Published in:
01-05-2022 | Vasculitis | Clinical Image
Emergence of de novo cutaneous vasculitis post coronavirus disease (COVID-19) vaccination
Published in: Clinical Rheumatology | Issue 5/2022
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A 62-year-old Asian female presented to the Emergency Department with a bilateral lower limb non-blanching petechial rash 7 days after the first dose of the ChAdOx1 nCoV-19 vaccine (Astra-Zeneca) COVID-19 vaccination (Fig. 1A). Her symptoms were associated with a generalised headache, myalgia, and symmetrical large joint arthralgias. She was afebrile, had no appreciable synovitis, and the rest of the physical examination was unremarkable.
Fig. 1
Leukocytoclastic vasculitis following coronavirus (COVID-19) vaccination. Non-blanching bilateral lower limb vasculitic rash (A). On microscopy, perivascular inflammation was noted (arrow) (B) with deposition of C3 complement (C) and fibrinogen (D) in the superficial dermal vessels. Micrographs are taken at 100 × magnification
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