Skip to main content
Top
Published in: Journal of Hepato-Biliary-Pancreatic Sciences 2/2013

01-02-2013 | Topics

Gas embolism in laparoscopic hepatectomy: what is the optimal pneumoperitoneal pressure for laparoscopic major hepatectomy?

Authors: Yuichiro Otsuka, Toshio Katagiri, Jun Ishii, Tetsuya Maeda, Yoshihisa Kubota, Akira Tamura, Masaru Tsuchiya, Hironori Kaneko

Published in: Journal of Hepato-Biliary-Pancreatic Sciences | Issue 2/2013

Login to get access

Abstract

Laparoscopic hepatectomy (LH) has become popular as a surgical treatment for liver diseases, and numerous recent studies indicate that it is safe and has advantages in selected patients. Because of the magnified view offered by the laparoscope under pneumoperitoneal pressure, LH results in less bleeding than open laparotomy. However, gas embolism is an important concern that has been discussed in the literature, and experimental studies have shown that LH is associated with a high incidence of gas embolism. Major hepatectomies are done laparoscopically in some centers, even though the risk of gas embolism is believed to be higher than for minor hepatectomy due to the wide transection plane with dissection of major hepatic veins and long operative time. At many high-volume centers, LH is performed at a pneumoperitoneal pressure less than 12 mmHg, and reports indicate that the rate of clinically severe gas embolism is low. However, more studies will be necessary to elucidate the optimal pneumoperitoneal pressure and the incidence of gas embolism during LH.
Literature
1.
go back to reference Buell JF, Cherqui D, Geller DA, O’Rourke N, Iannitti D, Dagher I, et al. The international position on laparoscopic liver surgery. The Louisville statement, 2008. Ann Surg. 2009;250:825–30.PubMedCrossRef Buell JF, Cherqui D, Geller DA, O’Rourke N, Iannitti D, Dagher I, et al. The international position on laparoscopic liver surgery. The Louisville statement, 2008. Ann Surg. 2009;250:825–30.PubMedCrossRef
2.
go back to reference Huscher CGS, Lirici MM, Chiodini S. Laparoscopic liver resections. Semin Laparosc Surg. 1998;5:204–10.PubMed Huscher CGS, Lirici MM, Chiodini S. Laparoscopic liver resections. Semin Laparosc Surg. 1998;5:204–10.PubMed
3.
go back to reference Dagher I, Giuro GD, Dubrez J, Lainas P, Smadja C, Franco D. Laparoscopic versus open right hepatectomy: a comparative study. Am J Surg. 2009;198:173–7.PubMedCrossRef Dagher I, Giuro GD, Dubrez J, Lainas P, Smadja C, Franco D. Laparoscopic versus open right hepatectomy: a comparative study. Am J Surg. 2009;198:173–7.PubMedCrossRef
4.
go back to reference Vibert E, Perniceni T, Levard H, Denet C, Shahri NK, Gayet B. Laparoscopic liver resection. Br J Surg. 2006;93:67–72.PubMedCrossRef Vibert E, Perniceni T, Levard H, Denet C, Shahri NK, Gayet B. Laparoscopic liver resection. Br J Surg. 2006;93:67–72.PubMedCrossRef
5.
go back to reference O’Rourke N, Fielding G. Laparoscopic right hepatectomy: surgical technique. J Gastrointest Surg. 2004;8:213–6.PubMedCrossRef O’Rourke N, Fielding G. Laparoscopic right hepatectomy: surgical technique. J Gastrointest Surg. 2004;8:213–6.PubMedCrossRef
6.
go back to reference Gayat B, Cavaliere D, Vibert E, Perniceni T, Levard H, Denet C, et al. Totally laparoscopic right hepatectomy. Am J Surg. 2007;194:685–9.CrossRef Gayat B, Cavaliere D, Vibert E, Perniceni T, Levard H, Denet C, et al. Totally laparoscopic right hepatectomy. Am J Surg. 2007;194:685–9.CrossRef
