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Archives of Virology
Published in: Archives of Virology 4/2020

01-04-2020 | Human Immunodeficiency Virus | Brief Report

The emergence of an unassigned complex recombinant form in a Pakistani HIV-infected individual

Authors: Uroosa Tariq, Ayesha Iftikhar, Dilsha Zahid, Faisal Sultan, Syed Faisal Mahmood, Sadaf Naeem, Syed Ali, Syed Hani Abidi

Published in: Archives of Virology | Issue 4/2020

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Abstract

In Pakistan, the HIV situation has gone from an outbreak to a concentrated epidemic, and the virus has now crossed into the low-risk population. In addition, several new HIV outbreaks have occurred in different parts of the country. HIV-1 subtype A has been the major epidemic subtype in Pakistan; however, as the epidemic has grown, the emergence of several new subtypes and recombinant forms has been observed. Here, we present the first case and genetic analysis of an unassigned, complex recombinant form in a Pakistani HIV-infected individual with virological failure. Genetic analysis of the sequence indicated that this recombinant form is multi-drug resistant, harboring drug resistance mutations against more than one class of antiretroviral drugs.
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Metadata
Title
The emergence of an unassigned complex recombinant form in a Pakistani HIV-infected individual
Authors
Uroosa Tariq
Ayesha Iftikhar
Dilsha Zahid
Faisal Sultan
Syed Faisal Mahmood
Sadaf Naeem
Syed Ali
Syed Hani Abidi
Publication date
01-04-2020
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 4/2020
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-020-04551-4

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