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01-10-2021 | Nerve Injury | Review Article

Efficacy of low-level laser therapy in nerve injury repair—a new era in therapeutic agents and regenerative treatments

Authors: Xellen Cunha Muniz, Ana Carolina Correa de Assis, Bruna Stefane Alves de Oliveira, Luiz Fernando Romanholo Ferreira, Muhammad Bilal, Hafiz M. N. Iqbal, Renato Nery Soriano

Published in: Neurological Sciences | Issue 10/2021

Abstract

Background

Traumatic nerve injuries may result in severe motor dysfunctions. Although the microenvironment of peripheral axons favors their regeneration, regenerative process is not always successful.

Purpose

We reviewed and discussed the main findings obtained with low-level laser therapy (LLLT), a therapeutic intervention that has been employed in order to achieve an optimized regeneration process in peripheral axons.

Scope

Disseminating the best available evidence for the effectiveness of this therapeutic strategy can potentially improve the statistics of success in the clinical treatment of nerve injuries. We found evidence that LLLT optimizes the regeneration of peripheral axons, improving motor function, especially in animal models. Nonetheless, further clinical evidence is still needed before LLLT can be strongly recommended. Although the results are promising, the elucidation of the mechanisms of action and safety assessment are necessary to support highquality clinical studies.

Conclusion

The present careful compilation of findings with consistent pro-regenerative evidence and published in respected scientific journals can be valuable for health professionals and researchers in the field, possibly contributing to achieve more promising results in future randomized controlled trials and interventions, providing better prognosis for clinical practice.

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Title: Efficacy of low-level laser therapy in nerve injury repair—a new era in therapeutic agents and regenerative treatments
Authors: Xellen Cunha Muniz
Ana Carolina Correa de Assis
Bruna Stefane Alves de Oliveira
Luiz Fernando Romanholo Ferreira
Muhammad Bilal
Hafiz M. N. Iqbal
Renato Nery Soriano
Publication date: 01-10-2021
Publisher: Springer International Publishing
Keywords: Nerve Injury
Laser
Published in: Neurological Sciences / Issue 10/2021
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05478-7

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Efficacy of low-level laser therapy in nerve injury repair—a new era in therapeutic agents and regenerative treatments

Abstract

Background

Purpose

Scope

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Background

Purpose

Scope

Conclusion

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