignatieva NY, Zakharkina OL, Masayshvili CV, Maximov SV, Bagratashvili VN, Lunin VV (2017) The role of laser power and pullback velocity in the endovenous laser ablation efficacy: an experimental study. Lasers Med Sci 32:1105–1110CrossRef Ignatieva NY, Zakharkina OL, Masayshvili CV, Maximov SV, Bagratashvili VN, Lunin VV (2017) The role of laser power and pullback velocity in the endovenous laser ablation efficacy: an experimental study. Lasers Med Sci 32:1105–1110CrossRef
20.
go back to reference Farn RJ (2006) Chemistry and technology of surfactants. Blackwell Publishing, OxfordCrossRef Farn RJ (2006) Chemistry and technology of surfactants. Blackwell Publishing, OxfordCrossRef
21.
go back to reference Cavezzi A, Frullini A, Ricci S, Tessari L (2002) Treatment of varicose veins by foam sclerotherapy: two clinical series. Phlebology 17(1):13–18CrossRef Cavezzi A, Frullini A, Ricci S, Tessari L (2002) Treatment of varicose veins by foam sclerotherapy: two clinical series. Phlebology 17(1):13–18CrossRef
22.
go back to reference Curcio JA, Petty CC (1951) The near infrared absorption spectrum of liquid water. JOSA 41(5):302–304CrossRef Curcio JA, Petty CC (1951) The near infrared absorption spectrum of liquid water. JOSA 41(5):302–304CrossRef
24.
go back to reference Yusupov VI, Tsypina SI, Bagratashvili VN (2014) Trapping of nanoparticles in a liquid by laser-induced microbubbles. Laser Phys Lett 11:116001CrossRef Yusupov VI, Tsypina SI, Bagratashvili VN (2014) Trapping of nanoparticles in a liquid by laser-induced microbubbles. Laser Phys Lett 11:116001CrossRef
25.
go back to reference Schaberle W (2011) Ultrasonography in vascular diagnosis: a therapy oriented textbook and atlas, 2nd edn. Springer-Verlag, BerlinCrossRef Schaberle W (2011) Ultrasonography in vascular diagnosis: a therapy oriented textbook and atlas, 2nd edn. Springer-Verlag, BerlinCrossRef
26.
go back to reference Jia X, Mowatt G, Burr JM, Cassar K, Cook J, Fraser C (2007) Systematic review of foam sclerotherapy for varicose veins. Br J Surg 94:925–936CrossRef Jia X, Mowatt G, Burr JM, Cassar K, Cook J, Fraser C (2007) Systematic review of foam sclerotherapy for varicose veins. Br J Surg 94:925–936CrossRef
27.
go back to reference Hamann SAS, Giang J, De Maeseneer MGR, Nijsten TEC, van den Bos RR (2018) Five year results of great saphenous vein treatment: a meta-analysis. J Vasc Surg 67:359CrossRef Hamann SAS, Giang J, De Maeseneer MGR, Nijsten TEC, van den Bos RR (2018) Five year results of great saphenous vein treatment: a meta-analysis. J Vasc Surg 67:359CrossRef
Metadata
Title
Foaming of blood in endovenous laser treatment
Authors
Vladimir Chudnovskii
Aleksandr Mayor
Artem Kiselev
Vladimir Yusupov
Publication date
01-11-2018
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 8/2018
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-018-2552-3

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