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Published in:

01-07-2008

Value of Multidetector-row Computed Tomography in Diagnosis of Portal Vein Invasion by Perihilar Cholangiocarcinoma

Authors: Teiichi Sugiura, Hideki Nishio, Masato Nagino, Yoshiki Senda, Tomoki Ebata, Yukihiro Yokoyama, Tsuyoshi Igami, Koji Oda, Yuji Nimura

Published in: World Journal of Surgery | Issue 7/2008

Abstract

Background

Although knowledge of cancer invasion of the portal bifurcation is vitally important in planning an operation for perihilar cholangiocarcinoma, the diagnostic capability of multidetector-row computed tomography (MDCT) for this purpose has not been assessed. We evaluated how well MDCT could identify cancer invasion of the portal bifurcation by perihilar cholangiocarcinoma.

Methods

Between April 2003 and June 2005, perihilar cholangiocarcinoma was resected in 87 patients, 83 of whom underwent MDCT within 1 month before the surgery. Three-dimensional volume-rendered (3DVR) and multiplanar reformation (MPR) images were examined for evidence of portal vein invasion. Agreement with intraoperative and pathologic findings was assessed. Portal bifurcation findings by 3DVR and MPR were classified into no portal vein stenosis, unilateral stenosis, or more extensive stenosis, and also into tumor contact with the bifurcation in no, one of two, or two projections.

Results

For macroscopic portal vein invasion, sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy were 81.5, 91.1, 81.5, 91.1, and 88.0% in 3D portography and 96.3, 92.6, 86.7, 98.1, and 94.0% in MPR, respectively. Findings by both 3DVR and MPR were significantly correlated with depth of cancer invasion (p < 0.001).

Conclusion

MDCT is useful in assessing cancer invasion of the portal vein bifurcation by perihilar cholangiocarcinoma.

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Title: Value of Multidetector-row Computed Tomography in Diagnosis of Portal Vein Invasion by Perihilar Cholangiocarcinoma
Authors: Teiichi Sugiura
Hideki Nishio
Masato Nagino
Yoshiki Senda
Tomoki Ebata
Yukihiro Yokoyama
Tsuyoshi Igami
Koji Oda
Yuji Nimura
Publication date: 01-07-2008
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 7/2008
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-008-9547-3

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Value of Multidetector-row Computed Tomography in Diagnosis of Portal Vein Invasion by Perihilar Cholangiocarcinoma

Abstract

Background

Methods

Results

Conclusion

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