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01-09-2014 | Original Article

A treatment strategy for preventing pouchitis as a postoperative complication of ulcerative colitis: the significance of the management of cuffitis

Authors: Takuzo Hashimoto, Michio Itabashi, Shinpei Ogawa, Tomoichiro Hirosawa, Yoshiko Bamba, Sanae Kaji, Mamiko Ubukata, Sayumi Nakao, Shingo Kameoka

Published in: Surgery Today | Issue 9/2014

Abstract

Purpose

The aim of this study was to examine the risk factors for and to evaluate strategies for preventing pouchitis as a postoperative complication of ulcerative colitis (UC).

Methods

A total of 119 cases of UC in which restorative proctocolectomy with an ileal pouch-anal anastomosis (IPAA) was performed at our institution between 2000 and 2012 was investigated; nine patients in whom it was impossible to close the ileostomy due to an intractable anal fistula or pelvic abscess were excluded.

Results

The cumulative risk of developing pouchitis 5 years after IPAA with stoma closure was 31.0 %. Significant relationships with pouchitis were found for the surgical indication (p = 0.0126) and surgical method (p = 0.0214). A significant correlation was found between pouchitis and cuffitis. Pouchitis was significantly more common in the cases with cuffitis than in those without (p = 0.0002). There was also a significantly different cumulative incidence observed between the cases with and without cuffitis (p < 0.0001). In addition, pouchitis had a greater tendency to recur in the cases with cuffitis than in those without (p = 0.2730).

Conclusion

The cumulative incidence rate of pouchitis was 10.6 % at 1 year, 15.1 % at 2 years and 31.0 % at 5 years. Controlling cuffitis is important to prevent pouchitis.

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Title: A treatment strategy for preventing pouchitis as a postoperative complication of ulcerative colitis: the significance of the management of cuffitis
Authors: Takuzo Hashimoto
Michio Itabashi
Shinpei Ogawa
Tomoichiro Hirosawa
Yoshiko Bamba
Sanae Kaji
Mamiko Ubukata
Sayumi Nakao
Shingo Kameoka
Publication date: 01-09-2014
Publisher: Springer Japan
Published in: Surgery Today / Issue 9/2014
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-014-0974-5

ACC 2024 Congress

Springer Medicine

A treatment strategy for preventing pouchitis as a postoperative complication of ulcerative colitis: the significance of the management of cuffitis

Abstract

Purpose

Methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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