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01-05-2015 | Review

The microbiota in inflammatory bowel disease

Authors: Donal Sheehan, Carthage Moran, Fergus Shanahan

Published in: Journal of Gastroenterology | Issue 5/2015

Abstract

This review explores our current understanding of the complex interaction between environmental risk factors, genetic traits and the development of inflammatory bowel disease. The primacy of environmental risk factors is illustrated by the rapid increase in the incidence of the disease worldwide. We discuss how the gut microbiota is the proximate environmental risk factor for subsequent development of inflammatory bowel disease. The evolving fields of virome and mycobiome studies will further our understanding of the full potential of the gut microbiota in disease pathogenesis. Manipulating the gut microbiota is a promising therapeutic avenue.

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Title: The microbiota in inflammatory bowel disease
Authors: Donal Sheehan
Carthage Moran
Fergus Shanahan
Publication date: 01-05-2015
Publisher: Springer Japan
Published in: Journal of Gastroenterology / Issue 5/2015
Print ISSN: 0944-1174
Electronic ISSN: 1435-5922
DOI: https://doi.org/10.1007/s00535-015-1064-1

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ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

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