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01-09-2009 | Biological Psychiatry - Short Communication

Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in borderline personality disorder

Authors: André Tadić, Amelie Elsäßer, Anja Victor, Robert von Cube, Ömür Başkaya, Stefanie Wagner, Klaus Lieb, Wolfgang Höppner, Norbert Dahmen

Published in: Journal of Neural Transmission | Issue 9/2009

Abstract

The purpose of this study was to test for association between Borderline personality disorder (BPD) and variants of the HTR1B and the brain-derived neurotrophic factor (BDNF) gene. We genotyped four HTR1B and the functional BDNF G196A marker in 161 Caucasian BPD patients and 156 healthy controls. There were no significant differences between groups in genotype or haplotype distribution of HTR1B markers or in genotype distribution of the BDNF marker. Logistic regression analyses revealed an over-representation of the BDNF 196A allele in HTR1B A-161 allele carrying BPD patients.

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Title: Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in borderline personality disorder
Authors: André Tadić
Amelie Elsäßer
Anja Victor
Robert von Cube
Ömür Başkaya
Stefanie Wagner
Klaus Lieb
Wolfgang Höppner
Norbert Dahmen
Publication date: 01-09-2009
Publisher: Springer Vienna
Published in: Journal of Neural Transmission / Issue 9/2009
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-009-0264-3

Keynote webinar | Spotlight on sleep in brain health

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Association analysis of serotonin receptor 1B (HTR1B) and brain-derived neurotrophic factor gene polymorphisms in borderline personality disorder

Abstract

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

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