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Published in: Journal of Anesthesia 4/2020

01-08-2020 | Ultrasound | Original Article

Incidence of hemi-diaphragmatic paresis after ultrasound-guided intermediate cervical plexus block: a prospective observational study

Authors: Ha Yeon Kim, Euy Young Soh, Jeonghun Lee, Sei Hyuk Kwon, Min Hur, Sang-Kee Min, Jin-Soo Kim

Published in: Journal of Anesthesia | Issue 4/2020

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Abstract

Purpose

An intermediate cervical plexus block (CPB) targets the posterior cervical space between the sternocleidomastoid muscle and the prevertebral fascia. The phrenic nerve descends obliquely on the surface of the anterior scalene muscle beneath the prevertebral fascia after originating from the C3–C5 ventral rami. Therefore, the phrenic nerve can be affected by a local anesthetic during an intermediate CPB, depending on the permeability characteristics of the prevertebral fascia. This study investigated whether an intermediate CPB affects the phrenic nerve, inducing hemidiaphragmatic paresis.

Methods

In this prospective observational study, 20 patients undergoing single-incision transaxillary robot-assisted right thyroidectomy were enrolled. The intermediate CPB (0.25% ropivacaine 0.2 ml/kg) was performed at the C4–5 intervertebral level carefully, without penetrating the prevertebral fascia, before the patient emerged from general anesthesia. Diaphragmatic motions of the block side were measured by M-mode ultrasonography at three time points: before anesthesia (baseline) and at 30 and 60 min after the intermediate CPB. Hemidiaphragmatic paresis was divided into three grades, depending on the percentage of diaphragm movement compared to the baseline: none (> 75%), partial paresis (25–75%), and complete paresis (< 25%).

Results

No patient showed any partial or complete ipsilateral hemidiaphragmatic paresis within 60 min after the intermediate CPB.

