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01-05-2021 | Rectal Cancer

Impact of pelvic dimensions on anastomotic leak after anterior resection for patients with rectal cancer

Authors: Zhao-liang Yu, Xuan-hui Liu, Hua-shan Liu, Jia Ke, Yi-feng Zou, Wu-teng Cao, Jian Xiao, Zhi-yang Zhou, Ping Lan, Xiao-jian Wu, Xian-rui Wu

Published in: Surgical Endoscopy | Issue 5/2021

Abstract

Aim

The impact of pelvis on the development of anastomotic leak (AL) in rectal cancer (RC) patients who underwent anterior resection (AR) remains unclear. The aim of this study was to evaluate the impact of pelvic dimensions on the risk of AL.

Methods

A total of 1058 RC patients undergoing AR from January 2013 to January 2016 were enrolled. Pelvimetric parameters were obtained using abdominopelvic computed tomography scans.

Results

Univariate analyses showed that pelvic inlet, pelvic outlet, interspinous distance, and intertuberous distance were significantly associated with the risk for AL (P < 0.05). Multivariate analysis confirmed that pelvic inlet and intertuberous distance were independent risk factors for AL (P < 0.05). Significant factors from multivariate analysis were assembled into the nomogram A (without pelvic dimensions) and nomogram B (with pelvic dimensions). The area under curve (AUC) of nomogram B was 0.72 (95% CI 0.67–0.77), which was better than the AUC of nomogram A (0.69, [95% CI 0.65–0.74]), but didn’t reach a statistical significance (P = 0.199). Decision curve supported that nomogram B was better than nomogram A.

Conclusion

Pelvic dimensions, specifically pelvic inlet and intertuberous distance, seemed to be independent predictors for postoperative AL in RC patients. Pelvic inlet and intertuberous distance incorporated with preoperative radiotherapy, preoperative albumin, conversion, and tumor diameter in the nomogram might provide a clinical tool for predicting AL.

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Title: Impact of pelvic dimensions on anastomotic leak after anterior resection for patients with rectal cancer
Authors: Zhao-liang Yu
Xuan-hui Liu
Hua-shan Liu
Jia Ke
Yi-feng Zou
Wu-teng Cao
Jian Xiao
Zhi-yang Zhou
Ping Lan
Xiao-jian Wu
Xian-rui Wu
Publication date: 01-05-2021
Publisher: Springer US
Keywords: Rectal Cancer
Rectal Cancer
Radiotherapy
Published in: Surgical Endoscopy / Issue 5/2021
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-020-07617-1

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Impact of pelvic dimensions on anastomotic leak after anterior resection for patients with rectal cancer

Abstract

Aim

Methods

Results

Conclusion

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Aim

Methods

Results

Conclusion

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