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European Journal of Clinical Microbiology & Infectious Diseases

Published in:

18-07-2022 | Antibiotic | Brief Report

Clinical and microbiological characteristics of reflux cholangitis following bilio-enteric anastomosis

Authors: Audrey Le Bot, Aurélien Sokal, Anaïs Choquet, Frédérique Maire, Bruno Fantin, Alain Sauvanet, Victoire de Lastours

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 8/2022

Abstract

Twenty-five patients with reflux cholangitis (RC) defined as acute cholangitis (AC) with normal abdominal imaging occurring > 3 months after bilioenteric anastomosis were described and compared to 116 AC patients with biliary obstruction (tumoral, lithiasis). RC episodes occurred a median 4.5 months after surgery; 18 (72%) had recurrent RC (n ≥ 3). RC episodes were less severe than obstructive AC; the outcome was favorable with short antibiotic courses and no selection of antibiotic-resistance. However, multiple recurrent RC occurred in 20 patients (80%). Prophylactic or pre-emptive antibiotics were successful in 3 and 11 patients. Revision surgery for jejunal loop lengthening was successful in 2/4 patients.

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Title: Clinical and microbiological characteristics of reflux cholangitis following bilio-enteric anastomosis
Authors: Audrey Le Bot
Aurélien Sokal
Anaïs Choquet
Frédérique Maire
Bruno Fantin
Alain Sauvanet
Victoire de Lastours
Publication date: 18-07-2022
Publisher: Springer Berlin Heidelberg
Keywords: Antibiotic
Cholangitis
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 8/2022
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-022-04468-7

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