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Published in: Graefe's Archive for Clinical and Experimental Ophthalmology 9/2009

01-09-2009 | Cataract

Lens capsular bag irrigation for low-grade endophthalmitis

Authors: Frank C. Schlichtenbrede, Ulrich H. M. Spandau, Björn Harder, Jost B. Jonas

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 9/2009

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Abstract

Purpose

In postoperative low-grade endophthalmitis, microorganisms of low pathogenicity exhibit prolonged survival times by sequestration into the capsular bag. Thus, removal or irrigation of the capsular bag as nidus of the microorganisms is an essential therapeutic step. Correspondingly, guidelines suggest pars plana vitrectomy, capsulectomy and/or intraocular lens removal. Here, we report on capsular bag irrigation alone as an alternative, minimally invasive therapeutic method for postoperative infectious low-grade endophthalmitis.

Methods

Nine patients consecutively presenting with whitish precipitates in the capsular bag, anterior chamber inflammation and mild vitritis 2 weeks to 6 months following uncomplicated cataract surgery were included. Using an irrigation/aspiration cannula, synechiae were opened, the intraocular lens was rotated within the intact capsular bag and irrigated with 30 ml Ringer’s solution containing 0.16 mg/ml gentamicin and 0.04 mg/ml vancomycin in topical anaesthesia.

Results

In all patients, the inflammation subsided within 2 days to 2 weeks. Visual acuity improved in all patients, mostly to post cataract surgery levels. Visual acuity remained stable during follow-up ranging from 2 to 39 months. No further interventions were required.

Conclusions

The results suggest that capsular bag irrigation as first and single surgical step can be a useful, minimally invasive procedure in the surgical armamentarium for the treatment of infectious low-grade endophthalmitis. It may avoid removal of the intraocular lens and reduce the surgical risks of more complex procedures.
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Metadata
Title
Lens capsular bag irrigation for low-grade endophthalmitis
Authors
Frank C. Schlichtenbrede
Ulrich H. M. Spandau
Björn Harder
Jost B. Jonas
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 9/2009
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-009-1085-7

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