Preoperative prognostic factors for severe diffuse secondary peritonitis: a retrospective study

A total of 223 patients were analysed. Overall 30-day mortality was 14.5 %. Postoperatively, 32.3 % of patients were admitted into the intensive care unit (ICU). Independent risk factors for severe peritonitis were septic shock (odds ratio (OR) 37.94, 95 % confidence interval (CI) 14.52–99.13), chronic kidney insufficiency (OR 5.98 (95 % CI 1.56–22.86), severe sepsis (OR 4.80, 95 % CI 2.10–10.65) and cardiovascular disease (OR 2.58, 95 % CI 1.22–5.47). Patients lacking these factors had no mortality. ICU admission was refused in 24 (10.8 %) patients with 70.8 % mortality. In a subgroup of patients without treatment limitations (n = 190), independent risk factors for weighted outcome of ICU admission or mortality were septic shock (OR 11.89, 95 % CI 4.98–28.40), severe sepsis (OR 5.56, 95 % CI 2.39–12.89), metastatic malignant disease or lymphoma (OR 3.11, 95 % CI 1.34–7.20) and corticosteroid use (OR 2.98, 95 % CI 1.18–7.51). When receiving full level of care, patients with preoperative organ dysfunctions in this subgroup had 8.2 % 30-day mortality.