Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Archives of Virology
Published in: Archives of Virology 7/2013

01-07-2013 | Original Article

Phylogenetic analysis of two Chinese orf virus isolates based on sequences of B2L and VIR genes

Authors: Huixia Li, Xueliang Zhu, Yadong Zheng, Shuai Wang, Zhenyong Liu, Yongxi Dou, Hui Li, Xuepeng Cai, Xuenong Luo

Published in: Archives of Virology | Issue 7/2013

Login to get access

Abstract

Orf virus (ORFV) is an enveloped virus with a double-stranded DNA genome, causing a contagious pustular dermatitis, mainly in goats and sheep. In this study, two strains of ORFV were isolated from sheep and goat samples in Xinjiang and Shaanxi, China. The B2L and virus interferon resistance (VIR) genes of these two isolates were sequenced and analyzed after PCR amplification. Phylogenetic analysis showed that the two isolates clustered with other ORFV strains but were separated into different subgroups. The Xinjiang strain shared the highest homology with the Gansu strain, whereas the Shaanxi strain shared higher homology with the Taiwan and Hubei strains. This is the first report of the molecular characterization of ORFV in Northwest China, and it provides new information on the genotyping of the causative agents responsible for contagious ecthyma dermatitis outbreaks in China.
Literature
1.
Nandi S, De UK, Chowdhury S (2011) Current status of contagious ecthyma or orf disease in goat and sheep-A global perspective. Small Ruminant Res 96:73–82CrossRef
2.
Hosamani M, Bhanuprakash V, Scagliarini A, Singh RK (2006) Comparative sequence analysis of major envelope protein gene (B2L) of Indian orf viruses isolated from sheep and goats. Vet Microbiol 116:317–324PubMedCrossRef
3.
Ara M, Zaballos P, Sanchez M, Querol I, Zubiri ML, Simal E, Horndler C (2008) Giant and recurrent orf virus infection in a renal transplant recipient treated with imiquimod. J Am Acad Dermatol 58:S39–S40PubMedCrossRef
4.
Zhao K, Song DG, He WQ, Lu HJ, Zhang BB, Li C, Chen KY, Gao F (2010) Identification and phylogenetic analysis of an Orf virus isolated from an outbreak in sheep in the Jilin province of China. Vet Microbiol 142:408–415PubMedCrossRef
5.
Haig DM, McInnes CJ (2002) Immunity and counter-immunity during infection with the parapoxvirus orf virus. Virus Res 88:3–16PubMedCrossRef
6.
Delhon G, Tulman ER, Afonso CL, Lu Z, de la Concha-Bermejillo A, Lehmkuhl HD, Piccone ME, Kutish GF, Rock DL (2004) Genomes of the parapoxviruses orf virus and bovine Papular stomatitis virus. J Virol 78:168–177PubMedCrossRef
7.
Sullivan JT, Mercer AA, Fleming SB, Robinson AJ (1994) Identification and characterization of an orf virus homologue of the vaccinia virus gene encoding the major envelope antigen p37 K. Virology 202:968–973PubMedCrossRef
8.
Inoshima Y, Morooka A, Sentsui H (2000) Detection and diagnosis of parapoxvirus by the polymerase chain reaction. J Virol Methods 84:201–208PubMedCrossRef
9.
Inoshima Y, Murakami K, Yokoyama T, Sentsui H (2001) Genetic heterogeneity among parapoxviruses isolated from sheep, cattle and Japanese serows (Capricornis crispus). J Gen Virol 82:1215–1220PubMed
10.
Tikkanen MK, McInnes CJ, Mercer AA, Buttner M, Tuimala J, Hirela-Koski V, Neuvonen E, Huovilainen A (2004) Recent isolates of Parapoxvirus of Finnish reindeer (Rangifer tarandus tarandus) are closely related to bovine Pseudocowpox virus. J Gen Virol 85:1413–1418PubMedCrossRef
11.
Zhang K, Shang Y, Jin Y, Wang G, Zheng H, He J, Lu Z, Liu X (2010) Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report. Virol J 7:78–82PubMedCrossRef
12.
McInnes CJ, Wood AR, Mercer AA (1998) Orf virus encodes a homolog of the vaccinia virus interferon resistance gene E3L. Virus Genes 17:107–115PubMedCrossRef
13.
