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Open Access 01-08-2021 | Climate Change | Review and Perspectives

Basic principles of biobanking: from biological samples to precision medicine for patients

Authors: Laura Annaratone, Giuseppe De Palma, Giuseppina Bonizzi, Anna Sapino, Gerardo Botti, Enrico Berrino, Chiara Mannelli, Pamela Arcella, Simona Di Martino, Agostino Steffan, Maria Grazia Daidone, Vincenzo Canzonieri, Barbara Parodi, Angelo Virgilio Paradiso, Massimo Barberis, Caterina Marchiò, On behalf of Alleanza Contro il Cancro (ACC) Pathology and Biobanking Working Group

Published in: Virchows Archiv | Issue 2/2021

Abstract

The term “biobanking” is often misapplied to any collection of human biological materials (biospecimens) regardless of requirements related to ethical and legal issues or the standardization of different processes involved in tissue collection. A proper definition of biobanks is large collections of biospecimens linked to relevant personal and health information (health records, family history, lifestyle, genetic information) that are held predominantly for use in health and medical research. In addition, the International Organization for Standardization, in illustrating the requirements for biobanking (ISO 20387:2018), stresses the concept of biobanks being legal entities driving the process of acquisition and storage together with some or all of the activities related to collection, preparation, preservation, testing, analysing and distributing defined biological material as well as related information and data. In this review article, we aim to discuss the basic principles of biobanking, spanning from definitions to classification systems, standardization processes and documents, sustainability and ethical and legal requirements. We also deal with emerging specimens that are currently being generated and shaping the so-called next-generation biobanking, and we provide pragmatic examples of cancer-associated biobanking by discussing the process behind the construction of a biobank and the infrastructures supporting the implementation of biobanking in scientific research.

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Title: Basic principles of biobanking: from biological samples to precision medicine for patients
Authors: Laura Annaratone
Giuseppe De Palma
Giuseppina Bonizzi
Anna Sapino
Gerardo Botti
Enrico Berrino
Chiara Mannelli
Pamela Arcella
Simona Di Martino
Agostino Steffan
Maria Grazia Daidone
Vincenzo Canzonieri
Barbara Parodi
Angelo Virgilio Paradiso
Massimo Barberis
Caterina Marchiò
On behalf of Alleanza Contro il Cancro (ACC) Pathology and Biobanking Working Group
Publication date: 01-08-2021
Publisher: Springer Berlin Heidelberg
Keyword: Climate Change
Published in: Virchows Archiv / Issue 2/2021
Print ISSN: 0945-6317
Electronic ISSN: 1432-2307
DOI: https://doi.org/10.1007/s00428-021-03151-0

At a glance: The STEP trials

Springer Medicine

Basic principles of biobanking: from biological samples to precision medicine for patients

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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