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Surgery Today
Published in: Surgery Today 8/2015

01-08-2015 | Original Article

Efficacy of intraoperative HyperEye Medical System angiography for coronary artery bypass grafting

Authors: Masaki Yamamoto, Kazumasa Orihashi, Hideaki Nishimori, Takemi Handa, Nobuo Kondo, Takashi Fukutomi, Takayuki Sato

Published in: Surgery Today | Issue 8/2015

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Abstract

Purpose

When performing coronary artery bypass grafting, anastomotic insufficiency needs to be detected during surgery. We developed a novel indocyanine green angiography system, the HyperEye Medical System (HEMS), which enables color imaging of the bypass flow. This article described the accuracy of HEMS angiography for predicting graft patency.

Methods

A total of 144 grafts in 40 coronary artery bypass grafting patients were assessed by HEMS angiography, a transit time flowmeter (TTF) during surgery and fluoroscopic angiography 1 year after the operation.

Results

HEMS angiography showed normal flow in 133 grafts, but abnormal flow in 11. Fluoroscopic angiography showed that 130 of the 133 “normal” grafts were patent (negative predictive value: 97.7 %) and that nine of the 11 “abnormal” grafts were occluded (positive predictive value: 81.8 %). As a result, 134 grafts were assessed as normal and 10 as abnormal by TTF. Fluoroscopic angiography showed that 124 of these 134 grafts were patent (negative predictive value: 92.5 %), whereas two of the 10 grafts were occluded (positive predictive value: 20.0 %). For the 127 grafts with compatible results by the HEMS and TTF assessments, the positive and negative predictive values were 100 and 97.6 %, respectively.

Conclusion

HEMS angiography of a bypass graft may provide an accurate prediction of the graft patency after surgery.
Literature
1.
Sakata R, Fujii Y, Kuwano H. Thoracic and cardiovascular surgery in Japan during 2009: annual report by the Japanese Association For Thoracic Surgery. Gen Thorac Cardiovasc Surg. 2011;59:636–67.PubMedCrossRef
2.
Khan NE, De Souza A, Mister R, Flather M, Clague J, Davies S, et al. A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery. N Engl J Med. 2004;350:21–8.PubMedCrossRef
3.
D’Ancona G, Bartolozzi F, Bogers AJ, Pilato M, Parrinello M, Kappetein AP. Intraoperative graft patency verification in coronary artery surgery: modern diagnostic tools. J Cardiothorac Vasc Anesth. 2009;23:232–8.PubMedCrossRef
4.
Canver CC, Dame NA. Ultrasonic assessment of internal thoracic artery graft flow in the revascularized heart. Ann Thorac Surg. 1994;58:135–8.PubMedCrossRef
5.
Rubens FD, Ruel M, Fremes SE. A new and simplified method for coronary and graft imaging during CABG. Heart Surg Forum. 2002;5:141–4.PubMed
6.
Detter C, Russ D, Iffland A, Wipper S, Schurr MO, Reichenspurner H, et al. Near-infrared fluorescence coronary angiography: a new noninvasive technology for intraoperative graft patency control. Heart Surg Forum. 2002;5:364–9.PubMed
7.
McPherson DD, Hiratzka LF, Lamberth WC, Brandt B, Hunt M, Kieso RA, et al. Delineation of the extent of coronary atherosclerosis by high-frequency epicardial echocardiography. N Engl J Med. 1987;316:304–9.PubMedCrossRef
8.
Reuthebuch O, Haussler A, Genoni M, Tavakoli R, Odavic D, Kadner A, et al. Novadaq spy: intraoperative quality assessment in off-pump coronary artery bypass grafting. Chest. 2004;125:418–24.PubMedCrossRef
9.
Taggart DP, Choudhary B, Anastasiadis K, Abu-Omar Y, Balacumaraswami L, Pigott DW. Preliminary experience with a novel intraoperative fluorescence imaging technique to evaluate the patency of bypass grafts in total arterial revascularization. Ann Thorac Surg. 2003;75:870–3.PubMedCrossRef
10.
Handa T, Katare RG, Sasaguri S, Sato T. Preliminary experience for the evaluation of the intraoperative graft patency with real color charge-coupled device camera system: an advanced device for simultaneous capturing of color and near-infrared images during coronary artery bypass graft. Interact Cardiovasc Thorac Surg. 2009;9:150–4.PubMedCrossRef
11.
Cherrick GR, Stein SW, Leevy CM, Davidson CS. Indocyanine green: observations on its physical properties, plasma decay, and hepatic extraction. J Clin Invest. 1960;39:592–600.PubMedCentralPubMedCrossRef
12.
Yamamoto M, Sasaguri S, Sato T. Assessing intraoperative blood flow in cardiovascular surgery. Surg Today. 2011;41:1467–74.PubMedCrossRef
13.
Yamamoto M, Orihashi K, Nishimori H, Wariishi S, Fukutomi T, Kondo N, et al. Indocyanine green angiography for intra-operative assessment in vascular surgery. Eur J Vasc Endovasc Surg. 2012;43:426–32.PubMedCrossRef
14.
Desai ND, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier MP, et al. A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. J Thorac Cardiovasc Surg. 2006;132:585–94.PubMedCrossRef
15.
Balacumaraswami L, Abu-Omar Y, Choudhary B, Pigott D, Taggart DP. A comparison of transit-time flowmetry and intraoperative fluorescence imaging for assessing coronary artery bypass graft patency. J Thorac Cardiovasc Surg. 2005;130:315–20.PubMedCrossRef
16.
Handa T, Katare RG, Nishimori H, Wariishi S, Fukutomi T, Yamamoto M, et al. New device for intraoperative graft assessment: Hypereye charge-coupled device camera system. Gen Thorac Cardiovasc Surg. 58:68–77.
17.
Budde RP, Bakker PF, Grundeman PF, Borst C. High-frequency epicardial ultrasound: review of a multipurpose intraoperative tool for coronary surgery. Surg Endosc. 2009;23:467–76.PubMedCrossRef
18.
Detter C, Wipper S, Russ D, Iffland A, Burdorf L, Thein E, et al. Fluorescent cardiac imaging: a novel intraoperative method for quantitative assessment of myocardial perfusion during graded coronary artery stenosis. Circulation. 2007;116:1007–14.PubMedCrossRef
Metadata
Title
Efficacy of intraoperative HyperEye Medical System angiography for coronary artery bypass grafting
Authors
Masaki Yamamoto
Kazumasa Orihashi
Hideaki Nishimori
Takemi Handa
Nobuo Kondo
Takashi Fukutomi
Takayuki Sato
Publication date
01-08-2015
Publisher
Springer Japan
Published in
Surgery Today / Issue 8/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-014-1015-0

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