Top

Published in:

Open Access 01-12-2020 | Vestibular Schwannoma | Review

The “hype” of hydrops in classifying vestibular disorders: a narrative review

Authors: Marly F. J. A. van der Lubbe, Akshayaa Vaidyanathan, Vincent Van Rompaey, Alida A. Postma, Tjasse D. Bruintjes, Dorien M. Kimenai, Philippe Lambin, Marc van Hoof, Raymond van de Berg

Published in: Journal of Neurology | Special Issue 1/2020

Abstract

Background

Classifying and diagnosing peripheral vestibular disorders based on their symptoms is challenging due to possible symptom overlap or atypical clinical presentation. To improve the diagnostic trajectory, gadolinium-based contrast-enhanced magnetic resonance imaging of the inner ear is nowadays frequently used for the in vivo confirmation of endolymphatic hydrops in humans. However, hydrops is visualized in both healthy subjects and patients with vestibular disorders, which might make the clinical value of hydrops detection on MRI questionable.

Objective

To investigate the diagnostic value of clinical and radiological features, including the in vivo visualization of endolymphatic hydrops, for the classification and diagnosis of vestibular disorders.

Methods

A literature search was performed in February and March 2019 to estimate the prevalence of various features in healthy subjects and in common vestibular disorders to make a graphical comparison between healthy and abnormal.

Results

Of the features studied, hydrops was found to be a highly prevalent feature in Menière’s disease (99.4%). Though, hydrops has also a relatively high prevalence in patients with vestibular schwannoma (48.2%) and in healthy temporal bones (12.5%) as well. In patients diagnosed with (definite or probable) Menière’s disease, hydrops is less frequently diagnosed by magnetic resonance imaging compared to the histological confirmation (82.3% versus 99.4%). The mean prevalence of radiologically diagnosed hydrops was 31% in healthy subjects, 28.1% in patients with vestibular migraine, and 25.9% in patients with vestibular schwannoma. An interesting finding was an absolute difference in hydrops prevalence between the two diagnostic techniques (histology and radiology) of 25.2% in patients with Menière’s disease and 29% in patients with vestibular schwannoma.

Conclusions

Although the visualization of hydrops has a high diagnostic value in patients with definite Menière’s disease, it is important to appreciate the relatively high prevalence of hydrops in healthy populations and other vestibular disorders. Endolymphatic hydrops is not a pathognomic phenomenon, and detecting hydrops should not directly indicate a diagnosis of Menière’s disease. Both symptom-driven and hydrops-based classification systems have disadvantages. Therefore, it might be worth to explore features “beyond” hydrops. New analysis techniques, such as Radiomics, might play an essential role in (re)classifying vestibular disorders in the future.

Available only for authorised users

Bisdorff A, Von Brevern M, Lempert T, Newman-Toker DE (2009) Classification of vestibular symptoms: towards an international classification of vestibular disorders. J Vestib Res Equilib Orientat. https://doi.org/10.3233/VES-2009-0343CrossRef

Bisdorff AR, Staab JP, Newman-Toker DE (2015) Overview of the international classification of vestibular disorders. Clin Neurol. https://doi.org/10.1016/j.ncl.2015.04.010CrossRef

Foster CA, Breeze RE (2013) Endolymphatic hydrops in Ménière’s disease: cause, consequence, or epiphenomenon? Otol Neurotol. https://doi.org/10.1097/MAO.0b013e31829e83dfCrossRefPubMed

Lopez-Escamez JA, Carey J, Chung WH et al (2015) Diagnostic criteria for Menière’s disease. J Vestib Res Equilib Orientat. https://doi.org/10.3233/VES-150549CrossRef

Loscalzo J, Kohane I, Barabasi AL (2007) Human disease classification in the postgenomic era: a complex systems approach to human pathobiology. Syst Biol Mol. https://doi.org/10.1038/msb4100163CrossRef

Naganawa S, Nakashima T (2014) Visualization of endolymphatic hydrops with MR imaging in patients with Ménière’s disease and related pathologies: current status of its methods and clinical significance. J Radiol Jpn. https://doi.org/10.1007/s11604-014-0390-4CrossRef

Abele TA, Wiggins RH (2015) Imaging of the temporal bone. Clin North Am Radiol. https://doi.org/10.1016/j.rcl.2014.09.010CrossRef

Gürkov R, Hornibrook J (2018) On the classification of hydropic ear disease (Menière’s disease). HNO. https://doi.org/10.1007/s00106-018-0488-3CrossRefPubMed

Merchant SN, Adams JC, Nadol JB (2005) Pathophysiology of Ménière’s syndrome: are symptoms caused by endolymphatic hydrops? Otol Neurotol 3:5

10.

