Published in:
01-08-2021 | Magnetic Resonance Imaging | Original Article
Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response
Authors:
Rui Li, Cong Li, Zhifeng Mao, Qiao Huang, Yaqing Shu, Yanyu Chang, Jingqi Wang, Yuge Wang, Wei Qiu
Published in:
Neurological Sciences
|
Issue 8/2021
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Abstract
Background
Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date.
Objective
To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.
Methods
We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.
Results
We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.
Conclusion
Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.