Skip to main content
Top
Published in: Hernia 4/2011

01-08-2011 | Original Article

Elastic fibers in the anterior abdominal wall

Authors: A. Fachinelli, M. R. M. Trindade, F. A. Fachinelli

Published in: Hernia | Issue 4/2011

Login to get access

Abstract

Purpose

The aim of this study was to substantiate the hypothesis as to whether an altered amount of elastic fibers in the linea alba aponeurosis occurs or not in anterior abdominal wall hernias (epigastric, incisional and umbilical), comparing the findings with those of a control group of cadavers without hernias.

Methods

Thirty patients (15 males and 15 females) with anterior abdominal wall hernias were evaluated for analysis of the elastin content in samples from the linea alba aponeurosis, with immunohistochemistry and orcein staining using videomorphometry.

Results

The results showed a greater amount of elastin in patients with abdominal wall hernias compared to the control group of cadavers without hernias (P < 0.05). The elastic fibers were greatly thickened, tortuous and fragmented in the patients.

Conclusion

It is essential to analyze the anterior abdominal wall concerning its anatomical condition and histological components. Altered collagen and elastic fibers play an important role in hernia formation, indicating that the main factor may be biological.
Literature
1.
go back to reference Corsale I, Palladino E (2000) Diagnosi e terapia delle ernie epigastriche. Min Chir 55(9):607–610 Corsale I, Palladino E (2000) Diagnosi e terapia delle ernie epigastriche. Min Chir 55(9):607–610
2.
go back to reference Zheng H, Si Z, Kasperk R, Bhardway R, Schumpelick V, Klinge U, Klosterhalfen B (2002) Recurrent inguinal hernia: disease of the collagen matrix? World J Surg 26:401–408PubMedCrossRef Zheng H, Si Z, Kasperk R, Bhardway R, Schumpelick V, Klinge U, Klosterhalfen B (2002) Recurrent inguinal hernia: disease of the collagen matrix? World J Surg 26:401–408PubMedCrossRef
3.
go back to reference Ozdogan M, Yildiz F, Gurer A, Orhun S, Kulacoglu H, Aydin R (2006) Changes in collagen and elastic fiber contents of the skin, rectus sheath, transversalis fascia and peritoneum in primary inguinal hernia patients. Bratisl Lek Listy 107(6–7):235–238PubMed Ozdogan M, Yildiz F, Gurer A, Orhun S, Kulacoglu H, Aydin R (2006) Changes in collagen and elastic fiber contents of the skin, rectus sheath, transversalis fascia and peritoneum in primary inguinal hernia patients. Bratisl Lek Listy 107(6–7):235–238PubMed
4.
go back to reference Read RC (2004) Inguinal herniation in the adult, defect or disease: a surgeon’s odyssey. Hernia 8:296–299PubMedCrossRef Read RC (2004) Inguinal herniation in the adult, defect or disease: a surgeon’s odyssey. Hernia 8:296–299PubMedCrossRef
5.
go back to reference Pans A, Albert A, Lapire CM, Nusgens B (2001) Biochemical study of collagen in adult groin hernias. J Surg Res 95:107–113PubMedCrossRef Pans A, Albert A, Lapire CM, Nusgens B (2001) Biochemical study of collagen in adult groin hernias. J Surg Res 95:107–113PubMedCrossRef
6.
go back to reference Rosch R, Klinge U, Si Z, Junge K, Klosterhalfen B, Schumpelick V (2002) A role for the collagen I/III and MMP-I/-13 genes in primary inguinal hernia. BMC Med Genet 3:2 (www.biomedcentral.com/1471- 2350/3/2) Rosch R, Klinge U, Si Z, Junge K, Klosterhalfen B, Schumpelick V (2002) A role for the collagen I/III and MMP-I/-13 genes in primary inguinal hernia. BMC Med Genet 3:2 (www.​biomedcentral.​com/​1471- 2350/3/2)
7.
go back to reference Heniford BT, Park A, Ramshaw BJ, Voeller G (2003) Laparoscopic repair of ventral hernias. Nine years experience with 850 consecutive hernias. Ann Surg 238(3):391–400 Heniford BT, Park A, Ramshaw BJ, Voeller G (2003) Laparoscopic repair of ventral hernias. Nine years experience with 850 consecutive hernias. Ann Surg 238(3):391–400
8.
go back to reference Askar OM (1977) Surgical anatomy of the aponeurotic expansions of the anterior abdominal wall. Ann R Coll Sur Engl 59(4):313–321 Askar OM (1977) Surgical anatomy of the aponeurotic expansions of the anterior abdominal wall. Ann R Coll Sur Engl 59(4):313–321
9.
go back to reference Askar OM (1978) A new concept of the aetiology and surgical repair of paraumbilical and epigastric hernias. Ann R Coll Surg Engl (60):42–48 Askar OM (1978) A new concept of the aetiology and surgical repair of paraumbilical and epigastric hernias. Ann R Coll Surg Engl (60):42–48
10.
