Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
European Journal of Orthopaedic Surgery & Traumatology
Published in: European Journal of Orthopaedic Surgery & Traumatology 1/2014

01-01-2014 | Original Article

The association between meniscal subluxation and cartilage degeneration

Authors: Young Rak Choi, Jae Hwa Kim, Ju Hwan Chung, Dong Hoon Lee, Keun Jung Ryu, Doo Hoe Ha, Jinmyoung Dan, Sang-Min Lee

Published in: European Journal of Orthopaedic Surgery & Traumatology | Issue 1/2014

Login to get access

Abstract

Purpose

The menisci play a critical protective role for the knee joint through shock absorption and load distribution. We hypothesized that cartilage degeneration will be abruptly progressed if meniscal subluxation exceeds a critical point.

Methods

Of 56 cases that showed medial meniscal subluxation without cartilage degeneration of ipsilateral medial femoral condyle (MFC) on initial MRI, from January 2005 to June 2007, meniscal subluxation index (MSI), the ratio of meniscal overhang to meniscal width in mid-coronal image of initial MRI, was measured. After 2 years, 40 cases were evaluated for cartilage degeneration of ipsilateral MFC on follow-up MRI. The relationship between medial MSI on initial MRI and cartilage degeneration of MFC on follow-up MRI was analyzed. Logistic regression analysis was conducted to find a critical point of meniscal subluxation related to cartilage degeneration.

Results

Abrupt progression of cartilage degeneration was observed from which MSI was 0.38. Logistic regression showed that if MSI was at the critical point, which was 0.38 in our study, then the probability of cartilage degeneration to grade 3 or 4 after 2 years was 44 %. If MSI was 0.4, then the probability was 50 %. If MSI was 0.6, then the probability was 99 %.

