Skip to main content
Top
Published in: Neurological Sciences 12/2019

01-12-2019 | Hypotension | Review Article

Optic nerve sheath diameter: present and future perspectives for neurologists and critical care physicians

Authors: Piergiorgio Lochner, Marek Czosnyka, Andrea Naldi, Epameinondas Lyros, Paolo Pelosi, Shrey Mathur, Klaus Fassbender, Chiara Robba

Published in: Neurological Sciences | Issue 12/2019

Login to get access

Abstract

Background

Estimation of intracranial pressure (ICP) may be helpful in the management of neurological critically ill patients. It has been shown that ultrasonography of the optic nerve sheath diameter (ONSD) is a reliable tool for non-invasive estimation of increased intracranial pressure (ICP) at hospital admission or in intensive care. Less is known about the estimation of increased ICP and usefulness of ONSD in the prehospital setting. The aim of this review was to elucidate both prevailing and novel applications of ONSD for neurologists and critical care physicians.

Methods

In this review, we discuss the technique and the novel approach of ONSD measurement, the clinical applications of ONSD in neurology and critical care patients.

Results

ONSD measurement is simple, easy to learn, and has diverse applications. ONSD has utility for ICP measurement in intracranial hemorrhage and ischemic stroke, meningitis and encephalitis, and idiopathic intracranial hypertension (IIH). It is also valuable for lesser known syndromes, where an increase of ICP is postulated, such as acute mountain sickness and posterior reversible encephalopathy syndrome. ONSD changes develop in inflammatory or ischemic optic neuropathies. Some papers demonstrate the usefulness of ONSD studies in symptomatic intracranial hypotension.