Noruzi A (2005) Google scholar: the new generation of citation indexes. Libri. https://doi.org/10.1515/LIBR.2005.170CrossRef

11.

Baráth K, Schuknecht B, Monge Naldi A et al (2014) Detection and grading of endolymphatic hydrops in Menière disease using MR imaging. Am J Neuroradiol. https://doi.org/10.3174/ajnr.A3856CrossRefPubMed

12.

Sun W, Guo P, Ren T, Wang W (2017) Magnetic resonance imaging of intratympanic gadolinium helps differentiate vestibular migraine from Ménière disease. Laryngoscope. https://doi.org/10.1002/lary.26518CrossRefPubMed

13.

Nakashima T, Naganawa S, Pyykkö I et al (2009) Grading of endolymphatic hydrops using magnetic resonance imaging. Acta Oto Laryngol. https://doi.org/10.1080/00016480902729827CrossRef

14.

Conte G, Russo FM, Calloni SF et al (2018) MR imaging of endolymphatic hydrops in Ménière’s disease. not all that glitters is gold. Acta Otorhinolaryngol Ital. https://doi.org/10.14639/0392-100X-1986CrossRefPubMedPubMedCentral

15.

Carson S, Chris P, Toby H, et al (2016) plotly: create interactive web graphics via ‘plotly. js.’ R Packag version

16.

Goebel JA (2016) 2015 Equilibrium Committee amendment to the 1995 AAO-HNS guidelines for the definition of Ménière’s disease. Otolaryngol Head Neck Surg (United States). https://doi.org/10.1177/0194599816628524CrossRef

17.

Lempert T, Olesen J, Furman J et al (2012) Vestibular migraine: Diagnostic criteria. J Vestib Res Equilib Orientat. https://doi.org/10.3233/VES-2012-0453CrossRef

18.

Karch-Georges A, Veillon F, Vuong H et al (2019) MRI of endolymphatic hydrops in patients with vestibular schwannomas: a case-controlled study using non-enhanced T2-weighted images at 3 Teslas. Eur Arch Oto Rhino Laryngol. https://doi.org/10.1007/s00405-019-05395-8CrossRef

19.

Naganawa S, Kawai H, Sone M et al (2011) Endolympathic hydrops in patients with vestibular schwannoma: visualization by non-contrast-enhanced 3D FLAIR. Neuroradiology. https://doi.org/10.1007/s00234-010-0834-yCrossRefPubMed

20.

Belal A, Antunez JC (1980) Pathology of endolymphatic hydrops. J Laryngol Otol. https://doi.org/10.1017/S0022215100090058CrossRefPubMed

21.

Hlzll Ö, Cureoglu S, Kaya S et al (2016) Quantitative vestibular labyrinthine otopathology in temporal bones with vestibular Schwannoma. Otolaryngol Head Neck Surg (United States). https://doi.org/10.1177/0194599815601070CrossRef

22.

Bachor E, Karmody CS (1995) Endolymphatic hydrops in children. ORL. https://doi.org/10.1159/000276725CrossRefPubMed

23.

Saito H, Takeda T, Kishimoto S, Furuta M (2011) Labyrinthine Anomaly and Endolymphatic Hydrops. In: Ménière’s Disease. Springer, Tokyo

24.

Mahmud MR, Khan AM, Nadol JB (2003) Histopathology of the inner ear in unoperated acoustic neuroma. Ann Otol Rhinol Laryngol. https://doi.org/10.1177/000348940311201111CrossRefPubMed

25.

Conte G, Caschera L, Calloni S et al (2018) MR imaging in menière disease: Is the contact between the vestibular endolymphatic space and the oval window a reliable biomarker? Am J Neuroradiol. https://doi.org/10.3174/ajnr.A5841CrossRefPubMed

26.

Li X, Wu Q, Sha Y et al (2018) Gadolinium-enhanced MRI reveals dynamic development of endolymphatic hydrops in Ménière’s disease. Braz J Otorhinolaryngol Otorhinolaryngol. https://doi.org/10.1016/j.bjorl.2018.10.014CrossRef

27.

Yoshida T, Sugimoto S, Teranishi M et al (2018) Imaging of the endolymphatic space in patients with Ménière’s disease. Auris Nasus Larynx. https://doi.org/10.1016/j.anl.2017.02.002CrossRefPubMed

28.

Morimoto K, Yoshida T, Sugiura S et al (2017) Endolymphatic hydrops in patients with unilateral and bilateral Meniere’s disease. Acta Otolaryngol. https://doi.org/10.1080/00016489.2016.1217042CrossRefPubMed

29.