7.
go back to reference Otsuka Y, Tsuchiya M, Maeda T, Katagiri T, Isii J, Tamura A, et al. Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepatobiliary Pancreat Surg. 2009;16:720–5.PubMedCrossRef Otsuka Y, Tsuchiya M, Maeda T, Katagiri T, Isii J, Tamura A, et al. Laparoscopic hepatectomy for liver tumors: proposals for standardization. J Hepatobiliary Pancreat Surg. 2009;16:720–5.PubMedCrossRef
8.
go back to reference Koffron AJ, Auffenberg G, Kung R, Abecassis M. Evaluation of 300 minimally invasive liver resections at a single institution: less is more. Ann Surg. 2007;246:385–92.PubMedCrossRef Koffron AJ, Auffenberg G, Kung R, Abecassis M. Evaluation of 300 minimally invasive liver resections at a single institution: less is more. Ann Surg. 2007;246:385–92.PubMedCrossRef
9.
go back to reference Kaneko H, Tsuchiya M, Otsuka Y, Yajima S, Minagawa T, Watanabe M, et al. Laparoscopic hepatectomy for hepatocellular carcinoma in cirrhotic patients. J Hepatobiliary Pancreat Surg. 2009;16:433–8.PubMedCrossRef Kaneko H, Tsuchiya M, Otsuka Y, Yajima S, Minagawa T, Watanabe M, et al. Laparoscopic hepatectomy for hepatocellular carcinoma in cirrhotic patients. J Hepatobiliary Pancreat Surg. 2009;16:433–8.PubMedCrossRef
10.
go back to reference Lantz PE, Smith JD. Fatal carbon dioxide embolism complicating attempted laparoscopic cholecystectomy: case report and literature review. J Forensic Sci. 1994;39:1468–80.PubMed Lantz PE, Smith JD. Fatal carbon dioxide embolism complicating attempted laparoscopic cholecystectomy: case report and literature review. J Forensic Sci. 1994;39:1468–80.PubMed
11.
go back to reference Landercasper J, Miller GJ, Strutt PJ, Olson RA, Boyd WC. Carbon dioxide embolization and laparoscopic cholecystectomy. Surg Laparosc Endosc. 1993;3:407–10.PubMed Landercasper J, Miller GJ, Strutt PJ, Olson RA, Boyd WC. Carbon dioxide embolization and laparoscopic cholecystectomy. Surg Laparosc Endosc. 1993;3:407–10.PubMed
12.
go back to reference Beck DH, McQuillan PJ. Fatal carbon dioxide embolism and severe haemorrhage during laparoscopic salpingectomy. Br J Anaesth. 1994;72:243–5.PubMedCrossRef Beck DH, McQuillan PJ. Fatal carbon dioxide embolism and severe haemorrhage during laparoscopic salpingectomy. Br J Anaesth. 1994;72:243–5.PubMedCrossRef
13.
go back to reference Hashizume M, Takenaka K, Yanaga K, Ohta M, Kajiyama K, Shirabe K, et al. Laparoscopic hepatic resection for hepatocellular carcinoma. Surg Endosc. 1995;9:1289–91.PubMedCrossRef Hashizume M, Takenaka K, Yanaga K, Ohta M, Kajiyama K, Shirabe K, et al. Laparoscopic hepatic resection for hepatocellular carcinoma. Surg Endosc. 1995;9:1289–91.PubMedCrossRef
14.
go back to reference Cottin V, Delafosse B, Viale JP. Gas embolism during laparoscopy: a report of seven cases in patients with previous abdominal surgical history. Surg Endosc. 1996;10:166–9.PubMedCrossRef Cottin V, Delafosse B, Viale JP. Gas embolism during laparoscopy: a report of seven cases in patients with previous abdominal surgical history. Surg Endosc. 1996;10:166–9.PubMedCrossRef
15.
go back to reference Sharma KC, Kabinoff G, Ducheine Y, Tierney J, Brandstetter RD. Laparoscopic surgery and its potential for medical complications. Heart Lung. 1997;26:52–64.PubMedCrossRef Sharma KC, Kabinoff G, Ducheine Y, Tierney J, Brandstetter RD. Laparoscopic surgery and its potential for medical complications. Heart Lung. 1997;26:52–64.PubMedCrossRef
