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01-04-2013 | Review

Nutritional management and growth in children with chronic kidney disease

Authors: Lesley Rees, Helen Jones

Published in: Pediatric Nephrology | Issue 4/2013

Abstract

Despite continuing improvements in our understanding of the causes of poor growth in chronic kidney disease, many unanswered questions remain: why do some patients maintain a good appetite whereas others have profound anorexia at a similar level of renal function? Why do some, but not all, patients respond to increased nutritional intake? Is feed delivery by gastrostomy superior to oral and nasogastric routes? Do children who are no longer in the ‘infancy’ stage of growth benefit from enteral feeding? Do patients with protein energy wasting benefit from increased nutritional input? How do we prevent obesity, which is becoming so prevalent in the developed world? This review will address these issues.

Betts PR, Magrath G (1974) Growth pattern and dietary intake of children with chronic renal insufficiency. Br Med J 2:189–193PubMedCrossRef

Seikaly MG, Salhab N, Gipson D, Yiu V, Stablein D (2006) Stature in children with chronic kidney disease; analysis of NAPRTCS database. Pediatr Nephrol 12:793–799CrossRef

Strife CF, Quinlan M, Mears K, Davey ML, Clardy C (1986) Improved growth of three uremic children by nocturnal nasogastric feedings. Am J Dis Child 140:438–443PubMed

Guillot M, Broyer M, Cathelineau L, Boulegue D, Dartois AM, Folio D, Guimbaud P (1980) Continuous enteral feeding in pediatric nephrology. Long-term results in children with congenital nephrotic syndrome, severe cystinosis and renal failure. Arch Fr Pediatr 37:497–505PubMed

Rees L, Rigden SPA, Ward GM (1989) Chronic renal failure and growth. Arch Dis Child 64:573–577PubMedCrossRef

Rees L, Brandt M (2010) Nutritional support in children with CKD: technical and practical issues. Pediatr Nephrol 25:699–704PubMedCrossRef

Hijazi R, Abitbol CL, Chandar J, Seeherunvong W, Freundlich M, Zilleruelo G (2009) Twenty-five years of infant dialysis: a single center experience. J Pediatr 155:111–117PubMedCrossRef

Mekhali D, Shaw V, Ledermann SE, Rees L (2010) Long term outcome of infants with severe CKD. Clin J Am Soc Nephrol 5:10–17CrossRef

Shroff R, Rees L, Trompeter RS, Hutchinson C, Ledermann S (2005) Long-term outcome of chronic dialysis in children. Pediatr Nephrol 21:257–266PubMedCrossRef

10.

Greenbaum LA, Muñoz A, Schneider MF, Kaskel FJ, Ashkenazi DJ, Jenkins R, Hitchkiss H, Moxey-Mims M, Furth SL, Warady BA (2011) The association between abnormal birth history and growth in children with CKD. Clin J Am Soc Nephrol 6:14–21PubMedCrossRef

11.

North American Pediatric Renal Trials and Collaborative Studies (2005) NAPRTCS annual report 2005. Available at: https://web.emmes.com/study/ped/annlrept/annlrept2005.pdf

12.

United States Renal Data System (USRDS) (2008) Report. USRDS Coordinating Center, Minneapolis, pp 296–297

13.

International Pediatric PD Network. Available at: http://www.pedpd.org/index.php?id=98

14.

Rees L, Mak RH (2011) Nutrition and growth in children with chronic kidney disease. Nat Rev Nephrol 7:615–623PubMedCrossRef

15.

Lewis M, Joanne Shaw J, Reid C, Evans J, Webb N, Verrier-Jones K (2007) Growth in children with established renal failure—a Registry analysis (Chapter 14). Nephrol Dial Transplant 22[Suppl 7]:vii176–vii180PubMedCrossRef

16.

North American Pediatric Renal Trials and Collaborative Studies (2006) NAPRTCS annual report: renal transplantation, dialysis, chronic renal insufficiency. NAPRTCS, Boston

17.

North American Pediatric Renal Trials and Collaborative Studies (2011) NAPRTCS annual dialysis report. Available at: https://web.emmes.com/study/ped/annlrept/annualrept2011.pdf

18.