go back to reference Askar OM (1984) Aponeurotic hernias. Recent observations upon paraumbilical and epigastric hernias. Surg Clin North Am 64:315–333 Askar OM (1984) Aponeurotic hernias. Recent observations upon paraumbilical and epigastric hernias. Surg Clin North Am 64:315–333
12.
go back to reference Paes TR, NG T, Stoken DL, Morecroft J (1987) Circumumbilibal versus transumbilical abdominal incision. Br J Surg 74(9):822–824PubMedCrossRef Paes TR, NG T, Stoken DL, Morecroft J (1987) Circumumbilibal versus transumbilical abdominal incision. Br J Surg 74(9):822–824PubMedCrossRef
13.
14.
go back to reference Klinge U, Binnebosel M, Rosch R, Mertens P (2002) Hernia recurrence as a problem of biology and collagen. JAMA 288(3):321–333.l Klinge U, Binnebosel M, Rosch R, Mertens P (2002) Hernia recurrence as a problem of biology and collagen. JAMA 288(3):321–333.l
15.
go back to reference Casanova AB, Trindade EN, Trindade MRM (2009) Collagen in the transversalis fascia of patients with indirect inguinal hernia: a case-control study. Am J Surg 198(1):1–5PubMedCrossRef Casanova AB, Trindade EN, Trindade MRM (2009) Collagen in the transversalis fascia of patients with indirect inguinal hernia: a case-control study. Am J Surg 198(1):1–5PubMedCrossRef
16.
go back to reference Fachinelli A, Trindade MRM (2007) Qualitative evaluation of total, types I and III collagens in patients with ventral hernias. Langenbecks Arch Surg 392(4):459–464PubMedCrossRef Fachinelli A, Trindade MRM (2007) Qualitative evaluation of total, types I and III collagens in patients with ventral hernias. Langenbecks Arch Surg 392(4):459–464PubMedCrossRef
17.
go back to reference Borges LF, Taboga SR, Gutierrez PS (2005) Simultaneous observation of collagen and elastin in normal and pathological tissues: analysis of Sirius-red-stained sections by fluorescence microscopy. Cell Tissue Res 320(3):551–552PubMedCrossRef Borges LF, Taboga SR, Gutierrez PS (2005) Simultaneous observation of collagen and elastin in normal and pathological tissues: analysis of Sirius-red-stained sections by fluorescence microscopy. Cell Tissue Res 320(3):551–552PubMedCrossRef
18.
go back to reference Midwood KS, Schwarzbauer JE (2002) Elastic fibers: building bridges between cells and their matrix. Curr Biol 12(8):R279–281 Midwood KS, Schwarzbauer JE (2002) Elastic fibers: building bridges between cells and their matrix. Curr Biol 12(8):R279–281
19.
go back to reference Henwood A (2003) Current applications of orcein in histochemistry. A brief review with some new observations concerning influence of dye batch variation and aging of dye solutions on staining. Biotech Histochem 78(6):303–308 Henwood A (2003) Current applications of orcein in histochemistry. A brief review with some new observations concerning influence of dye batch variation and aging of dye solutions on staining. Biotech Histochem 78(6):303–308
20.
go back to reference Czirok A, Zach J, Kozel BA, Mecham RP, Davis EC, Rongish BJ (2006) Elastic fiber macro-assembly is a hierarchical, cell motion-mediated process. J Cell Physiol 207(1):97–106PubMedCrossRef Czirok A, Zach J, Kozel BA, Mecham RP, Davis EC, Rongish BJ (2006) Elastic fiber macro-assembly is a hierarchical, cell motion-mediated process. J Cell Physiol 207(1):97–106PubMedCrossRef
21.
go back to reference Zheng Q, Choi J, Rouleau L, Leask RL, Richardson JA, Davis EC, Yanagisawa H (2006) Normal wound healing in mice deficient for fibulin-5, an elastin binding protein essential for dermal elastic fiber assembly. J Invest Dermatol 126(12):2707–2714PubMedCrossRef Zheng Q, Choi J, Rouleau L, Leask RL, Richardson JA, Davis EC, Yanagisawa H (2006) Normal wound healing in mice deficient for fibulin-5, an elastin binding protein essential for dermal elastic fiber assembly. J Invest Dermatol 126(12):2707–2714PubMedCrossRef
22.
go back to reference Ushiki T (2002) Collagen fibers, reticular fibers and elastic fibers. A comprehensive understanding from a morphological viewpoint. Arch Histol Cytol 65(2):109–126PubMedCrossRef Ushiki T (2002) Collagen fibers, reticular fibers and elastic fibers. A comprehensive understanding from a morphological viewpoint. Arch Histol Cytol 65(2):109–126PubMedCrossRef
23.
go back to reference Rodrigues Junior AJ, Rodrigues CJ, da Cunha AC, Jin Y (2002) Quantitative analysis of collagen and elastic fibers in the transversalis fascia in direct and indirect inguinal hernia. Rev Hosp Clin Fac Med Sao Paulo 57(6):265–270PubMed Rodrigues Junior AJ, Rodrigues CJ, da Cunha AC, Jin Y (2002) Quantitative analysis of collagen and elastic fibers in the transversalis fascia in direct and indirect inguinal hernia. Rev Hosp Clin Fac Med Sao Paulo 57(6):265–270PubMed
