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01-03-2022 | Cerebral Sinus Venous Thrombosis | COVID-19

Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach

Authors: Laura Mirandola, Giulia Arena, Maria Pagliaro, Andrea Boghi, Andrea Naldi, Davide Castellano, Antonella Vaccarino, Daniela Silengo, Franco Aprà, Roberto Cavallo, Sergio Livigni

Published in: Neurological Sciences | Issue 3/2022

Abstract

We report a case of massive cerebral venous sinus thrombosis in the contest of vaccine-induced immune thrombotic thrombocytopenia that required the rapid coordination of many specialists from different departments, notably emergency, neurology, neuroradiology, hematology, and neurosurgery. The patient was rapidly treated with steroids, immunoglobulin, and fondaparinux. She underwent within 6 h after hospital admission a mechanical thrombectomy in order to allow flow restoration in cerebral venous systems. Neuroendovascular treatment in cerebral venous thrombosis related to VITT has never been described before. It can represent a complementary tool along with the other therapies and a multidisciplinary approach.

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Title: Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach
Authors: Laura Mirandola
Giulia Arena
Maria Pagliaro
Andrea Boghi
Andrea Naldi
Davide Castellano
Antonella Vaccarino
Daniela Silengo
Franco Aprà
Roberto Cavallo
Sergio Livigni
Publication date: 01-03-2022
Publisher: Springer International Publishing
Keywords: Cerebral Sinus Venous Thrombosis
Venous Thrombosis
Edema
Thrombocytopenia
CT Angiography
Thrombosis
Venous Thrombosis
Thrombectomy
Fondaparinux
Published in: Neurological Sciences / Issue 3/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05805-y

At a glance: The STEP trials

Springer Medicine

Massive cerebral venous sinus thrombosis in vaccine-induced immune thrombotic thrombocytopenia after ChAdOx1 nCoV-19 serum: case report of a successful multidisciplinary approach

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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