Gorman G, Frankenfield D, Fivush B, Neu A (2008) Linear growth in pediatric hemodialysis patients. Pediatr Nephrol 23:123–127PubMedCrossRef

19.

Hussain F, Castledine C, van Schalkwyk D, Manish D, Sinha MD, Lewis M, Inward C (2010) UK Renal Registry 12th Annual Report (December 2009): Chapter 15 Clinical, Haematological and Biochemical Parameters in Patients receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2008: national and centre-specific analyses. Nephron Clin Pract 115[Suppl1]:c289–c308PubMedCrossRef

20.

Fine RN, Martz K, Stablein D (2010) What have 20 years of data from the North American Pediatric Renal Transplant Cooperative Study taught us about growth following renal transplantation in infants, children, and adolescents with end-stage renal disease? Pediatr Nephrol 25:739–746PubMedCrossRef

21.

Bérard E, André JL, Guest G, Berthier F, Afanetti M, Cochat P, Broyer M, French Society for Pediatric Nephrology (2008) Long-term results of rhGH treatment in children with renal failure: experience of the French Society of Pediatric Nephrology. Pediatr Nephrol 23:2031–2038PubMedCrossRef

22.

André JL, Bourquard R, Guillemin F, Krier MJ, Briançon S (2003) Final height in children with chronic renal failure who have not received growth hormone. Pediatr Nephrol 18:685–691PubMed

23.

Rosenkranz J, Reichwald-Klugger E, Oh J, Turzer M, Mehls O, Schaefer F (2005) Psychosocial rehabilitation and satisfaction with life in adults with childhood-onset of end-stage renal disease. Pediatr Nephrol 20:1288–1294PubMedCrossRef

24.

Armstrong JE, Laing DG, Wilkes FJ, Kainer G (2010) Smell and taste function in children with chronic kidney disease. Pediatr Nephrol 25:1497–1504PubMedCrossRef

25.

Büscher AK, Büscher R, Hauffa BP, Hoyer PF (2010) Alterations in appetite-regulating hormones influence protein-energy wasting in pediatric patients with chronic kidney disease. Pediatr Nephrol 25:1497–1504CrossRef

26.

Mak RH, Cheung W, Cone RD, Marks DL (2006) Leptin and inflammation-associated cachexia in chronic kidney disease. Kidney Int 69:794–797PubMedCrossRef

27.

Rees L, Shaw V (2007) Nutrition in children with CRF and on dialysis. Pediatr Nephrol 22:1689–1702PubMedCrossRef

28.

Rees L, Azocar M, Borzych D, Watson AR, Büscher A, Edefonti A, Bilge I, Askenazi D, Leozappa G, Gonzales C, van Hoeck K, Secker D, Zurowska A, Rönnholm K, Bouts AH, Stewart H, Ariceta G, Ranchin B, Warady BA, Schaefer F, for the International Pediatric Peritoneal Dialysis Network (IPPN) registry (2011) Growth in very young children undergoing chronic peritoneal dialysis. J Am Soc Nephrol 22:2303–2312PubMedCrossRef

29.

Laakkonen H, Happonen J-H, Marttinen E, Paganus A, Tuula Hölttä T, Holmberg C, Rönnholm K (2010) Normal growth and intravascular volume status with good metabolic control during peritoneal dialysis in infancy. Pediatr Nephrol 25:1529–1538PubMedCrossRef

30.

Karlberg J, Schaefer F, Hennicke M, Wingen AM, Rigden S, Mehls O (1996) Early age-dependent growth impairment in chronic renal failure. European Study Group for Nutritional Treatment of Chronic Renal Failure in Childhood. Pediatr Nephrol 10:283–287PubMed

31.

Shroff R, Rees L, Trompeter R, Hutchinson C, Ledermann S (2006) Long-term outcome of chronic dialysis in children. Pediatr Nephrol 21:257–264PubMedCrossRef

32.

Vidal E, Edefonti A, Murer L, Gianoglio B, Maringhini S, Pecoraro C, Sorino P, Leozappa G, Lavoratti G, Ratsch IM, Chimenz R, Verrina E, Italian Registry of Paediatric Chronic Dialysis (2012) Peritoneal dialysis in infants: the experience of the Italian Registry of Paediatric Chronic Dialysis. Nephrol Dial Transplant 27:388–395PubMedCrossRef

33.