Conclusion

Intermediate CPB using 0.2 ml/kg of 0.25% ropivacaine at the C4–5 intervertebral level did not cause ipsilateral hemidiaphragmatic paresis. This may imply that the effect of the intermediate CPB on the phrenic nerve is not significant.
Literature
1.
go back to reference Guidera AK, Dawes PJ, Fong A, Stringer MD. Head and neck fascia and compartments: no space for spaces. Head Neck. 2014;36:1058–68.CrossRef Guidera AK, Dawes PJ, Fong A, Stringer MD. Head and neck fascia and compartments: no space for spaces. Head Neck. 2014;36:1058–68.CrossRef
2.
go back to reference Choquet O, Dadure C, Capdevila X. Ultrasound-guided deep or intermediate cervical plexus block: the target should be the posterior cervical space. Anesth Analg. 2010;111:1563–4 (author reply 4–5).CrossRef Choquet O, Dadure C, Capdevila X. Ultrasound-guided deep or intermediate cervical plexus block: the target should be the posterior cervical space. Anesth Analg. 2010;111:1563–4 (author reply 4–5).CrossRef
3.
go back to reference Balaban O, Dulgeroglu TC, Aydin T. Ultrasound-guided combined interscalene-cervical plexus block for surgical anesthesia in clavicular fractures: a retrospective observational study. Anesthesiol Res Pract. 2018;2018:7842128.PubMedPubMedCentral Balaban O, Dulgeroglu TC, Aydin T. Ultrasound-guided combined interscalene-cervical plexus block for surgical anesthesia in clavicular fractures: a retrospective observational study. Anesthesiol Res Pract. 2018;2018:7842128.PubMedPubMedCentral
4.
go back to reference Urmey WF, Talts KH, Sharrock NE. One hundred percent incidence of hemidiaphragmatic paresis associated with interscalene brachial plexus anesthesia as diagnosed by ultrasonography. Anesth Analg. 1991;72:498–503.CrossRef Urmey WF, Talts KH, Sharrock NE. One hundred percent incidence of hemidiaphragmatic paresis associated with interscalene brachial plexus anesthesia as diagnosed by ultrasonography. Anesth Analg. 1991;72:498–503.CrossRef
5.
go back to reference Castresana MR, Masters RD, Castresana EJ, Stefansson S, Shaker IJ, Newman WH. Incidence and clinical significance of hemidiaphragmatic paresis in patients undergoing carotid endarterectomy during cervical plexus block anesthesia. J Neurosurg Anesthesiol. 1994;6:21–3.CrossRef Castresana MR, Masters RD, Castresana EJ, Stefansson S, Shaker IJ, Newman WH. Incidence and clinical significance of hemidiaphragmatic paresis in patients undergoing carotid endarterectomy during cervical plexus block anesthesia. J Neurosurg Anesthesiol. 1994;6:21–3.CrossRef
6.
go back to reference Emery G, Handley G, Davies MJ, Mooney PH. Incidence of phrenic nerve block and hypercapnia in patients undergoing carotid endarterectomy under cervical plexus block. Anaesth Intensive Care. 1998;26:377–81.CrossRef Emery G, Handley G, Davies MJ, Mooney PH. Incidence of phrenic nerve block and hypercapnia in patients undergoing carotid endarterectomy under cervical plexus block. Anaesth Intensive Care. 1998;26:377–81.CrossRef
7.
go back to reference Standring S. Gray's anatomy. 41st ed. London: Churchill Livingstone; 2016. p. 464. Standring S. Gray's anatomy. 41st ed. London: Churchill Livingstone; 2016. p. 464.
8.
go back to reference Canella C, Demondion X, Delebarre A, Moraux A, Cotten H, Cotten A. Anatomical study of phrenic nerve using ultrasound. Eur Radiol. 2010;20:659–65.CrossRef Canella C, Demondion X, Delebarre A, Moraux A, Cotten H, Cotten A. Anatomical study of phrenic nerve using ultrasound. Eur Radiol. 2010;20:659–65.CrossRef
9.
go back to reference Pandit JJ, Dutta D, Morris JF. Spread of injectate with superficial cervical plexus block in humans: an anatomical study. Br J Anaesth. 2003;91:733–5.CrossRef Pandit JJ, Dutta D, Morris JF. Spread of injectate with superficial cervical plexus block in humans: an anatomical study. Br J Anaesth. 2003;91:733–5.CrossRef
10.
go back to reference Seidel R, Schulze M, Zukowski K, Wree A. Ultrasound-guided intermediate cervical plexus block. Anatomical study. Anaesthesist. 2015;64:446–50.CrossRef Seidel R, Schulze M, Zukowski K, Wree A. Ultrasound-guided intermediate cervical plexus block. Anatomical study. Anaesthesist. 2015;64:446–50.CrossRef
11.