16.
go back to reference Lindberg F, Bergqvist D, Rasmussen I. Incidence of thromboembolic complications after laparoscopic cholecystectomy: review of the literature. Surg Laparosc Endosc. 1997;7:324–31.PubMedCrossRef Lindberg F, Bergqvist D, Rasmussen I. Incidence of thromboembolic complications after laparoscopic cholecystectomy: review of the literature. Surg Laparosc Endosc. 1997;7:324–31.PubMedCrossRef
17.
18.
go back to reference Kaneko H, Takagi S, Shiba T. Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery. 1996;120:468–75.PubMedCrossRef Kaneko H, Takagi S, Shiba T. Laparoscopic partial hepatectomy and left lateral segmentectomy: technique and results of a clinical series. Surgery. 1996;120:468–75.PubMedCrossRef
19.
go back to reference Takagi S. Hepatic and portal vein blood flow during carbon dioxide pneumoperitoneum for laparoscopic hepatectomy. Surg Endosc. 1998;12:427–31.PubMedCrossRef Takagi S. Hepatic and portal vein blood flow during carbon dioxide pneumoperitoneum for laparoscopic hepatectomy. Surg Endosc. 1998;12:427–31.PubMedCrossRef
20.
go back to reference Lango T, Morland T, Brubakk AO. Diffusion coefficients and solubility coefficients for gases in biological fluids and tissues: a review. Undersea Hyperb Med. 1996;23:247–72.PubMed Lango T, Morland T, Brubakk AO. Diffusion coefficients and solubility coefficients for gases in biological fluids and tissues: a review. Undersea Hyperb Med. 1996;23:247–72.PubMed
22.
go back to reference Buell JF, Koffron AJ, Thomas MJ, Rudich S, Abecassis M, Woodle ES. Laparoscopic liver resection. J Am Coll Surg. 2005;200:472–80.PubMedCrossRef Buell JF, Koffron AJ, Thomas MJ, Rudich S, Abecassis M, Woodle ES. Laparoscopic liver resection. J Am Coll Surg. 2005;200:472–80.PubMedCrossRef
23.
go back to reference Jaskille A, Schechner A, Park K, Williams M, Wang D, Sava J. Abdominal insufflation decreases blood loss and mortality after porcine liver injury. J Trauma. 2005;59:1305–8.PubMedCrossRef Jaskille A, Schechner A, Park K, Williams M, Wang D, Sava J. Abdominal insufflation decreases blood loss and mortality after porcine liver injury. J Trauma. 2005;59:1305–8.PubMedCrossRef
24.
go back to reference Makuuchi M, Hasegawa H, Yamazaki S. Ultrasonically guided subsegmentectomy. Surg Gynecol Obstet. 1985;161:346–50.PubMed Makuuchi M, Hasegawa H, Yamazaki S. Ultrasonically guided subsegmentectomy. Surg Gynecol Obstet. 1985;161:346–50.PubMed
25.
go back to reference DeMatteo RP, Fong Y, Jarnagin WR, Blumgart LH. Recent advances in hepatic resection. Semin Surg Oncol. 2000;19:200–7.PubMedCrossRef DeMatteo RP, Fong Y, Jarnagin WR, Blumgart LH. Recent advances in hepatic resection. Semin Surg Oncol. 2000;19:200–7.PubMedCrossRef
26.
go back to reference Jones BR, Moulton CE, Hardy KJ. Central venous pressure and its effect on blood loss during liver resection. Br J Surg. 1998;85:1058–60.PubMedCrossRef Jones BR, Moulton CE, Hardy KJ. Central venous pressure and its effect on blood loss during liver resection. Br J Surg. 1998;85:1058–60.PubMedCrossRef
27.
go back to reference Hatano Y, Murakawa M, Segawa H, Nishida Y, Mori K. Venous air embolism during hepatic resection. Anesthesiology. 1990;73:1282–5.PubMedCrossRef Hatano Y, Murakawa M, Segawa H, Nishida Y, Mori K. Venous air embolism during hepatic resection. Anesthesiology. 1990;73:1282–5.PubMedCrossRef
28.
go back to reference Melendez J, Ferri E, Fischer ME, Wuest D, Jarnagin WR, Fong Y, et al. Perioperative outcomes of major hepatic resections under low central venous pressure anesthesia: blood loss, blood transfusion, and the risk of postoperative renal dysfunction. J Am Coll Surg. 1998;187:620–5.PubMedCrossRef Melendez J, Ferri E, Fischer ME, Wuest D, Jarnagin WR, Fong Y, et al. Perioperative outcomes of major hepatic resections under low central venous pressure anesthesia: blood loss, blood transfusion, and the risk of postoperative renal dysfunction. J Am Coll Surg. 1998;187:620–5.PubMedCrossRef
29.
go back to reference Schmandra TC, Mierdl S, Bauer H, Gutt C, Hanisch E. Transesophageal echocardiography shows high risk of gas embolism during laparoscopic hepatic resection under carbon dioxide pneumoperitoneum. Br J Surg. 2002;89:870–6.PubMedCrossRef Schmandra TC, Mierdl S, Bauer H, Gutt C, Hanisch E. Transesophageal echocardiography shows high risk of gas embolism during laparoscopic hepatic resection under carbon dioxide pneumoperitoneum. Br J Surg. 2002;89:870–6.PubMedCrossRef
30.
go back to reference Schmandra TC, Hollander D, Hanisch E, Gutt C. Risk of gas embolism in hand-assisted versus total laparoscopic hepatic resection. Surg Technol Int. 2004;12:137–43.PubMed Schmandra TC, Hollander D, Hanisch E, Gutt C. Risk of gas embolism in hand-assisted versus total laparoscopic hepatic resection. Surg Technol Int. 2004;12:137–43.PubMed
31.
go back to reference Eiriksson K, Fors D, Rubertsson S, Arvidsson D. High intra-abdominal pressure during experimental laparoscopic liver resection reduces bleeding but increases the risk of gas embolism. Br J Surg. 2011;98:845–52.PubMedCrossRef Eiriksson K, Fors D, Rubertsson S, Arvidsson D. High intra-abdominal pressure during experimental laparoscopic liver resection reduces bleeding but increases the risk of gas embolism. Br J Surg. 2011;98:845–52.PubMedCrossRef
32.
go back to reference Jayaraman S, Khakhar A, Yang H, Bainbridge D, Quan D. The association between central venous pressure, pneumoperitoneum, and venous carbon dioxide embolism in laparoscopic hepatectomy. Surg Endosc. 2009;23:2369–73.PubMedCrossRef Jayaraman S, Khakhar A, Yang H, Bainbridge D, Quan D. The association between central venous pressure, pneumoperitoneum, and venous carbon dioxide embolism in laparoscopic hepatectomy. Surg Endosc. 2009;23:2369–73.PubMedCrossRef
33.
go back to reference Dulucq JL, Wintringer P, Stabilini C, Berticelli J, Mahajna A. Laparoscopic liver resections: a single center experience. Surg Endosc. 2005;19:886–91.PubMedCrossRef Dulucq JL, Wintringer P, Stabilini C, Berticelli J, Mahajna A. Laparoscopic liver resections: a single center experience. Surg Endosc. 2005;19:886–91.PubMedCrossRef
34.
go back to reference Topal B, Fieuws S, Aerts R, Vandeweyer H, Penninckx F. Laparoscopic versus open liver resection of hepatic neoplasms: comparative analysis of short-term results. Surg Endosc. 2008;22:2208–13.PubMedCrossRef Topal B, Fieuws S, Aerts R, Vandeweyer H, Penninckx F. Laparoscopic versus open liver resection of hepatic neoplasms: comparative analysis of short-term results. Surg Endosc. 2008;22:2208–13.PubMedCrossRef
