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Langenbeck's Archives of Surgery

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01-06-2016 | ORIGINAL ARTICLE

Major hepatopancreatoduodenectomy with simultaneous resection of the hepatic artery for advanced biliary cancer

Authors: Yasuyuki Fukami, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Shunsuke Onoe

Published in: Langenbeck's Archives of Surgery | Issue 4/2016

Abstract

Background

Major hepatopancreatoduodenectomy (HPD) with simultaneous resection of the hepatic artery (HA) for biliary cancer is the most extended surgery for obtaining curative resection, and its clinical significance is unclear. The aim of this study was to appraise the clinical value of this extended procedure as a treatment for biliary cancer.

Methods

We retrospectively reviewed the medical records of 38 patients with biliary cancer who underwent major HPD from 1994 to 2014. Clinicopathological factors and survival following HPD were compared between patients with and without simultaneous resection of the HA.

Results

Of the 38 study patients, 12 patients (32 %) underwent major HPD with HA. There was no significant difference in major complications between the two groups. The overall 2-year survival rate and the median survival time following major HPD with HA were 71 % and 42.3 months. The survival of the patients with gallbladder cancer was significantly worse than that of the patients with bile duct cancer (p = 0.001).

Conclusions

Major HPD with simultaneous resection of the HA can be a preferable treatment option for bile duct cancer that offers acceptable perioperative morbidity and mortality, as well as long-term survival. However, this procedure for gallbladder cancer should not be performed.

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Title: Major hepatopancreatoduodenectomy with simultaneous resection of the hepatic artery for advanced biliary cancer
Authors: Yasuyuki Fukami
Yuji Kaneoka
Atsuyuki Maeda
Yuichi Takayama
Shunsuke Onoe
Publication date: 01-06-2016
Publisher: Springer Berlin Heidelberg
Published in: Langenbeck's Archives of Surgery / Issue 4/2016
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-016-1413-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Major hepatopancreatoduodenectomy with simultaneous resection of the hepatic artery for advanced biliary cancer

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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