Guzzo I, Mancini E, Wafo SK, Ravà L, Picca S (2009) Residual renal function and nutrition in young patients on chronic hemodialysis. Pediatr Nephrol 24:1391–1397PubMedCrossRef

34.

Jander A, Nowicki M, Tkaczyk M, Roszkowska-Blaim M, Jarmoliński T, Marczak E, Pałuba E, Pietrzyk JA, Siteń G, Stankiewicz R, Szprynger K, Zajaczkowska M, Zachwieja J, Zoch-Zwierz W, Zwolińska D (2006) Does a late referral to a nephrologist constitute a problem in children starting renal replacement therapy in Poland?—a nationwide study. Nephrol Dial Transplant 21:957–961PubMedCrossRef

35.

Parekh RS, Flynn JT, Smoyer WE, Milne JL, Kershaw DB, Bunchman TE, Sedman AB (2001) Improved growth in young children with severe chronic renal insufficiency who use specified nutritional therapy. J Am Soc Nephrol 12:2418–2426PubMed

36.

Kraut JA, Madias NE (2011) Consequences and therapy of the metabolic acidosis of chronic kidney disease. Pediatr Nephrol 26:19–28PubMedCrossRef

37.

Chan RSM, Woo J, Chan DCC, Cheung CSK, Lo DHS (2009) Estimated net endogenous acid production and intake of bone-health related nutrients in Hong Kong Chinese adolescents. Eur J Clin Nutr 63:505–512PubMedCrossRef

38.

Boehm M (2007) Early erythropoietin therapy is associated with improved growth in children with chronic kidney disease. Pediatr Nephrol 22:1189–1193PubMedCrossRef

39.

Borzych D, Rees L, Ha IS, Chua A, Valles PG, Lipka M, Zambrano P, Ahlenstiel T, Bakkaloglu SA, Spizzirri AP, Lopez L, Ozaltin F, Printza N, Hari P, Klaus G, Bak M, Vogel A, Ariceta G, Yap HK, Warady BA, Schaefer F, International Pediatric PD Network (IPPN) (2010) The bone and mineral disorder of children undergoing chronic peritoneal dialysis. Kidney Int 78:1295–1304PubMedCrossRef

40.

Cansick J, Waller S, Ridout D, Rees L (2007) Growth and PTH in prepubertal children on long-term dialysis. Pediatr Nephrol 22:1349–1354PubMedCrossRef

41.

Hölttä T, Rönnholm K, Jalanko H, Holmberg C (2000) Clinical outcome of pediatric patients on peritoneal dialysis under adequacy control. Pediatr Nephrol 14:889–897PubMedCrossRef

42.

Laakkonen H, Happonen JM, Marttinen E, Paganus A, Hölttä T, Holmberg C, Rönnholm K (2010) Normal growth and intravascular volume status with good metabolic control during peritoneal dialysis in infancy. Pediatr Nephrol 25:1529–1538PubMedCrossRef

43.

Brem AS, Lambert C, Hill C, Kitsen J, Shemin DG (2000) Outcome data on pediatric dialysis patients from the end-stage renal disease clinical indicators project. Am J Kidney Dis 36:310–317PubMedCrossRef

44.

van Hoeck KJ, Rusthoven E, Vermeylen L, Vandesompel A, Marescau B, Lilien M, Schroder CH (2003) Nutritional effects of increasing dialysis dose by adding an icodextrin daytime dwell to nocturnal intermittent peritoneal dialysis (NIPD) in children. Nephrol Dial Transplant 18:1383–1387PubMedCrossRef

45.

Fischbach M, Terzic J, Menouer S, Dheu C, Seuge L, Zalosczicet A (2010) Daily on line haemodiafiltration promotes catch-up growth in children on chronic dialysis. Nephrol Dial Transplant 25:867–873PubMedCrossRef

46.

Müller D, Zimmering M, Chan CT, McFarlane PA, Pierratos A, Querfeld U (2008) Intensified hemodialysis regimens: neglected treatment options for children and adolescents. Pediatr Nephrol 23:1729–1736PubMedCrossRef

47.