go back to reference Barone M, Diemunsch P, Baldassarre E, Oben WE, Ciarlo M, Wolter J, Albani A. Carotid endarterectomy with intermediate cervical plexus block. Tex Heart Inst J. 2010;37:297–300.PubMedPubMedCentral Barone M, Diemunsch P, Baldassarre E, Oben WE, Ciarlo M, Wolter J, Albani A. Carotid endarterectomy with intermediate cervical plexus block. Tex Heart Inst J. 2010;37:297–300.PubMedPubMedCentral
12.
go back to reference Ramachandran SK, Picton P, Shanks A, Dorje P, Pandit JJ. Comparison of intermediate vs subcutaneous cervical plexus block for carotid endarterectomy. Br J Anaesth. 2011;107:157–63.CrossRef Ramachandran SK, Picton P, Shanks A, Dorje P, Pandit JJ. Comparison of intermediate vs subcutaneous cervical plexus block for carotid endarterectomy. Br J Anaesth. 2011;107:157–63.CrossRef
13.
go back to reference Merdad M, Crawford M, Gordon K, Papsin B. Unexplained fever after bilateral superficial cervical block in children undergoing cochlear implantation: an observational study. Can J Anaesth. 2012;59:28–33.CrossRef Merdad M, Crawford M, Gordon K, Papsin B. Unexplained fever after bilateral superficial cervical block in children undergoing cochlear implantation: an observational study. Can J Anaesth. 2012;59:28–33.CrossRef
14.
go back to reference Kim JS, Lee J, Soh EY, Ahn H, Oh SE, Lee JD, Joe HB. Analgesic effects of ultrasound-guided serratus-intercostal plane block and ultrasound-guided intermediate cervical plexus block after single-incision transaxillary robotic thyroidectomy: a prospective, randomized. Control Trial Reg Anesth Pain Med. 2016;41:584–8.CrossRef Kim JS, Lee J, Soh EY, Ahn H, Oh SE, Lee JD, Joe HB. Analgesic effects of ultrasound-guided serratus-intercostal plane block and ultrasound-guided intermediate cervical plexus block after single-incision transaxillary robotic thyroidectomy: a prospective, randomized. Control Trial Reg Anesth Pain Med. 2016;41:584–8.CrossRef
15.
go back to reference Shin S, Chung WY, Jeong JJ, Kang SW, Oh YJ. Analgesic efficacy of bilateral superficial cervical plexus block in robot-assisted endoscopic thyroidectomy using a transaxillary approach. World J Surg. 2012;36:2831–7.CrossRef Shin S, Chung WY, Jeong JJ, Kang SW, Oh YJ. Analgesic efficacy of bilateral superficial cervical plexus block in robot-assisted endoscopic thyroidectomy using a transaxillary approach. World J Surg. 2012;36:2831–7.CrossRef
16.
go back to reference Matamis D, Soilemezi E, Tsagourias M, Akoumianaki E, Dimassi S, Boroli F, Richard JC, Brochard L. Sonographic evaluation of the diaphragm in critically ill patients Technique and clinical applications. Intensive Care Med. 2013;39:801–10.CrossRef Matamis D, Soilemezi E, Tsagourias M, Akoumianaki E, Dimassi S, Boroli F, Richard JC, Brochard L. Sonographic evaluation of the diaphragm in critically ill patients Technique and clinical applications. Intensive Care Med. 2013;39:801–10.CrossRef
17.
go back to reference Gerscovich EO, Cronan M, McGahan JP, Jain K, Jones CD, McDonald C. Ultrasonographic evaluation of diaphragmatic motion. J Ultrasound Med. 2001;20:597–604.CrossRef Gerscovich EO, Cronan M, McGahan JP, Jain K, Jones CD, McDonald C. Ultrasonographic evaluation of diaphragmatic motion. J Ultrasound Med. 2001;20:597–604.CrossRef
18.
go back to reference Kang RA, Chung YH, Ko JS, Yang MK, Choi DH. Reduced hemidiaphragmatic paresis with a "corner pocket" technique for supraclavicular brachial plexus block: single-center, observer-blinded, randomized controlled trial. Reg Anesth Pain Med. 2018;43:720–4.PubMed Kang RA, Chung YH, Ko JS, Yang MK, Choi DH. Reduced hemidiaphragmatic paresis with a "corner pocket" technique for supraclavicular brachial plexus block: single-center, observer-blinded, randomized controlled trial. Reg Anesth Pain Med. 2018;43:720–4.PubMed
19.
go back to reference Renes SH, Rettig HC, Gielen MJ, Wilder-Smith OH, van Geffen GJ. Ultrasound-guided low-dose interscalene brachial plexus block reduces the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med. 2009;34:498–502.CrossRef Renes SH, Rettig HC, Gielen MJ, Wilder-Smith OH, van Geffen GJ. Ultrasound-guided low-dose interscalene brachial plexus block reduces the incidence of hemidiaphragmatic paresis. Reg Anesth Pain Med. 2009;34:498–502.CrossRef
20.