24.
go back to reference Curci JA, Melman LM, Thompson RW, Soper NJ, Matthews BD (2008) Elastic fiber depletion in the supporting ligaments of the gastroesophageal junction: a structural basis for the development of hiatal hernia. J Am Coll Surg 207(2):191–196PubMedCrossRef Curci JA, Melman LM, Thompson RW, Soper NJ, Matthews BD (2008) Elastic fiber depletion in the supporting ligaments of the gastroesophageal junction: a structural basis for the development of hiatal hernia. J Am Coll Surg 207(2):191–196PubMedCrossRef
25.
go back to reference Matar ZS (2008) Open surgical management of incisional hernia. Internet J Surg 15(2) Matar ZS (2008) Open surgical management of incisional hernia. Internet J Surg 15(2)
26.
go back to reference Togo S, Nagano Y, Masumoto C, Takakura H, Matsuo K, Takeda K, Endo I, Shimada H (2008) Outcome of and risk factors for incisional hernia after partial hepatectomy. J Gastrointest Surg 12:1115–1120PubMedCrossRef Togo S, Nagano Y, Masumoto C, Takakura H, Matsuo K, Takeda K, Endo I, Shimada H (2008) Outcome of and risk factors for incisional hernia after partial hepatectomy. J Gastrointest Surg 12:1115–1120PubMedCrossRef
27.
go back to reference Sugerman HJ, Kellum JM Jr, Reines HD, DeMaria EJ, Newsome HH, Lowry JW (1996) Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh. Am J Surg 171(1):80–84PubMedCrossRef Sugerman HJ, Kellum JM Jr, Reines HD, DeMaria EJ, Newsome HH, Lowry JW (1996) Greater risk of incisional hernia with morbidly obese than steroid-dependent patients and low recurrence with prefascial polypropylene mesh. Am J Surg 171(1):80–84PubMedCrossRef
28.
go back to reference Sauerland S, Korenkov M, Kleinen T, Arndt M, Paul A (2004) Obesity is a risk factor for recurrence after incisional hernia repair. Hernia 8:42–46PubMedCrossRef Sauerland S, Korenkov M, Kleinen T, Arndt M, Paul A (2004) Obesity is a risk factor for recurrence after incisional hernia repair. Hernia 8:42–46PubMedCrossRef
29.
go back to reference Maleszewski J, Lu J, Fox-Talbot K et al (2007) Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis. J Histochem Cytochem 55:597–606PubMedCrossRef Maleszewski J, Lu J, Fox-Talbot K et al (2007) Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis. J Histochem Cytochem 55:597–606PubMedCrossRef
30.
go back to reference Rudman D (1985) Growth hormone, body composition and aging. J Am Geriatr Soc 33(11):800–807PubMed Rudman D (1985) Growth hormone, body composition and aging. J Am Geriatr Soc 33(11):800–807PubMed
31.
go back to reference Szczesny W, Cerkaska K, Tretyn A, Dabrowiecki S (2006) Etiology of inguinal hernia: ultrastructure of rectus sheath revisited. Hernia 10(3):266–271 Szczesny W, Cerkaska K, Tretyn A, Dabrowiecki S (2006) Etiology of inguinal hernia: ultrastructure of rectus sheath revisited. Hernia 10(3):266–271
32.
go back to reference Ramos HVL, Simões MJ, Pontes PAL, Neves LR, Barbosa LHF, De Biase NG, Oshima CTS (2005) Imunohistoquímica como método de estudo das fibras elásticas em prega vocal humana. Rev Bras Otorrinolaringol 71(4):486–491 Ramos HVL, Simões MJ, Pontes PAL, Neves LR, Barbosa LHF, De Biase NG, Oshima CTS (2005) Imunohistoquímica como método de estudo das fibras elásticas em prega vocal humana. Rev Bras Otorrinolaringol 71(4):486–491
33.
go back to reference Ito I, Imada M, Ikeda M, Sueno K, Arikuni T, Kida A (2001) A morphological study of age changes in adult human auricular cartilage with special emphasis on elastic fibers. Laryngoscope 111(5): 881–886 Ito I, Imada M, Ikeda M, Sueno K, Arikuni T, Kida A (2001) A morphological study of age changes in adult human auricular cartilage with special emphasis on elastic fibers. Laryngoscope 111(5): 881–886
34.
go back to reference Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L (2004) Acquired disorders of elastic tissue: Part II. Decreased elastic tissue. J Am Acad Dermatol 51(2):165–185 Lewis KG, Bercovitch L, Dill SW, Robinson-Bostom L (2004) Acquired disorders of elastic tissue: Part II. Decreased elastic tissue. J Am Acad Dermatol 51(2):165–185
Metadata
Title
Elastic fibers in the anterior abdominal wall
Authors
A. Fachinelli
M. R. M. Trindade
F. A. Fachinelli
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
Hernia / Issue 4/2011
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-011-0804-2

Other articles of this Issue 4/2011

Hernia 4/2011 Go to the issue