Hoppe A, von Puttkamer C, Linke U, Kahler C, Booß M, Braunauer-Kolberg R, Hofmann K, Joachimsky P, Hirte I, Schley S, Utsch B, Thumfart J, Briese S, Gellermann J, Zimmering M, Querfeld U, Müller D (2011) A hospital-based intermittent nocturnal hemodialysis program for children and adolescents. J Pediatr 158:95–99PubMedCrossRef

48.

Coleman JE, Norman LJ, Watson AR (1999) Provision of dietetic care in children on chronic peritoneal dialysis. J Ren Nutr 9:145–148PubMedCrossRef

49.

National Kidney Foundation Disease Outcomes Quality Initiative (2009) KDOQI clinical practice guideline for nutrition in children with CKD: 2008 update. Executive summary. Am J Kidney Dis 53:S11–S104

50.

Foster BJ, McCauley L, Mak RH (2011) Nutrition in infants and very young children with chronic kidney disease. Pediatr Nephrol. doi:10.1007/s00467-011-1983-x

51.

Ledermann SE, Shaw V, Trompeter RS (1999) Long-term enteral nutrition in infants and young children with chronic renal failure. Pediatr Nephrol 13:870–875PubMedCrossRef

52.

Norman LJ, Macdonald IA, Watson AR (2004) Optimising nutrition in chronic renal insufficiency—progression of disease. Pediatr Nephrol 19:1253–1261PubMedCrossRef

53.

Ramage IJ, Geary DF, Harvey E, Secker DJ, Balfe JA, Balfe JW (1999) Efficacy of gastrostomy feeding in infants and older children receiving chronic peritoneal dialysis. Perit Dial Int 19:231–236PubMed

54.

Wong CS, Hingorani S, Gillen DL, Sherrard DJ, Watkins SL, Brandt JR, Balll A, Stehman-Breen CO (2002) Hypoalbuminemia and risk of death in pediatric patients with end-stage renal disease. Kidney Int 61:630–637PubMedCrossRef

55.

Amaral S, Hwang W, Fivush B, Neu A, Frankenfield D, Furth S (2008) Serum albumin level and risk for mortality and hospitalization in adolescents on hemodialysis. Clin J Am Soc Nephrol 3:759–767PubMedCrossRef

56.

Mak RH, Cheung WW, Zhan J-Y, Shen Q, Foster BJ (2012) Cachexia and protein-energy wasting in children with chronic kidney disease. Pediatr Nephrol 27:173–181PubMedCrossRef

57.

Kalantar-Zadeh K, Cano NJ, Budde K, Chazot C, Kovesdy CP, Mak RH, Mehrotra R, Raj DS, Sehgal AR, Stenvinkel P, Ikizler TA (2011) Diets and enteral supplements for improving outcomes in chronic kidney disease. Nat Rev Nephrol 7:369–384PubMedCrossRef

58.

Hanevold CD, Ho PL, Talley L, Mitsnefes MM (2005) Obesity and renal transplant outcome: a report of the North American Pediatric renal transplant cooperative study. Pediatrics 115:352–356PubMedCrossRef

59.

Filler G, Payne R, Orrbine E, Clifford T, Drukker A, McLaine P (2005) Changing trends in the referral patterns of pediatric nephrology patients. Pediatr Nephrol 20:603–608PubMedCrossRef

60.

Sienna JL, Saqan R, Teh JC, Frieling ML, Secker D, Cornelius V, Geary DF (2010) Body size in children with chronic kidney disease after gastrostomy tube feeding. Pediatr Nephrol 25:2115–2121PubMedCrossRef

61.

Foster BJ, Martz K, Gowrishankar M, Stablein D, Al-Uzri A (2010) Weight and height changes and factors associated with greater weight and height gains after pediatric renal transplantation: a NAPRTCS study. Transplantation 89:1103–1112PubMedCrossRef

62.

Ellis D (2000) Growth and renal function after steroid-free tacrolimus-based immunosuppression in children with renal transplants. Pediatr Nephrol 14:689–694PubMedCrossRef

Title: Nutritional management and growth in children with chronic kidney disease
Authors: Lesley Rees
Helen Jones
Publication date: 01-04-2013
Publisher: Springer-Verlag
Published in: Pediatric Nephrology / Issue 4/2013
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-012-2258-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Nutritional management and growth in children with chronic kidney disease

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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