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01-07-2015 | Original Article

Body mass index and ghrelin levels after laparoscopic Nissen fundoplication

Authors: Taner Yigit, Ali Kagan Coskun, Ali Harlak, Huseyin Sinan, Aytekin Unlu, Serkan Tapan, Emin Lapsekili, Orhan Kozak

Published in: Langenbeck's Archives of Surgery | Issue 5/2015

Abstract

Purpose

The study aims to evaluate the changes between body mass index (BMI) and ghrelin levels after laparoscopic Nissen fundoplication (LNF).

Methods

Twenty-four consecutive patients with gastroesophageal reflux disease who were scheduled for LNF consented to participate in the study. The participants’ age, sex, preoperative (phase 0), postoperative 1st week (phase 1) and postoperative 4th week (phase 2) dysphagia scores, plasma ghrelin levels, and BMI were recorded.

Results

Compared to the preoperative level (phase 0), ghrelin was decreased in both phase 1 and phase 2. A strong correlation in the changes in the ghrelin values and BMI between phase 0 and phase 2 was detected. There was a strong, statistically significant difference in the changes in the BMI values between phase 1 and phase 2.

Conclusions

Total plication of the fundus impairs its ghrelin-secreting functions for up to 4 weeks and is accompanied by weight loss.

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Title: Body mass index and ghrelin levels after laparoscopic Nissen fundoplication
Authors: Taner Yigit
Ali Kagan Coskun
Ali Harlak
Huseyin Sinan
Aytekin Unlu
Serkan Tapan
Emin Lapsekili
Orhan Kozak
Publication date: 01-07-2015
Publisher: Springer Berlin Heidelberg
Published in: Langenbeck's Archives of Surgery / Issue 5/2015
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI: https://doi.org/10.1007/s00423-015-1315-x

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Body mass index and ghrelin levels after laparoscopic Nissen fundoplication

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on sleep in brain health

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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