go back to reference El-Boghdadly K, Chin KJ, Chan VWS. Phrenic nerve palsy and regional anesthesia for shoulder surgery: anatomical, physiologic, and clinical considerations. Anesthesiology. 2017;127:173–91.CrossRef El-Boghdadly K, Chin KJ, Chan VWS. Phrenic nerve palsy and regional anesthesia for shoulder surgery: anatomical, physiologic, and clinical considerations. Anesthesiology. 2017;127:173–91.CrossRef
21.
go back to reference Hertzog MA. Considerations in determining sample size for pilot studies. Res Nurs Health. 2008;31:180–91.CrossRef Hertzog MA. Considerations in determining sample size for pilot studies. Res Nurs Health. 2008;31:180–91.CrossRef
22.
go back to reference Stoneham MD, Wakefield TW. Acute respiratory distress after deep cervical plexus block. J Cardiothorac Vasc Anesth. 1998;12:197–8.CrossRef Stoneham MD, Wakefield TW. Acute respiratory distress after deep cervical plexus block. J Cardiothorac Vasc Anesth. 1998;12:197–8.CrossRef
23.
go back to reference Telford RJ, Stoneham MD. Correct nomenclature of superficial cervical plexus blocks. Br J Anaesth. 2004;92:775 (author reply-6).CrossRef Telford RJ, Stoneham MD. Correct nomenclature of superficial cervical plexus blocks. Br J Anaesth. 2004;92:775 (author reply-6).CrossRef
24.
go back to reference Stoneham MD, Stamou D, Mason J. Regional anaesthesia for carotid endarterectomy. Br J Anaesth. 2015;114:372–83.CrossRef Stoneham MD, Stamou D, Mason J. Regional anaesthesia for carotid endarterectomy. Br J Anaesth. 2015;114:372–83.CrossRef
25.
go back to reference Kim JS, Ko JS, Bang S, Kim H, Lee SY. Cervical plexus block. Korean J Anesthesiol. 2018;71:274–88.CrossRef Kim JS, Ko JS, Bang S, Kim H, Lee SY. Cervical plexus block. Korean J Anesthesiol. 2018;71:274–88.CrossRef
26.
go back to reference Cornish PB. Applied anatomy of cervical plexus blockade. Anesthesiology. 1999;90:1790–1.CrossRef Cornish PB. Applied anatomy of cervical plexus blockade. Anesthesiology. 1999;90:1790–1.CrossRef
27.
go back to reference Barone M, Brigand C, Sonnek T, Ramlugun D, Calon B, Rottenberg D, Diemunsch P. Intermediate cervical plexus block for cervical esophagus diverticulectomy. Acta Anaesthesiol Belg. 2015;66:59–61.PubMed Barone M, Brigand C, Sonnek T, Ramlugun D, Calon B, Rottenberg D, Diemunsch P. Intermediate cervical plexus block for cervical esophagus diverticulectomy. Acta Anaesthesiol Belg. 2015;66:59–61.PubMed
28.
go back to reference Kim JS, Joe HB, Park MC, Ahn H, Lee SY, Chae YJ. Postoperative analgesic effect of ultrasound-guided intermediate cervical plexus block on unipolar sternocleidomastoid release with myectomy in pediatric patients with congenital muscular torticollis: a prospective, randomized controlled trial. Reg Anesth Pain Med. 2018;43:634–40.CrossRef Kim JS, Joe HB, Park MC, Ahn H, Lee SY, Chae YJ. Postoperative analgesic effect of ultrasound-guided intermediate cervical plexus block on unipolar sternocleidomastoid release with myectomy in pediatric patients with congenital muscular torticollis: a prospective, randomized controlled trial. Reg Anesth Pain Med. 2018;43:634–40.CrossRef
29.
go back to reference Thawale R, Alva S, Niraj G. Ultrasound-guided intermediate cervical plexus block with depot steroids in the management of refractory neck pain secondary to cervicothoracic myofascial pain syndrome: a case series. A A Pract. 2019;13:446–9.CrossRef Thawale R, Alva S, Niraj G. Ultrasound-guided intermediate cervical plexus block with depot steroids in the management of refractory neck pain secondary to cervicothoracic myofascial pain syndrome: a case series. A A Pract. 2019;13:446–9.CrossRef
30.
go back to reference Moore DC. Regional block: a handbook for use in the clinical practice of medicine and surgery. 4th ed. Springfield: Charles C. Thomas; 1979. p. 112–122. Moore DC. Regional block: a handbook for use in the clinical practice of medicine and surgery. 4th ed. Springfield: Charles C. Thomas; 1979. p. 112–122.
31.
go back to reference Usui Y, Kobayashi T, Kakinuma H, Watanabe K, Kitajima T, Matsuno K. An anatomical basis for blocking of the deep cervical plexus and cervical sympathetic tract using an ultrasound-guided technique. Anesth Analg. 2010;110:964–8.CrossRef Usui Y, Kobayashi T, Kakinuma H, Watanabe K, Kitajima T, Matsuno K. An anatomical basis for blocking of the deep cervical plexus and cervical sympathetic tract using an ultrasound-guided technique. Anesth Analg. 2010;110:964–8.CrossRef