Conclusions

The results suggest the existence of critical point from which the protective function of the meniscus appears to be significantly altered, and the degree of cartilage degeneration of ipsilateral femoral condyle corresponding to the amount of medial meniscal subluxation may be predictable.
Literature
1.
Brandt K, Lohmander L, Doherty M (1998) The concept of osteoarthritis as failure of the diarthrodial joint. Osteoarthritis, Oxford University Press, Oxford, pp 70–74
2.
Biswal S, Hastie T, Andriacchi T, Bergman G, Dillingham M, Lang P (2002) Risk factors for progressive cartilage loss in the knee. Arthritis Rheum 46–11:2884–2892CrossRef
3.
Hunter D (2009) Risk stratification for knee osteoarthritis progression: a narrative review. Osteoarthr Cartil 17–11:1402–1407CrossRef
4.
Englund M (2009) The role of the meniscus in osteoarthritis genesis. Med Clin North Am 93–1:37–43CrossRef
5.
Hunter D, Zhang Y, Niu J, Tu X, Amin S, Clancy M, Guermazi A, Grigorian M, Gale D, Felson D (2006) The association of meniscal pathologic changes with cartilage loss in symptomatic knee osteoarthritis. Arthritis Rheum 54–3:795–801CrossRef
6.
Bhattacharyya T, Gale D, Dewire P, Totterman S, Gale M, McLaughlin S, Einhorn T, Felson D (2003) The clinical importance of meniscal tears demonstrated by magnetic resonance imaging in osteoarthritis of the knee. J Bone Joint Surg 85–1:4
7.
Walker P, Erkiuan M (1975) The role of the menisci in force transmission across the knee. Clin Orthop Relat Res 109:184PubMedCrossRef
8.
Yang A, Yang S, Greif W (1993) Role of meniscal subluxation in degenerative arthritis of the knee: demonstration with coronal MR imaging and the Oreo cookie model. Radiol Suppl 189:380
9.
Crema MD, Guermazi A, Li L, Nogueira-Barbosa MH, Marra MD, Roemer FW, Eckstein F, Le Graverand MP, Wyman BT, Hunter DJ (2010) The association of prevalent meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period. Osteoarthr Cartil 18(3):336–343
10.
Berthiaume MJ, Raynauld JP, Martel-Pelletier J, Labonté F, Beaudoin G, Bloch DA, Choquette D, Haraoui B, Altman RD, Hochberg M, Meyer JM, Cline GA, Pelletier JP (2005) Meniscal tear and extrusion are strongly associated with progression of symptomatic knee osteoarthritis as assessed by quantitative magnetic resonance imaging. Ann Rheum Dis 64(4):556–563
11.
Shelbourne K, Carr D (2003) Meniscal repair compared with meniscectomy for bucket-handle medial meniscal tears in anterior cruciate ligament-reconstructed knees. Am J Sports Med 31–5:718
12.
Kenny C (1997) Radial displacement of the medial meniscus and Fairbank’s signs. Clin Orthop Relat Res 339:163PubMedCrossRef
13.
Ding C, Garnero P, Cicuttini F, Scott F, Cooley H, Jones G (2005) Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown. Osteoarthr Cartil 13–3:198–205CrossRef
14.
Bessette G (1992) The meniscus. Orthopedics 15–1:35
15.
Vedi V, Spouse E, Williams A, Tennant S, Hunt D, Gedroyc W (1999) Meniscal movement: an in vivo study using dynamic MRI. J Bone Joint Surg Br 81–1:37CrossRef
16.
Muratsu H, Ishimoto K, Kurosaka M, Yoshiya S, Mizuno K (2000) The mechanical mapping of the meniscus. In: 46th annual meeting, Orthopaedic Research Society, March 12-15. Orlando, Florida
17.
Fithian D, Kelly M, Mow V (1990) Material properties and structure-function relationships in the menisci. Clin Orthop Relat Res 252:19PubMed
18.
Lerer D, Umans H, Hu M, Jones M (2004) The role of meniscal root pathology and radial meniscal tear in medial meniscal extrusion. Skeletal Radiol 33–10:569–574
19.
Stärke C, Kopf S, Gröbel KH, Becker R (2010) The effect of a nonanatomic repair of the meniscal horn attachment on meniscal tension: a biomechanical study. Arthrosc 26(3):358–365
20.
Gale D, Chaisson C, Totterman S, Schwartz R, Gale M, Felson D (1999) Meniscal subluxation: association with osteoarthritis and joint space narrowing. Osteoarthr Cartil 7–6:526–532CrossRef
21.
Lo G, Hunter D, Nevitt M, Lynch J, McAlindon T (2009) Strong association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthr Cartil 17–6:743–747CrossRef
22.
Ding C, Martel-Pelletier J, Pelletier J, Abram F, Raynauld J, Cicuttini F, Jones G (2007) Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume. Arthritis Res Ther 9–2:R21CrossRef
23.
Mow V, Kuei S, Lai W, Armstrong C (1980) Biphasic creep and stress relaxation of articular cartilage in compression: theory and experiments. J Biomech Eng 102:73PubMedCrossRef
24.
Favenesi J, Shaffer J, Mow V (1983) Biphasic mechanical properties of knee meniscus. Trans Orthop Res Soc 8:57
25.
Spilker R, Donzelli P, Mow V (1992) A transversely isotropic biphasic finite element model of the meniscus. J Biomech 25–9:1027–1045CrossRef
26.
Boxheimer L, Lutz A, Treiber K, Goepfert K, Crook D, Marincek B, Weishaupt D (2004) MR imaging of the knee: position related changes of the menisci in asymptomatic volunteers. Invest Radiol 39–5:254CrossRef
Metadata
Title
The association between meniscal subluxation and cartilage degeneration
Authors
Young Rak Choi
Jae Hwa Kim
Ju Hwan Chung
Dong Hoon Lee
Keun Jung Ryu
Doo Hoe Ha
Jinmyoung Dan
Sang-Min Lee
Publication date
01-01-2014
Publisher
Springer Paris
Published in
European Journal of Orthopaedic Surgery & Traumatology / Issue 1/2014
Print ISSN: 1633-8065
Electronic ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-012-1144-3

Other articles of this Issue 1/2014

European Journal of Orthopaedic Surgery & Traumatology 1/2014 Go to the issue

General Review

The sound of orthopaedic surgery—the application of acoustic emission technology in orthopaedic surgery: a review

Original Article

Anatomy of the clavicle and its medullary canal: a computed tomography study

Original Article

The options of the three different surgical approaches for the treatment of Denis type A and B thoracolumbar burst fracture

Original Article

Patella rings for treatment of patellar fracture

Original Article

The natural history of ceramic-on-ceramic prosthetic hip squeak and its impact on patients

Original Article

Reverse pedicle-based greater saphenous neuro-veno-fasciocutaneous flap for reconstruction of lower leg and foot