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European Journal of Clinical Microbiology & Infectious Diseases

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01-01-2022 | Brief Report

Population-based surveillance of Enterobacter cloacae complex causing blood stream infections in a centralized Canadian region

Authors: William Stokes, Gisele Peirano, Yasufumi Matsumara, Diego Nobrega, Johann D. D. Pitout

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 1/2022

Abstract

Active population-based surveillance determined clinical factors, susceptibility patterns, incidence rates (IR), and genomics among Enterobacter cloacae complex (n = 154) causing blood stream infections in a centralized Canadian region (2015–2017). The annual population IR was 1.2/100,000 (95% CI 0.9–16) in 2015, 1.4/100,000 (95% CI 1.1–1.9) in 2016, and 1.5/100,000 (95% CI 1.2–2.0) in 2017, affecting mainly elderly males with underlying comorbid conditions in the hospital setting. E. cloacae complex was dominated by polyclonal subspecies (i.e., E. hormaechei subsp. steigerwaltii, subsp. hoffmanni and subsp. xiangfangesis). Antimicrobial resistant determinants were rare. This study provided novel information about Enterobacter genomics in a well-defined human population.

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Title: Population-based surveillance of Enterobacter cloacae complex causing blood stream infections in a centralized Canadian region
Authors: William Stokes
Gisele Peirano
Yasufumi Matsumara
Diego Nobrega
Johann D. D. Pitout
Publication date: 01-01-2022
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 1/2022
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-021-04309-z

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