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Published in: Surgical Endoscopy 9/2008

Open Access 01-09-2008

Timing of cholecystectomy after endoscopic sphincterotomy for common bile duct stones

Authors: Anandi H. W. Schiphorst, Marc G. H. Besselink, Djamila Boerma, Robin Timmer, Marinus J. Wiezer, Karel J. van Erpecum, Ivo A. M. J. Broeders, Bert van Ramshorst

Published in: Surgical Endoscopy | Issue 9/2008

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Abstract

Background

According to the literature, the conversion rate for laparoscopic cholecystectomy (LC) after endoscopic sphincterotomy (ES) for cholecystodocholithiasis reaches 20%, at least when LC is performed 6 to 8 weeks afterward. It is hypothesized that early planned LC after ES prevents recurrent biliary complications and reduces operative morbidity and hospital stay.

Methods

All consecutive patients who underwent LC after ES between 2001 and 2004 were retrospectively evaluated. Recurrent biliary complications during the waiting time for LC, conversion rate, postoperative complications, and hospital stay were documented.

Results

This study analyzed 167 consecutive patients (59 men) with a median age of 54 years. The median interval between ES and LC was 7 weeks (range, 1–49 weeks). During the waiting time for LC, 33 patients (20%) had recurrent biliary complications including cholecystitis (n = 18, 11%), recurrent choledocholithiasis (n = 9, 5%), cholangitis (n = 4, 2%), and biliary pancreatitis (n = 2, 1%). Of these 33 patients, 15 underwent a second endoscopic retrograde cholangiography (ERC). The median time between ES and the development of recurrent complications was 22 days (range, 3–225 days). Most of the biliary complications (76%) occurred more than 1 week after ES. Conversion to open cholecystectomy occurred for 7 of 33 patients with recurrent complications during the waiting period, compared with 13 of 134 patients with an uncomplicated waiting period (p = 0.14). This concurred with doubled postoperative morbidity (24% vs 11%; p = 0.09) and a longer hospital stay (median, 4 vs 2 days; p < 0.001).

Conclusion

In this retrospective analysis, 20% of all patients had recurrent biliary complications during the waiting period for cholecystectomy after ES. These recurrent complications were associated with a significantly longer hospital stay. Cholecystectomy within 1 week after ES may prevent recurrent biliary complications in the majority of cases and reduce the postoperative hospital stay.
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Metadata
Title
Timing of cholecystectomy after endoscopic sphincterotomy for common bile duct stones
Authors
Anandi H. W. Schiphorst
Marc G. H. Besselink
Djamila Boerma
Robin Timmer
Marinus J. Wiezer
Karel J. van Erpecum
Ivo A. M. J. Broeders
Bert van Ramshorst
Publication date
01-09-2008
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 9/2008
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-008-9764-8

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