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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 4/2021

01-04-2021 | Edema | Review Article

Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema

Authors: Shigeo Yoshida, Tomoaki Murakami, Miho Nozaki, Kiyoshi Suzuma, Takayuki Baba, Takao Hirano, Osamu Sawada, Masahiko Sugimoto, Yoshihiro Takamura, Eiko Tsuiki

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 4/2021

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Abstract

Diabetic macular edema (DME), characterized by exudative fluid accumulation in the macula, is the most common form of sight-threatening retinopathy in patients with diabetes. The management of DME has changed considerably in recent years, especially following the development of intravitreal anti-vascular endothelial growth factor therapy which has emerged as a first-line therapy for center-involved DME. Laser treatment, intravitreal steroid therapy, and vitrectomy are also important treatment options for DME. We believe that it is important to choose the most appropriate treatment option for DME based on the clinical evidences, in addition to the careful consideration of individual patients’ general or ocular condition, DME characteristics, patients’ motivation, and compliance to the treatment in real-world clinical practice. In this review, we have summarized important clinical evidences for the main treatments for DME, presented an expert review for these evidences, and proposed a recommended therapeutic flow chart for DME. We hope that our review of the clinical evidences and the recommended therapeutic flow chart for DME will contribute to better treatment outcome for DME.
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Metadata
Title
Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema
Authors
Shigeo Yoshida
Tomoaki Murakami
Miho Nozaki
Kiyoshi Suzuma
Takayuki Baba
Takao Hirano
Osamu Sawada
Masahiko Sugimoto
Yoshihiro Takamura
Eiko Tsuiki
Publication date
01-04-2021
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 4/2021
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-020-04936-w

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