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European Spine Journal
Published in: European Spine Journal 7/2019

01-07-2019 | Original Article

Analysis of skeletal muscle mass in women over 40 with degenerative lumbar scoliosis

Authors: Yawara Eguchi, Toru Toyoguchi, Kazuhide Inage, Kazuki Fujimoto, Sumihisa Orita, Miyako Suzuki, Hirohito Kanamoto, Koki Abe, Masaki Norimoto, Tomotaka Umimura, Takashi Sato, Masao Koda, Takeo Furuya, Yasuchika Aoki, Junichi Nakamura, Tsutomu Akazawa, Kazuhisa Takahashi, Seiji Ohtori

Published in: European Spine Journal | Issue 7/2019

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Abstract

Purpose

We investigated the involvement of sarcopenia in middle-aged and elderly women with degenerative lumbar scoliosis (DLS).

Methods

A total of 971 women (mean age 70.4 years) were included in our study. These included 87 cases of DLS (mean 73.8 years) and 884 controls (69.8). Lumbar and femur BMD was measured for all participants using dual-energy X-ray absorptiometry. We used a bioelectrical impedance analyzer to analyze body composition, including appendicular skeletal muscle mass index (SMI; appendicular lean mass (kg)/(height (m))2. We determined bone density and skeletal muscle mass in both groups and determined the prevalence of sarcopenia. We examined the correlation between bone density and appendicular muscle mass in both groups. We also examined factors related to scoliosis using logistic regression analysis.

Results

The DLS group showed significantly higher lumbar BMD, lower femur BMD, lower lean mass arm, and lower lean mass leg, and lower lean mass trunk (p < 0.05). Sarcopenia prevalence (SMI < 5.75) was 59.8% in DLS subjects and 42.8% in controls, revealing a high prevalence in DLS (p < 0.05). In both groups, lumbar and femur BMD were positively correlated with appendicular muscle mass. By logistic regression analysis, trunk muscle mass was detected as a risk factor for DLS independent of age (p < 0.05).

Conclusions

In middle-aged and elderly women, prevalence of sarcopenia was 59.8% in DLS cases and 42.8% in controls, which revealed a high prevalence in DLS. A decrease in trunk muscle was a significant risk factor for DLS that was independent of age.

Graphical abstract

These slides can be retrieved under Electronic Supplementary Material.
Appendix
Available only for authorised users
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Metadata
Title
Analysis of skeletal muscle mass in women over 40 with degenerative lumbar scoliosis
Authors
Yawara Eguchi
Toru Toyoguchi
Kazuhide Inage
Kazuki Fujimoto
Sumihisa Orita
Miyako Suzuki
Hirohito Kanamoto
Koki Abe
Masaki Norimoto
Tomotaka Umimura
Takashi Sato
Masao Koda
Takeo Furuya
Yasuchika Aoki
Junichi Nakamura
Tsutomu Akazawa
Kazuhisa Takahashi
Seiji Ohtori
Publication date
01-07-2019
Publisher
Springer Berlin Heidelberg
Published in
European Spine Journal / Issue 7/2019
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-018-5845-0

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