Conclusions

ONSD is a safe and low-cost bedside tool with the potential of screening patients who need other neuroimaging and those who may need an invasive measurement of ICP.
Literature
10.
go back to reference Helmke K, Hansen HC (1996) Fundamentals of transorbital sonographic evaluation of optic nerve sheath expansion under intracranial hypertension II. Patient study. Pediatr Radiol 26:706–710CrossRef Helmke K, Hansen HC (1996) Fundamentals of transorbital sonographic evaluation of optic nerve sheath expansion under intracranial hypertension II. Patient study. Pediatr Radiol 26:706–710CrossRef
13.
go back to reference Fowlkes JB, Holland CK (2000) Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine. J Ultrasound Med 19:69–72CrossRef Fowlkes JB, Holland CK (2000) Mechanical bioeffects from diagnostic ultrasound: AIUM consensus statements. American Institute of Ultrasound in Medicine. J Ultrasound Med 19:69–72CrossRef
14.
go back to reference Ballantyne SA, O'Neill G, Hamilton R, Hollman AS (2002) Observer variation in the sonographic measurement of optic nerve sheath diameter in normal adults. Eur J Ultrasound 15:145–149CrossRef Ballantyne SA, O'Neill G, Hamilton R, Hollman AS (2002) Observer variation in the sonographic measurement of optic nerve sheath diameter in normal adults. Eur J Ultrasound 15:145–149CrossRef
19.
go back to reference Helmke K, Hansen HC (1996) Fundamentals of transorbital sonographic evaluation of optic nerve sheath expansion under intracranial hypertension. I. Experimental study. Pediatr Radiol 26:701–705CrossRef Helmke K, Hansen HC (1996) Fundamentals of transorbital sonographic evaluation of optic nerve sheath expansion under intracranial hypertension. I. Experimental study. Pediatr Radiol 26:701–705CrossRef
25.
go back to reference Ertl M, Aigner R, Krost M, Karnasova Z, Muller K, Naumann M, Schlachetzki F (2017) Measuring changes in the optic nerve sheath diameter in patients with idiopathic normal-pressure hydrocephalus: a useful diagnostic supplement to spinal tap tests. Eur J Neurol 24:461–467. https://doi.org/10.1111/ene.13225 CrossRefPubMed Ertl M, Aigner R, Krost M, Karnasova Z, Muller K, Naumann M, Schlachetzki F (2017) Measuring changes in the optic nerve sheath diameter in patients with idiopathic normal-pressure hydrocephalus: a useful diagnostic supplement to spinal tap tests. Eur J Neurol 24:461–467. https://​doi.​org/​10.​1111/​ene.​13225 CrossRefPubMed
49.
go back to reference Ross RT (1985) The random nature of cerebral mountain sickness. Lancet 1:990–991CrossRef Ross RT (1985) The random nature of cerebral mountain sickness. Lancet 1:990–991CrossRef
57.
go back to reference Newman WD, Hollman AS, Dutton GN, Carachi R (2002) Measurement of optic nerve sheath diameter by ultrasound: a means of detecting acute raised intracranial pressure in hydrocephalus. Br J Ophthalmol 86:1109–1113CrossRef Newman WD, Hollman AS, Dutton GN, Carachi R (2002) Measurement of optic nerve sheath diameter by ultrasound: a means of detecting acute raised intracranial pressure in hydrocephalus. Br J Ophthalmol 86:1109–1113CrossRef
58.
go back to reference Foroozan R, Buono LM, Savino PJ, Sergott RC (2002) Acute demyelinating optic neuritis. Curr Opin Ophthalmol 13:375–380CrossRef Foroozan R, Buono LM, Savino PJ, Sergott RC (2002) Acute demyelinating optic neuritis. Curr Opin Ophthalmol 13:375–380CrossRef
59.
go back to reference Youl BD et al (1991) The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. Brain 114(Pt 6):2437–2450CrossRef Youl BD et al (1991) The pathophysiology of acute optic neuritis. An association of gadolinium leakage with clinical and electrophysiological deficits. Brain 114(Pt 6):2437–2450CrossRef
61.
go back to reference Elvin A, Andersson T, Soderstrom M (1998) Optic neuritis. Doppler ultrasonography compared with MR and correlated with visual evoked potential assessments. Acta Radiol 39:243–248PubMed Elvin A, Andersson T, Soderstrom M (1998) Optic neuritis. Doppler ultrasonography compared with MR and correlated with visual evoked potential assessments. Acta Radiol 39:243–248PubMed
62.
go back to reference Gerling J, Janknecht P, Hansen LL, Kommerell G (1997) Diameter of the optic nerve in idiopathic optic neuritis and in anterior ischemic optic neuropathy. Int Ophthalmol 21:131–135CrossRef Gerling J, Janknecht P, Hansen LL, Kommerell G (1997) Diameter of the optic nerve in idiopathic optic neuritis and in anterior ischemic optic neuropathy. Int Ophthalmol 21:131–135CrossRef
65.
go back to reference Neroev VV, Karlova IZ, Zaitseva OV, Kruzhkova GV, Boiko AN (2001) Role of ultrasonic B-scanning in differential diagnosis and prognosis of the course of optic neuritis. Vestn oftalmol 117:25–29PubMed Neroev VV, Karlova IZ, Zaitseva OV, Kruzhkova GV, Boiko AN (2001) Role of ultrasonic B-scanning in differential diagnosis and prognosis of the course of optic neuritis. Vestn oftalmol 117:25–29PubMed
