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01-11-2020 | Osteoarthrosis | Editorial

Mitochondrial DNA in osteoarthritis disease

Authors: Francisco J. Blanco, Ignacio Rego-Pérez

Published in: Clinical Rheumatology | Issue 11/2020

Excerpt

Osteoarthritis (OA) is the most prevalent chronic joint disease, and we actually know that the activation of maladaptive responses to injury, including pro-inflammatory pathways, leads to the loss of normal joint function characterized by cartilage degradation, bone remodeling, osteophyte formation, and joint inflammation [1]. Recent insights into the epidemiology and impact of OA on patients have clearly established that OA is a severe disease of the whole joint as an organ, with large unmet medical needs. …

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Title: Mitochondrial DNA in osteoarthritis disease
Authors: Francisco J. Blanco
Ignacio Rego-Pérez
Publication date: 01-11-2020
Publisher: Springer International Publishing
Keywords: Osteoarthrosis
Osteoarthrosis
Published in: Clinical Rheumatology / Issue 11/2020
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI: https://doi.org/10.1007/s10067-020-05406-8

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