Kottaridi C, Nomikou K, Teodori L, Savini G, Lelli R, Markoulatos P, Mangana O (2006) Phylogenetic correlation of Greek and Italian orf virus isolates based on VIR gene. Vet Microbiol 116:310–316PubMedCrossRef
14.
Oem JK, Roh IS, Lee KH, Lee KK, Kim HR, Jean YH, Lee OS (2009) Phylogenetic analysis and characterization of Korean orf virus from dairy goats: case report. Virol J 6:167
15.
Kottaridi C, Nomikou K, Lelli R, Markoulatos P, Mangana O (2006) Laboratory diagnosis of contagious ecthyma: comparison of different PCR protocols with virus isolation in cell culture. J Virol Methods 134:119–124PubMedCrossRef
16.
Torfason EG, Guonadottir S (2002) Polymerase chain reaction for laboratory diagnosis of orf virus infections. J Clin Virol 24:79–84PubMedCrossRef
17.
Liu Y, Shao H, Cheng R (2007) Establish and application of PCR detection method to contagious pustular dermatitis virus. Jilin Xu Mu Shou Yi 3:7–9
18.
Chan KW, Lin JW, Lee SH, Liao CJ, Tsai MC, Hsu WL, Wong ML, Shih HC (2007) Identification and phylogenetic analysis of orf virus from goats in Taiwan. Virus Genes 35:705–712
19.
Chan KW, Yang CH, Lin JW, Wang HC, Lin FY, Kuo ST, Wong ML, Hsu WL (2009) Phylogenetic analysis of parapoxviruses and the C-terminal heterogeneity of viral ATPase proteins. Gene 432:44–53
20.
Lucinda N, Inoue-Nagata AK, Kitajima EW, Nagata T (2010) Complete genome sequence of Brugmansia suaveolens mottle virus, a potyvirus from an ornamental shrub. Arch Virol 155(10):1729–1732
21.
Mercer AA, Ueda N, Friederichs SM, Hofmann K, Fraser KM, Bateman T, Fleming SB (2006) Comparative analysis of genome sequences of three isolates of orf virus reveals unexpected sequence variation. Virus Res. 116(1–2):146–158
22.
Guo J, Zhang Z, Edwards JF, Ermel RW, Taylor C Jr, de la Concha-Bermejillo A (2003) Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis. Virus Res. 93:169–179
23.
Guo J, Rasmussen J, Wunschmann A, de la Concha-Bermejillo A (2004) Genetic characterization of orf viruses isolated from various ruminant species of a zoo. Vet Microbiol 99:81–92
24.
Hautaniemi M, Ueda N, Tuimala J, Mercer AA, Lahdenpera J, McInnes CJ (2010) The genome of pseudocowpoxvirus: comparison of a reindeer isolate and a reference strain. J Gen Virol 91(6):1560–1576
25.
Inoshima Y, Ito M, Ishiguro N (2010) Spatial and temporal genetic homogeneity of orf viruses infecting Japanese serows (Capricornis crispus). J Vet Med Sci 72(6):701–707
Metadata
Title
Phylogenetic analysis of two Chinese orf virus isolates based on sequences of B2L and VIR genes
Authors
Huixia Li
Xueliang Zhu
Yadong Zheng
Shuai Wang
Zhenyong Liu
Yongxi Dou
Hui Li
Xuepeng Cai
Xuenong Luo
Publication date
01-07-2013
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 7/2013
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-013-1641-7

Other articles of this Issue 7/2013

Archives of Virology 7/2013 Go to the issue

Brief Report

Prevalence and molecular characterization of porcine enteric caliciviruses and first detection of porcine kobuviruses in US swine

Original Article

Molecular epidemiology and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea

Original Article

A consensus envelope protein domain III can induce neutralizing antibody responses against serotype 2 of dengue virus in non-human primates

Annotated Sequence Record

Molecular characterization of a novel monopartite begomovirus isolated from Pouzolzia zeylanica in China

Brief Report

Construction of an infectious cDNA clone of radish mosaic virus, a crucifer-infecting comovirus

Brief Report

Genetic characterization of betanodavirus isolates from Asian seabass Lates calcarifer (Bloch) in India
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Heart Failure Video

Year in Review: Heart failure and cardiomyopathies

Watch now

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits