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Published in:

01-10-2016 | Original Article

Sleep disorders in breast cancer survivors

Authors: Julie L. Otte, Lorie Davis, Janet S. Carpenter, Connie Krier, Todd C. Skaar, Kevin L. Rand, Michael Weaver, Carol Landis, Yelena Chernyak, Shalini Manchanda

Published in: Supportive Care in Cancer | Issue 10/2016

Abstract

Purpose

The purpose of this study was to evaluate the feasibility, acceptability, and initial results of a structured assessment of sleep disorders in breast cancer survivors (BCS). Our goal was to determine whether the assessment could be easily used and whether it would capture problems suggestive of one or more underlying sleep disorders that require referral to a specialist for diagnostic validation through polysomnography and appropriate specialty treatment.

Methods

A cross-sectional, feasibility study using convenience sampling.

Results

A total of 38 BCS completed the study. Recruitment procedures were adequate in finding eligible BCS, however, procedures used to establish possible patterns of sleep disorders (e.g., interview) were not feasible for screening for sleep disorders in the clinical setting due to the time it took to complete each interview. A total of seven sleep disorder categories were identified in the data with the majority of women having at least one possible sleep disorder.

Conclusions

Study findings suggest that population-based screening for sleep disorders in clinical practice should be a priority for BCS reporting chronic sleep problems.

Centers for Disease Control and Prevention (2014) Sleep and sleep disorders. Centers for Disease Control and Prevention. http://www.cdc.gov/sleep/index.html. Accessed June 1 2015

Beck SL, Schwartz AL, Towsley G, Dudley W, Barsevick A (2004) Psychometric evaluation of the Pittsburgh Sleep Quality Index in cancer patients. J Pain Symptom Manag 27(2):140–148CrossRef

Berger AM, Higginbotham P (2000) Correlates of fatigue during and following adjuvant breast cancer chemotherapy: a pilot study. Oncol Nurs Forum 27(9):1443–1148PubMed

Bower JE, Ganz PA, Desmond KA, Rowland JH, Meyerowitz BE, Belin TR (2000) Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. J Clin Oncol 18(4):743–753PubMed

Carpenter JS, Elam J, Ridner S, Carney P, Cherry G, Cucullu H (2004) Sleep, fatigue, and depressive symptoms in breast cancer survivors and matched healthy women experiencing hot flashes. Oncol Nurs Forum 31(3):591–5598CrossRefPubMed

Davidson JR, MacLean AW, Brundage MD, Schulze K (2002) Sleep disturbance in cancer patients. Soc Sci Med 54(9):1309–1321CrossRefPubMed

Engstrom CA, Strohl RA, Rose L, Lewandowski L, Stefanek ME (1999) Sleep alterations in cancer patients. Cancer Nurs 22(2):143–148CrossRefPubMed

Fortner BV, Stepanski EJ, Wang SC, Kasprowicz S, Durrence HH (2002) Sleep and quality of life in breast cancer patients. J Pain Symptom Manag 24(5):471–480CrossRef

Koopman C, Nouriani B, Erickson V, Anupindi R, Butler LD, Bachmann MH, Sephton SE, Spiegel D (2002) Sleep disturbances in women with metastatic breast cancer. Breast J 8(6):362–370CrossRefPubMed

10.

Lee K, Cho M, Miaskowski C, Dodd M (2004) Impaired sleep and rhythms in persons with cancer. Sleep Med Rev 8(3):199–212CrossRefPubMed

11.

Roscoe JA, Morrow GR, Hickok JT, Bushunow P, Matteson S, Rakita D, Andrews PL (2002) Temporal interrelationships among fatigue, circadian rhythm and depression in breast cancer patients undergoing chemotherapy treatment. Support Care Cancer 10(4):329–336CrossRefPubMed

12.

Savard J, Morin CM (2001) Insomnia in the context of cancer: a review of a neglected problem. J Clin Oncol 19(3):895–908PubMed

13.

Deimling GT, Kahana B, Bowman KF, Schaefer ML (2002) Cancer survivorship and psychological distress in later life. Psychooncology 11(6):479–494CrossRefPubMed

14.

Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR (2002) Quality of life in long-term, disease-free survivors of breast cancer: a follow-up study. J Natl Cancer Inst 94(1):39–49CrossRefPubMed

15.

Otte JL, Carpenter JS, Russell KM, Bigatti S, Champion VL (2010) Prevalence, severity, and correlates of sleep-wake disturbances in long-term breast cancer survivors. J Pain Symptom Manag 39(3):535–547CrossRef

16.

Savard J, Simard S, Blanchet J, Ivers H, Morin CM (2001) Prevalence, clinical characteristics, and risk factors for insomnia in the context of breast cancer. Sleep 24(5):583–590PubMed

17.

National Center for Chronic Disease Prevention and Health Promotion (2004) Cancer survivorship—United States, 1971–2001 morbidity and mortaility weekly report, vol 53. CDC National Center for Chronic Disease Prevention and Health Promotion, Atlanta

18.

Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61(2):69–90. doi:10.3322/caac.20107 CrossRefPubMed

19.

Berger AM, Parker KP, Young-McCaughan S, Mallory GA, Barsevick AM, Beck SL, Carpenter JS, Carter PA, Farr LA, Hinds PS, Lee KA, Miaskowski C, Mock V, Payne JK, Hall M (2005) Sleep wake disturbances in people with cancer and their caregivers: state of the science. Oncol Nurs Forum 32(6):E98–E126CrossRefPubMed

20.

Vena C, Parker K, Allen R, Bliwise D, Jain S, Kimble L (2006) Sleep-wake disturbances and quality of life in patients with advanced lung cancer. Oncol Nurs Forum 33(4):761–769CrossRefPubMed

21.

Otte JL, Carpenter JS, Manchanda S, Rand KL, Skaar TC, Weaver M, Chernyak Y, Zhong X, Igega C, Landis C (2015) Systematic review of sleep disorders in cancer patients: can the prevalence of sleep disorders be ascertained? Cancer Med 4(2):183–200. doi:10.1002/cam4.356 CrossRefPubMed

22.

Richardon G Update on the science, diagnosis and managment of insomnia. In: Richardson G (ed) International Congress and Symposium Series., London, 2005. Royal Society of Medicine Press, pp iii-76

23.

Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ (1989) The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Res 28(2):193–213CrossRefPubMed

24.

Tiffin P, Ashton H, Marsh R, Kamali F (1995) Pharmacokinetic and pharmacodynamic responses to caffeine in poor and normal sleepers. Psychopharmacology (Berlin) 121(4):494–502CrossRef

25.

Pasternak RE, Reynolds CF 3rd, Houck PR, Schlernitzauer M, Buysse DJ, Hoch CC, Kupfer DJ (1994) Sleep in bereavement-related depression during and after pharmacotherapy with nortriptyline. J Geriatr Psychiatry Neurol 7(2):69–73CrossRefPubMed

26.

Gentili A, Weiner DK, Kuchibhatla M, Edinger JD (1995) Test–retest reliability of the Pittsburgh Sleep Quality Index in nursing home residents. J Am Geriatr Soc 43(11):1317–1318CrossRefPubMed

27.

Carpenter JS, Andrykowski MA (1998) Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 45(1):5–13CrossRefPubMed

28.

Kroenke K, Spitzer RL, Williams JB (2001) The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med 16(9):606–613CrossRefPubMedPubMedCentral

29.

Monahan PO, Shacham E, Reece M, Kroenke K, Ong’or WO, Omollo O, Yebei VN, Ojwang C (2009) Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western Kenya. J Gen Intern Med 24(2):189–197. doi:10.1007/s11606-008-0846-z CrossRefPubMed

30.

Sangha O, Stucki G, Liang MH, Fossel AH, Katz JN (2003) The self-administered comorbidity questionnaire: a new method to assess comorbidity for clinical and health services research. Arthritis Rheum 49(2):156–163CrossRefPubMed

31.

Spitzer RL, Kroenke K, Williams JB, Lowe B (2006) A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 166(10):1092–1097. doi:10.1001/archinte.166.10.1092 CrossRefPubMed

32.

Kroenke K, Spitzer RL, Williams JB, Monahan PO, Lowe B (2007) Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection. Ann Intern Med 146(5):317–325CrossRefPubMed

33.

Carpenter JS (2001) The hot flash related daily interference scale: a tool for assessing the impact of hot flashes on quality of life following breast cancer. J Pain Symptom Manag 22(6):979–989CrossRef

34.

Carpenter JS, Storniolo AM, Johns S, Monahan PO, Azzouz F, Elam JL, Johnson CS, Shelton RC (2007) Randomized, double-blind, placebo-controlled crossover trials of venlafaxine for hot flashes after breast cancer. Oncologist 12(1):124–135CrossRefPubMed

35.

Krebs EE, Lorenz KA, Bair MJ, Damush TM, Wu J, Sutherland JM, Asch SM, Kroenke K (2009) Development and initial validation of the PEG, a three-item scale assessing pain intensity and interference. J Gen Intern Med 24(6):733–738. doi:10.1007/s11606-009-0981-1 CrossRefPubMedPubMedCentral

36.

Edinger JD, Wyatt JK, Stepanski EJ, Olsen MK, Stechuchak KM, Carney CE, Chiang A, Crisostomo MI, Lineberger MD, Means MK, Radtke RA, Wohlgemuth WK, Krystal AD (2011) Testing the reliability and validity of DSM-IV-TR and ICSD-2 insomnia diagnoses. Results of a multitrait-multimethod analysis. Arch Gen Psychiatry 68(10):992–1002. doi:10.1001/archgenpsychiatry.2011.64 CrossRefPubMed

37.

Rumble ME, Keefe FJ, Edinger JD, Affleck G, Marcom PK, Shaw HS (2010) Contribution of cancer symptoms, dysfunctional sleep related thoughts, and sleep inhibitory behaviors to the insomnia process in breast cancer survivors: a daily process analysis. Sleep 33(11):1501–1509PubMedPubMedCentral

38.

Carpenter JS, Neal JG, Payne JK, Kimmick G, Storniolo AM (2007) Cognitive-behavioral intervention for hot flashes. Oncol Nurs Forum 34(1):E1–E8CrossRef

39.

American Academy of Sleep Medicine (2005) The International Classification of Sleep Disorders: Diagnostic and Coding Manual, 2nd edn. American Academy of Sleep Medicine, Westchester

40.

Billingham SA, Whitehead AL, Julious SA (2013) An audit of sample sizes for pilot and feasibility trials being undertaken in the United Kingdom registered in the United Kingdom clinical research network database. BMC Med Res Methodol 13:104. doi:10.1186/1471-2288-13-104 CrossRefPubMedPubMedCentral

41.

Moore CG, Carter RE, Nietert PJ, Stewart PW (2011) Recommendations for planning pilot studies in clinical and translational research. Clin Transl Sci 4(5):332–337. doi:10.1111/j.1752-8062.2011.00347.x CrossRefPubMedPubMedCentral

42.

Reinsel RA, Starr TD, O’Sullivan B, Passik SD, Kavey NB (2015) Polysomnographic study of sleep in survivors of breast cancer. J Clin Sleep Med 11(12):1361–1370. doi:10.5664/jcsm.5264 CrossRefPubMedPubMedCentral

43.

Freedman RR, Roehrs TA (2005) Lack of sleep disturbance from menopausal hot flashes. Obstet Gynecol Surv 60(2):106–107CrossRef

44.

Shaver JL, Woods NF (2015) Sleep and menopause: a narrative review. Menopause 22(8):899–915. doi:10.1097/GME.0000000000000499 CrossRefPubMed

45.

Attarian HP, Viola-Saltzman M (2006) Sleep disorders in women: a guide to practical management, 2 ednth edn. Humana Press, Totowa, Current clinical neurologyCrossRef

Title: Sleep disorders in breast cancer survivors
Authors: Julie L. Otte
Lorie Davis
Janet S. Carpenter
Connie Krier
Todd C. Skaar
Kevin L. Rand
Michael Weaver
Carol Landis
Yelena Chernyak
Shalini Manchanda
Publication date: 01-10-2016
Publisher: Springer Berlin Heidelberg
Published in: Supportive Care in Cancer / Issue 10/2016
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI: https://doi.org/10.1007/s00520-016-3247-6

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Abstract

Purpose

Methods

Results

Conclusions

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