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Published in: Surgical Endoscopy 11/2015

01-11-2015

A prospective non-randomised single-center study comparing laparoscopic and robotic distal pancreatectomy

Authors: Giovanni Butturini, Isacco Damoli, Lorenzo Crepaz, Giuseppe Malleo, Giovanni Marchegiani, Despoina Daskalaki, Alessandro Esposito, Sara Cingarlini, Roberto Salvia, Claudio Bassi

Published in: Surgical Endoscopy | Issue 11/2015

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Abstract

Background

Laparoscopic distal pancreatectomy (LDP) is increasing in popularity thanks to the benefits that have been recently demonstrated by many authors. The Da Vinci® Surgical System could overcome some limits of laparoscopy, helping the surgeons to perform safer and faster difficult procedures. Nowadays, prospective clinical trials comparing LDP to robotic distal pancreatectomy (RDP) are lacking. The aim of this study is to present a prospective comparison between the two techniques.

Methods

Since November 2011, all patients suitable for minimally invasive distal pancreatectomy were assigned either to LDP or RDP, depending on the availability of the Da Vinci® Surgical System for our Surgical Unit. Demographics, clinical, and intra- and postoperative data, including estimated costs of the procedure, were prospectively collected. Follow-up included cross-sectional imaging ended on April 2014.

Results

Twenty-two patients underwent RDP and 21 LDP; patients’ characteristics were similar. The median operative time was longer and procedures’ cost was double in RDP group. The conversion to open rate and the median length of postoperative hospital stay were 4.5 % and 7 days, respectively, in both groups. Pancreatic fistula developed in 57.1 % (12/21) and 50 % (11/22) of LDP and RDP, respectively (p = 0.870), being grade A the most frequent. Mortality was nil and an R0 resection was achieved in all Patients. The overall number of lymph nodes harvested was similar between the two groups.