35.
go back to reference Cho JY, Han HS, Yoon YS, Shin SH. Experiences of laparoscopic liver resection including lesions in the posterosuperior segments of the liver. Surg Endosc. 2008;22:2344–9.PubMedCrossRef Cho JY, Han HS, Yoon YS, Shin SH. Experiences of laparoscopic liver resection including lesions in the posterosuperior segments of the liver. Surg Endosc. 2008;22:2344–9.PubMedCrossRef
36.
go back to reference Bryant R, Laurent A, Tayar C, Cherqui D. Laparoscopic liver resection—understanding its role in current practice: the Henri Mondor Hospital experience. Ann Surg. 2009;250:103–11.PubMedCrossRef Bryant R, Laurent A, Tayar C, Cherqui D. Laparoscopic liver resection—understanding its role in current practice: the Henri Mondor Hospital experience. Ann Surg. 2009;250:103–11.PubMedCrossRef
37.
go back to reference Cannon RM, Brock GN, Marvin MR, Buell JF. Laparoscopic liver resection: an examination of our first 300 patients. J Am Coll Surg. 2011;213:501–7.PubMedCrossRef Cannon RM, Brock GN, Marvin MR, Buell JF. Laparoscopic liver resection: an examination of our first 300 patients. J Am Coll Surg. 2011;213:501–7.PubMedCrossRef
38.
go back to reference Choi GH, Choi SH, Kim SH, Hwang HK, Kang CM, Choi JS, et al. Robotic liver resection: technique and results of 30 consecutive procedures. Surg Endosc. 2012; 26:2247–2258 Choi GH, Choi SH, Kim SH, Hwang HK, Kang CM, Choi JS, et al. Robotic liver resection: technique and results of 30 consecutive procedures. Surg Endosc. 2012; 26:2247–2258
39.
go back to reference Abu Hilal M, Di Fabio F, Abu Salameh M, Pearce NW, et al. Oncological efficiency analysis of laparoscopic liver resection for primary and metastatic cancer: a single-center UK experience. Arch Surg. 2012;147:42–8.PubMedCrossRef Abu Hilal M, Di Fabio F, Abu Salameh M, Pearce NW, et al. Oncological efficiency analysis of laparoscopic liver resection for primary and metastatic cancer: a single-center UK experience. Arch Surg. 2012;147:42–8.PubMedCrossRef
40.
go back to reference Dagher I, O’Rourke N, Geller DA. Laparoscopic major hepatectomy. An evolution in standard of care. Ann Surg. 2009;250:856–60.PubMedCrossRef Dagher I, O’Rourke N, Geller DA. Laparoscopic major hepatectomy. An evolution in standard of care. Ann Surg. 2009;250:856–60.PubMedCrossRef
41.
go back to reference Cugat E, Pérez-Romero N, Rotellar F, Suárez MA, Gastaca M, Artigas V, et al. Laparoscopic liver surgery: 8 years of multicenter Spanish register. J Hepatobiliary Pancreat Sci. 2010;17:262–8.PubMedCrossRef Cugat E, Pérez-Romero N, Rotellar F, Suárez MA, Gastaca M, Artigas V, et al. Laparoscopic liver surgery: 8 years of multicenter Spanish register. J Hepatobiliary Pancreat Sci. 2010;17:262–8.PubMedCrossRef
Metadata
Title
Gas embolism in laparoscopic hepatectomy: what is the optimal pneumoperitoneal pressure for laparoscopic major hepatectomy?
Authors
Yuichiro Otsuka
Toshio Katagiri
Jun Ishii
Tetsuya Maeda
Yoshihisa Kubota
Akira Tamura
Masaru Tsuchiya
Hironori Kaneko
Publication date
01-02-2013
Publisher
Springer Japan
Published in
Journal of Hepato-Biliary-Pancreatic Sciences / Issue 2/2013
Print ISSN: 1868-6974
Electronic ISSN: 1868-6982
DOI
https://doi.org/10.1007/s00534-012-0556-0

Other articles of this Issue 2/2013

Journal of Hepato-Biliary-Pancreatic Sciences 2/2013 Go to the issue