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Langenbeck's Archives of Surgery

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01-12-2018 | ORIGINAL ARTICLE

Supraclavicular and celiac metastases in squamous cell carcinoma of the middle thoracic esophagus

Authors: Akihiko Okamura, Masayuki Watanabe, Ryotaro Kozuki, Tasuku Toihata, Masami Yuda, Yu Imamura, Shinji Mine

Published in: Langenbeck's Archives of Surgery | Issue 8/2018

Abstract

Purpose

Squamous cell carcinoma of the middle thoracic esophagus (SCC-ME) often metastasizes to the neck, mediastinum, and abdomen. This study aims to assess the prognostic impact of supraclavicular (SC) and celiac (CE) lymph node (LN) metastases in patients with SCC-ME.

Methods

We examined 210 patients who underwent curative esophagectomy with three-field LN dissection for SCC-ME. The clinicopathological features and survival outcomes of patients with and without SC and/or CE metastases were compared to assess the prognostic significance of SC and/or CE metastases.

Results

We observed metastases to SC and CE in 25 (11.9%) and 20 (9.5%) patients, respectively. Seven patients (3.3%) had both SC and CE metastases. Although the survival of patients with SC and/or CE metastases was worse compared with those without, that of patients with SC metastases but without CE metastases was comparable with that of patients with CE metastases but without SC metastases; the 5 year overall survival rates were 35.6% and 46.2%, respectively. However, survival of patients with both SC and CE metastases was the worst among all groups, and all patients with both SC and CE metastases experienced disease recurrence.

Conclusions

The prognosis of patients with both SC and CE metastases was extremely poor. In contrast, patients with metastasis to either one of these sites could be candidates for surgery as the main modality in a multidisciplinary strategy.

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Title: Supraclavicular and celiac metastases in squamous cell carcinoma of the middle thoracic esophagus
Authors: Akihiko Okamura
Masayuki Watanabe
Ryotaro Kozuki
Tasuku Toihata
Masami Yuda
Yu Imamura
Shinji Mine
Publication date: 01-12-2018
Publisher: Springer Berlin Heidelberg
Published in: Langenbeck's Archives of Surgery / Issue 8/2018
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-018-1722-x

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Supraclavicular and celiac metastases in squamous cell carcinoma of the middle thoracic esophagus

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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