Conclusions

Both RDP and LDP are valid techniques for the treatment of distal pancreatic tumors. The advantages of RDP are claimed by many but still under investigation. Some of these advantages are more subjective than objective, and it seems difficult to demonstrate a real superiority of one technique over the other in a standardized fashion. In our experience, laparoscopy has not been abandoned in favor of the robot: we continue to perform both approaches choosing upon single patient’s characteristics.
Literature
1.
go back to reference Merchant NB, Parikh AA, Kooby DA (2009) Should all distal pancreatectomies be performed laparoscopically? Adv Surg 43:283–300CrossRefPubMed Merchant NB, Parikh AA, Kooby DA (2009) Should all distal pancreatectomies be performed laparoscopically? Adv Surg 43:283–300CrossRefPubMed
2.
go back to reference Milone L, Daskalaki D, Wang X, Giulianotti PC (2013) State of the art of robotic pancreatic surgery. World J Surg 37:2761–2770CrossRefPubMed Milone L, Daskalaki D, Wang X, Giulianotti PC (2013) State of the art of robotic pancreatic surgery. World J Surg 37:2761–2770CrossRefPubMed
3.
go back to reference Venkat R et al (2012) Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg 255:1048–1059CrossRefPubMed Venkat R et al (2012) Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg 255:1048–1059CrossRefPubMed
5.
go back to reference Nigri GR et al (2011) Metaanalysis of trials comparing minimally invasive and open distal pancreatectomies. Surg Endosc 25:1642–1651CrossRefPubMed Nigri GR et al (2011) Metaanalysis of trials comparing minimally invasive and open distal pancreatectomies. Surg Endosc 25:1642–1651CrossRefPubMed
6.
go back to reference Marangos IP et al (2012) Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival. Surgery 151:717–723CrossRefPubMed Marangos IP et al (2012) Laparoscopic resection of exocrine carcinoma in central and distal pancreas results in a high rate of radical resections and long postoperative survival. Surgery 151:717–723CrossRefPubMed
7.
go back to reference Kang CM, Lee SH, Lee WJ (2014) Minimally invasive radical pancreatectomy for left-sided pancreatic cancer: current status and future perspectives. World J Gastroenterol 20:2343–2351PubMedCentralCrossRefPubMed Kang CM, Lee SH, Lee WJ (2014) Minimally invasive radical pancreatectomy for left-sided pancreatic cancer: current status and future perspectives. World J Gastroenterol 20:2343–2351PubMedCentralCrossRefPubMed
8.
go back to reference Kang CM, Kim DH, Lee WJ (2010) Ten years of experience with resection of left-sided pancreatic ductal adenocarcinoma: evolution and initial experience to a laparoscopic approach. Surg Endosc 24:1533–1541CrossRefPubMed Kang CM, Kim DH, Lee WJ (2010) Ten years of experience with resection of left-sided pancreatic ductal adenocarcinoma: evolution and initial experience to a laparoscopic approach. Surg Endosc 24:1533–1541CrossRefPubMed
9.
go back to reference Fernandez-Cruz L et al (2007) Curative laparoscopic resection for pancreatic neoplasms: a critical analysis from a single institution. J Gastrointest Surg 11:1607–1621 discussion 1621-1602CrossRefPubMed Fernandez-Cruz L et al (2007) Curative laparoscopic resection for pancreatic neoplasms: a critical analysis from a single institution. J Gastrointest Surg 11:1607–1621 discussion 1621-1602CrossRefPubMed
10.
go back to reference Song KB et al (2011) Single-center experience of laparoscopic left pancreatic resection in 359 consecutive patients: changing the surgical paradigm of left pancreatic resection. Surg Endosc 25:3364–3372CrossRefPubMed Song KB et al (2011) Single-center experience of laparoscopic left pancreatic resection in 359 consecutive patients: changing the surgical paradigm of left pancreatic resection. Surg Endosc 25:3364–3372CrossRefPubMed
11.
go back to reference Hu M et al (2014) Laparoscopic versus open distal splenopancreatectomy for the treatment of pancreatic body and tail cancer: a retrospective, mid-term follow-up study at a single academic tertiary care institution. Surg Endosc 28:2584–2591CrossRefPubMed Hu M et al (2014) Laparoscopic versus open distal splenopancreatectomy for the treatment of pancreatic body and tail cancer: a retrospective, mid-term follow-up study at a single academic tertiary care institution. Surg Endosc 28:2584–2591CrossRefPubMed
12.
go back to reference Daouadi M et al (2013) Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique. Ann Surg 257:128–132CrossRefPubMed Daouadi M et al (2013) Robot-assisted minimally invasive distal pancreatectomy is superior to the laparoscopic technique. Ann Surg 257:128–132CrossRefPubMed
13.
go back to reference Melvin WS, Needleman BJ, Krause KR, Ellison EC (2003) Robotic resection of pancreatic neuroendocrine tumor. J Laparoendosc Adv Surg Tech Part A 13:33–36CrossRef Melvin WS, Needleman BJ, Krause KR, Ellison EC (2003) Robotic resection of pancreatic neuroendocrine tumor. J Laparoendosc Adv Surg Tech Part A 13:33–36CrossRef
14.
go back to reference Giulianotti PC et al (2003) Robotics in general surgery: personal experience in a large community hospital. Arch Surg 138:777–784CrossRefPubMed Giulianotti PC et al (2003) Robotics in general surgery: personal experience in a large community hospital. Arch Surg 138:777–784CrossRefPubMed
15.
go back to reference Zeh HJ 3rd, Bartlett DL, Moser AJ (2011) Robotic-assisted major pancreatic resection. Adv Surg 45:323–340CrossRefPubMed Zeh HJ 3rd, Bartlett DL, Moser AJ (2011) Robotic-assisted major pancreatic resection. Adv Surg 45:323–340CrossRefPubMed
16.
go back to reference Giulianotti PC et al (2010) Robot-assisted laparoscopic pancreatic surgery: single-surgeon experience. Surg Endosc 24:1646–1657CrossRefPubMed Giulianotti PC et al (2010) Robot-assisted laparoscopic pancreatic surgery: single-surgeon experience. Surg Endosc 24:1646–1657CrossRefPubMed
17.
go back to reference Kim DH, Kang CM, Lee WJ, Chi HS (2011) The first experience of robot assisted spleen-preserving laparoscopic distal pancreatectomy in Korea. Yonsei Med J 52:539–542PubMedCentralCrossRefPubMed Kim DH, Kang CM, Lee WJ, Chi HS (2011) The first experience of robot assisted spleen-preserving laparoscopic distal pancreatectomy in Korea. Yonsei Med J 52:539–542PubMedCentralCrossRefPubMed
