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Surgical Endoscopy
Published in: Surgical Endoscopy 9/2005

01-09-2005 | Original Article

Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer

Authors: H. Hayashi, T. Ochiai, H. Shimada, Y. Gunji

Published in: Surgical Endoscopy | Issue 9/2005

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Abstract

Background

Laparoscopy-assisted surgery with extraperigastric lymph node dissection for gastric cancers has been described, but the clinical benefits of these surgeries still are unclear. Short-term clinical outcomes were compared between laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for early gastric cancer in a prospective randomized fashion.

Methods

For this study, 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG (n = 4) or ODG (n = 14). Postoperative pain, levels of acute inflammatory responses, and pathologic evaluation of the operative specimens were compared.

Results

The LADG group required a significantly shorter period of postoperative epidural anesthesia, showed significantly lower levels of serum interleukin-6 and C-reactive protein, and had no major postsurgery complications. Pathologic examinations showed that surgery was equally radical in the two groups.

Conclusion

The findings show that LADG with extraperigastric lymph node dissection is a safe and less invasive alternative to the open procedure.
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Metadata
Title
Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer
Authors
H. Hayashi
T. Ochiai
H. Shimada
Y. Gunji
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
Surgical Endoscopy / Issue 9/2005
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-004-8207-4

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