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Published in: Surgery Today 8/2015

01-08-2015 | Original Article

Impact of Surgical Infection Society/Infectious Disease Society of America-recommended antibiotics on postoperative intra-abdominal abscess with image-guided percutaneous abscess drainage following gastrointestinal surgery

Authors: Yoshiki Okita, Minako Kobayashi, Toshimitsu Araki, Hiroyuki Fujikawa, Koike Yuki, Otake Kohei, Inoue Mikihiro, Toiyama Yuji, Msaki Ohi, Koji Tanaka, Yasuhiro Inoue, Keiichi Uchida, Yasuhiko Mohri, Koichiro Yamakado, Masato Kusunoki

Published in: Surgery Today | Issue 8/2015

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Abstract

Purpose

The aims of this study were to reveal how using the antibiotics recommended by the 2010 Surgical Infection Society (SIS) and Infectious Disease Society of America (IDSA) guidelines can affect the therapeutic outcomes.

Methods

We reviewed the cases of 53 patients with a postoperative intra-abdominal abscess without anastomotic leakage after gastrointestinal surgery who underwent image-guided percutaneous abscess drainage (PAD) and concomitant antibiotic therapy. The type of antibiotic initially administered was determined based on the surgeon’s judgment. A persistent abscess was defined as one or more PAD procedures resulting in complete resolution after 21 or more days. The recommended antibiotics were defined according to 2010 SIS/IDSA guidelines.

Results

All 53 patients had complete resolution without the need for surgery. The results of a multivariable analysis revealed that a C-reactive protein level ≥12 mg/dL and non-recommended antibiotics were significant risk factors for a persistent abscess (P = 0.042 and 0.013, respectively). With regard to a fever lasting more than 48 h, there was a significant difference between the recommended (45.1 %) and non-recommended (72.7 %) antibiotic groups (P = 0.046).

Conclusions

Using the recommended antibiotics may shorten the time to defervescence and reduce the risk of a persistent abscess in patients undergoing PAD for a postoperative abscess after gastrointestinal surgery.
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Metadata
Title
Impact of Surgical Infection Society/Infectious Disease Society of America-recommended antibiotics on postoperative intra-abdominal abscess with image-guided percutaneous abscess drainage following gastrointestinal surgery
Authors
Yoshiki Okita
Minako Kobayashi
Toshimitsu Araki
Hiroyuki Fujikawa
Koike Yuki
Otake Kohei
Inoue Mikihiro
Toiyama Yuji
Msaki Ohi
Koji Tanaka
Yasuhiro Inoue
Keiichi Uchida
Yasuhiko Mohri
Koichiro Yamakado
Masato Kusunoki
Publication date
01-08-2015
Publisher
Springer Japan
Published in
Surgery Today / Issue 8/2015
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-014-1047-5

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