18.
go back to reference Kimura W et al (2010) Spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein: techniques and its significance. J Hepatobiliary Pancreat Sci 17:813–823CrossRefPubMed Kimura W et al (2010) Spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein: techniques and its significance. J Hepatobiliary Pancreat Sci 17:813–823CrossRefPubMed
20.
go back to reference Bassi C et al (2005) Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138:8–13CrossRefPubMed Bassi C et al (2005) Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138:8–13CrossRefPubMed
21.
go back to reference Wente MN et al (2007) Postpancreatectomy hemorrhage (PPH): an international study group of pancreatic surgery (ISGPS) definition. Surgery 142:20–25CrossRefPubMed Wente MN et al (2007) Postpancreatectomy hemorrhage (PPH): an international study group of pancreatic surgery (ISGPS) definition. Surgery 142:20–25CrossRefPubMed
22.
go back to reference Clavien PA et al (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250:187–196CrossRefPubMed Clavien PA et al (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250:187–196CrossRefPubMed
23.
24.
go back to reference Kang CM, Kim DH, Lee WJ, Chi HS (2011) Conventional laparoscopic and robot-assisted spleen-preserving pancreatectomy: does da Vinci have clinical advantages? Surg Endosc 25:2004–2009CrossRefPubMed Kang CM, Kim DH, Lee WJ, Chi HS (2011) Conventional laparoscopic and robot-assisted spleen-preserving pancreatectomy: does da Vinci have clinical advantages? Surg Endosc 25:2004–2009CrossRefPubMed
25.
go back to reference Ricci C et al (2015) Laparoscopic distal pancreatectomy: what factors are related to the learning curve? Surg Today 45:50–56CrossRefPubMed Ricci C et al (2015) Laparoscopic distal pancreatectomy: what factors are related to the learning curve? Surg Today 45:50–56CrossRefPubMed
26.
go back to reference Braga M et al (2012) Learning curve for laparoscopic distal pancreatectomy in a high-volume hospital. Updat Surg 64:179–183CrossRef Braga M et al (2012) Learning curve for laparoscopic distal pancreatectomy in a high-volume hospital. Updat Surg 64:179–183CrossRef
27.
go back to reference Zureikat AH et al (2013) 250 robotic pancreatic resections: safety and feasibility. Ann Surg 258:554–559 discussion 559-562PubMed Zureikat AH et al (2013) 250 robotic pancreatic resections: safety and feasibility. Ann Surg 258:554–559 discussion 559-562PubMed
28.
go back to reference Zhou W et al (2010) Stapler vs suture closure of pancreatic remnant after distal pancreatectomy: a meta-analysis. Am J Surg 200:529–536CrossRefPubMed Zhou W et al (2010) Stapler vs suture closure of pancreatic remnant after distal pancreatectomy: a meta-analysis. Am J Surg 200:529–536CrossRefPubMed
29.
go back to reference Eguchi H et al (2011) A thick pancreas is a risk factor for pancreatic fistula after a distal pancreatectomy: selection of the closure technique according to the thickness. Dig Surg 28:50–56CrossRefPubMed Eguchi H et al (2011) A thick pancreas is a risk factor for pancreatic fistula after a distal pancreatectomy: selection of the closure technique according to the thickness. Dig Surg 28:50–56CrossRefPubMed
30.
go back to reference Hanna EM et al (2013) Robotic hepatobiliary and pancreatic surgery: lessons learned and predictors for conversion. Int J Med Robot Comput Assist Surg 9:152–159CrossRef Hanna EM et al (2013) Robotic hepatobiliary and pancreatic surgery: lessons learned and predictors for conversion. Int J Med Robot Comput Assist Surg 9:152–159CrossRef
31.
go back to reference Hwang HK et al (2013) Robot-assisted spleen-preserving distal pancreatectomy: a single surgeon’s experiences and proposal of clinical application. Surg Endosc 27:774–781CrossRefPubMed Hwang HK et al (2013) Robot-assisted spleen-preserving distal pancreatectomy: a single surgeon’s experiences and proposal of clinical application. Surg Endosc 27:774–781CrossRefPubMed
33.
go back to reference Dalla Bona E, Beltrame V, Liessi F, Sperti C (2012) Fatal pneumococcal sepsis eleven years after distal pancreatectomy with splenectomy for pancreatic cancer. JOP 13:693–695PubMed Dalla Bona E, Beltrame V, Liessi F, Sperti C (2012) Fatal pneumococcal sepsis eleven years after distal pancreatectomy with splenectomy for pancreatic cancer. JOP 13:693–695PubMed
34.
go back to reference Magge D et al (2013) Comparative effectiveness of minimally invasive and open distal pancreatectomy for ductal adenocarcinoma. JAMA Surg 148:525–531CrossRefPubMed Magge D et al (2013) Comparative effectiveness of minimally invasive and open distal pancreatectomy for ductal adenocarcinoma. JAMA Surg 148:525–531CrossRefPubMed
35.
go back to reference Duran H et al (2014) Does robotic distal pancreatectomy surgery offer similar results as laparoscopic and open approach? A comparative study from a single medical center. Int J Med Robot Comput Assist Surg 10:280–285CrossRef Duran H et al (2014) Does robotic distal pancreatectomy surgery offer similar results as laparoscopic and open approach? A comparative study from a single medical center. Int J Med Robot Comput Assist Surg 10:280–285CrossRef
36.
go back to reference Heemskerk J, Bouvy ND, Baeten CG (2014) The end of robot-assisted laparoscopy? A critical appraisal of scientific evidence on the use of robot-assisted laparoscopic surgery. Surg Endosc 28:1388–1398CrossRefPubMed Heemskerk J, Bouvy ND, Baeten CG (2014) The end of robot-assisted laparoscopy? A critical appraisal of scientific evidence on the use of robot-assisted laparoscopic surgery. Surg Endosc 28:1388–1398CrossRefPubMed
Metadata
Title
A prospective non-randomised single-center study comparing laparoscopic and robotic distal pancreatectomy
Authors
Giovanni Butturini
Isacco Damoli
Lorenzo Crepaz
Giuseppe Malleo
Giovanni Marchegiani
Despoina Daskalaki
Alessandro Esposito
Sara Cingarlini
Roberto Salvia
Claudio Bassi
Publication date
01-11-2015
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 11/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-4043-3

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