32.
go back to reference Tran DQ, Dugani S, Finlayson RJ. A randomized comparison between ultrasound-guided and landmark-based superficial cervical plexus block. Reg Anesth Pain Med. 2010;35:539–43.CrossRef Tran DQ, Dugani S, Finlayson RJ. A randomized comparison between ultrasound-guided and landmark-based superficial cervical plexus block. Reg Anesth Pain Med. 2010;35:539–43.CrossRef
33.
go back to reference Kang SS, Jang JS, Park JH, Hong SJ, Shin KM, Yun YJ. Unilateral phrenic nerve block guided by ultrasonography and nerve stimulator for the treatment of hiccup developed after tongue cancer operation: a case report. Korean J Anesthesiol. 2009;56:208–10.CrossRef Kang SS, Jang JS, Park JH, Hong SJ, Shin KM, Yun YJ. Unilateral phrenic nerve block guided by ultrasonography and nerve stimulator for the treatment of hiccup developed after tongue cancer operation: a case report. Korean J Anesthesiol. 2009;56:208–10.CrossRef
34.
go back to reference Renes SH, van Geffen GJ, Rettig HC, Gielen MJ, Scheffer GJ. Ultrasound-guided continuous phrenic nerve block for persistent hiccups. Reg Anesth Pain Med. 2010;35:455–7.CrossRef Renes SH, van Geffen GJ, Rettig HC, Gielen MJ, Scheffer GJ. Ultrasound-guided continuous phrenic nerve block for persistent hiccups. Reg Anesth Pain Med. 2010;35:455–7.CrossRef
35.
go back to reference Patella M, Saporito A, Mongelli F, Pini R, Inderbitzi R, Cafarotti S. Management of residual pleural space after lung resection: fully controllable paralysis of the diaphragm through continuous phrenic nerve block. J Thorac Dis. 2018;10:4883–900.CrossRef Patella M, Saporito A, Mongelli F, Pini R, Inderbitzi R, Cafarotti S. Management of residual pleural space after lung resection: fully controllable paralysis of the diaphragm through continuous phrenic nerve block. J Thorac Dis. 2018;10:4883–900.CrossRef
36.
go back to reference Alilet A, Petit P, Devaux B, Joly C, Samain E, Pili-Floury S, Besch G. Ultrasound-guided intermediate cervical block versus superficial cervical block for carotid artery endarterectomy: the randomized-controlled CERVECHO trial. Anaesth Crit Care Pain Med. 2017;36:91–5.CrossRef Alilet A, Petit P, Devaux B, Joly C, Samain E, Pili-Floury S, Besch G. Ultrasound-guided intermediate cervical block versus superficial cervical block for carotid artery endarterectomy: the randomized-controlled CERVECHO trial. Anaesth Crit Care Pain Med. 2017;36:91–5.CrossRef
37.
go back to reference Madro P, Dabrowska A, Jarecki J, Garba P. Anaesthesia for carotid endarterectomy. Ultrasound-guided superficial/intermediate cervical plexus block combined with carotid sheath infiltration. Anaesthesiol Intensive Ther. 2016;48:234–8.CrossRef Madro P, Dabrowska A, Jarecki J, Garba P. Anaesthesia for carotid endarterectomy. Ultrasound-guided superficial/intermediate cervical plexus block combined with carotid sheath infiltration. Anaesthesiol Intensive Ther. 2016;48:234–8.CrossRef
38.
go back to reference Martusevicius R, Swiatek F, Joergensen LG, Nielsen HB. Ultrasound-guided locoregional anaesthesia for carotid endarterectomy: a prospective observational study. Eur J Vasc Endovasc Surg. 2012;44:27–30.CrossRef Martusevicius R, Swiatek F, Joergensen LG, Nielsen HB. Ultrasound-guided locoregional anaesthesia for carotid endarterectomy: a prospective observational study. Eur J Vasc Endovasc Surg. 2012;44:27–30.CrossRef
39.
go back to reference Kikura M, Suzuki K, Itagaki T, Takada T, Sato S. Age and comorbidity as risk factors for vocal cord paralysis associated with tracheal intubation. Br J Anaesth. 2007;98:524–30.CrossRef Kikura M, Suzuki K, Itagaki T, Takada T, Sato S. Age and comorbidity as risk factors for vocal cord paralysis associated with tracheal intubation. Br J Anaesth. 2007;98:524–30.CrossRef
Metadata
Title
Incidence of hemi-diaphragmatic paresis after ultrasound-guided intermediate cervical plexus block: a prospective observational study
Authors
Ha Yeon Kim
Euy Young Soh
Jeonghun Lee
Sei Hyuk Kwon
Min Hur
Sang-Kee Min
Jin-Soo Kim
Publication date
01-08-2020
Publisher
Springer Singapore
Published in
Journal of Anesthesia / Issue 4/2020
Print ISSN: 0913-8668
Electronic ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-020-02770-2

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