66.
go back to reference Stefanovic IB, Jovanovic M, Krnjaja BD, Veselinovic D, Jovanovic P (2010) Influence of retrobulbar neuritis and papillitis on echographically measured optic nerve diameter. Vojnosanit Pregl 67:32–35CrossRef Stefanovic IB, Jovanovic M, Krnjaja BD, Veselinovic D, Jovanovic P (2010) Influence of retrobulbar neuritis and papillitis on echographically measured optic nerve diameter. Vojnosanit Pregl 67:32–35CrossRef
70.
go back to reference Bernal W, Wendon J (1999) Acute liver failure; clinical features and management. Eur J Gastroenterol Hepatol 11:977–984CrossRef Bernal W, Wendon J (1999) Acute liver failure; clinical features and management. Eur J Gastroenterol Hepatol 11:977–984CrossRef
71.
go back to reference Ware AJ, D’Agostino AN, Combes B (1971) Cerebral edema: a major complication of massive hepatic necrosis. Gastroenterology 61:877–884CrossRef Ware AJ, D’Agostino AN, Combes B (1971) Cerebral edema: a major complication of massive hepatic necrosis. Gastroenterology 61:877–884CrossRef
73.
go back to reference Peck M, Wendon J, Sizer E, Auzinger G, Bernal W (2010) Intracranial pressure monitoring in acute liver failure: a review of 10 years experience. Crit Care 14:P542CrossRef Peck M, Wendon J, Sizer E, Auzinger G, Bernal W (2010) Intracranial pressure monitoring in acute liver failure: a review of 10 years experience. Crit Care 14:P542CrossRef
76.
go back to reference Ganschow R, Nolkemper D, Helmke K, Harps E, Commentz JC, Broering DC, Pothmann W, Rogiers X, Hellwege HH, Burdelski M (2000) Intensive care management after pediatric liver transplantation: a single-center experience. Pediatr Transplant 4:273–279CrossRef Ganschow R, Nolkemper D, Helmke K, Harps E, Commentz JC, Broering DC, Pothmann W, Rogiers X, Hellwege HH, Burdelski M (2000) Intensive care management after pediatric liver transplantation: a single-center experience. Pediatr Transplant 4:273–279CrossRef
82.
go back to reference Citerio G, Vascotto E, Villa F, Celotti S, Pesenti A (2001) Induced abdominal compartment syndrome increases intracranial pressure in neurotrauma patients: a prospective study. Crit Care Med 29:1466–1471CrossRef Citerio G, Vascotto E, Villa F, Celotti S, Pesenti A (2001) Induced abdominal compartment syndrome increases intracranial pressure in neurotrauma patients: a prospective study. Crit Care Med 29:1466–1471CrossRef
83.
go back to reference Cooke SJ, Paterson-Brown S (2001) Association between laparoscopic abdominal surgery and postoperative symptoms of raised intracranial pressure. Surg Endosc 15:723–725CrossRef Cooke SJ, Paterson-Brown S (2001) Association between laparoscopic abdominal surgery and postoperative symptoms of raised intracranial pressure. Surg Endosc 15:723–725CrossRef
88.
go back to reference Ertl M, Schierling W, Kasprzak P, Schomig B, Bruckl C, Schlachetzki F, Pfister K (2015) Optic nerve sheath diameter measurement to identify high-risk patients for spinal ischemia after endovascular thoracoabdominal aortic aneurysm repair. J Neuroimaging 25:910–915. https://doi.org/10.1111/jon.12234 CrossRefPubMed Ertl M, Schierling W, Kasprzak P, Schomig B, Bruckl C, Schlachetzki F, Pfister K (2015) Optic nerve sheath diameter measurement to identify high-risk patients for spinal ischemia after endovascular thoracoabdominal aortic aneurysm repair. J Neuroimaging 25:910–915. https://​doi.​org/​10.​1111/​jon.​12234 CrossRefPubMed
92.
go back to reference Gerber S et al (2017) Automatic estimation of the optic nerve sheath diameter from ultrasound images imaging for patient-customized simulations and systems for point-of-care ultrasound : International Workshops, BIVPCS 2017 and POCUS 2017, held in conjunction with MICCAI 2017, Quebec City, QC 10549:113–120 https://doi.org/10.1007/978-3-319-67552-7_14 CrossRef Gerber S et al (2017) Automatic estimation of the optic nerve sheath diameter from ultrasound images imaging for patient-customized simulations and systems for point-of-care ultrasound : International Workshops, BIVPCS 2017 and POCUS 2017, held in conjunction with MICCAI 2017, Quebec City, QC 10549:113–120 https://​doi.​org/​10.​1007/​978-3-319-67552-7_​14 CrossRef
Metadata
Title
Optic nerve sheath diameter: present and future perspectives for neurologists and critical care physicians
Authors
Piergiorgio Lochner
Marek Czosnyka
Andrea Naldi
Epameinondas Lyros
Paolo Pelosi
Shrey Mathur
Klaus Fassbender
Chiara Robba
Publication date
01-12-2019
Publisher
Springer International Publishing
Published in
Neurological Sciences / Issue 12/2019
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI
https://doi.org/10.1007/s10072-019-04015-x

Other articles of this Issue 12/2019

Neurological Sciences 12/2019 Go to the issue