Ito T, Kitahara T, Inui H et al (2016) Endolymphatic space size in patients with Meniere’s disease and healthy controls. Acta Otolaryngol. https://doi.org/10.3109/00016489.2016.1169556CrossRefPubMed

30.

Wu Q, Dai C, Zhao M, Sha Y (2016) The correlation between symptoms of definite Meniere’s disease and endolymphatic hydrops visualized by magnetic resonance imaging. Laryngoscope. https://doi.org/10.1002/lary.25576CrossRefPubMed

31.

Pyykkö I, Nakashima T, Yoshida T et al (2013) Ménière’s disease: a reappraisal supported by a variable latency of symptoms and the MRI visualisation of endolymphatic hydrops. BMJ Open. https://doi.org/10.1136/bmjopen-2012-001555CrossRefPubMedPubMedCentral

32.

Liu Y, Jia H, Shi J (2015) Endolymphatic hydrops detected by 3-dimensional fluid-attenuated inversion recovery MRI following intratympanic injection of gadolinium in the asymptomatic contralateral ears of patients with unilateral Ménière’s disease. Med Sci Monit. https://doi.org/10.12659/MSM.892383CrossRefPubMedPubMedCentral

33.

Shi S, Guo P, Li W, Wang W (2019) Clinical features and endolymphatic hydrops in patients with MRI evidence of hydrops. Ann Otol Rhinol Laryngol. https://doi.org/10.1177/0003489418819551CrossRefPubMed

34.

Shi S, Guo P, Wang W (2018) Magnetic resonance imaging of Ménière’s disease after intravenous administration of Gadolinium. Ann Otol Rhinol Laryngol. https://doi.org/10.1177/0003489418794699CrossRefPubMed

35.

Committee on Hearing and Equilibrium (1972) Report of subcommittee on equilibrium and its measurement. Meniere’s disease: criteria for diagnosis and evaluation of therapy for reporting. Trans Am Acad Ophthalmol Otolaryngol 4(6):130–678

36.

Nakada T, Yoshida T, Suga K et al (2014) Endolymphatic space size in patients with vestibular migraine and Ménière’s disease. J Neurol. https://doi.org/10.1007/s00415-014-7458-9CrossRefPubMed

37.

Kato M, Sugiura M, Shimono M et al (2013) Endolymphatic hydrops revealed by magnetic resonance imaging in patients with atypical Meniere’s disease. Acta Otolaryngol. https://doi.org/10.3109/00016489.2012.726374CrossRefPubMed

38.

Teranishi M, Naganawa S, Katayama N et al (2009) Image evaluation of endolymphatic space in fluctuating hearing loss without vertigo. Eur Arch Oto Rhino Laryngol. https://doi.org/10.1007/s00405-009-0989-5CrossRef

39.

Attyé A, Eliezer M, Boudiaf N et al (2017) MRI of endolymphatic hydrops in patients with Meniere’s disease: a case-controlled study with a simplified classification based on saccular morphology. Eur Radiol. https://doi.org/10.1007/s00330-016-4701-zCrossRefPubMed

40.

Lopez-Escamez JA, Dlugaiczyk J, Jacobs J et al (2014) Accompanying symptoms overlap during attacks in Menière’s disease and vestibular migraine. Front Neurol. https://doi.org/10.3389/fneur.2014.00265CrossRefPubMedPubMedCentral

41.

Neff BA, Staab JP, Eggers SD et al (2012) Auditory and vestibular symptoms and chronic subjective dizziness in patients with Ménière’s disease, vestibular migraine, and Ménière’s disease with concomitant vestibular migraine. Otol Neurotol. https://doi.org/10.1097/MAO.0b013e31825d644aCrossRefPubMed

42.

Eklund S (1999) Headache in Meniere’s disease. Auris Nasus Larynx. https://doi.org/10.1016/S0385-8146(99)00022-XCrossRefPubMed

43.

Tyrrell JS, Whinney DJD, Ukoumunne OC et al (2014) Prevalence, associated factors, and comorbid conditions for Ménière’s disease. Ear Hear. https://doi.org/10.1097/AUD.0000000000000041CrossRefPubMed

44.

Wang Y, Diao T, Zhao Y, Yu L (2018) The clinical characteristics and audiogram in 103 Meniere’s disease patients with and without vestibular migraine. Clin Otolaryngol. https://doi.org/10.1111/coa.12946CrossRefPubMed

45.

Brantberg K, Baloh RW (2011) Similarity of vertigo attacks due to Meniere’s disease and benign recurrent vertigo, both with and without migraine. Acta Otolaryngol. https://doi.org/10.3109/00016489.2011.556661CrossRefPubMed

46.

Levo H, Kentala E, Rasku J, PyykkF I (2014) Aural Fullness in M3ni2re’s Disease. Audiol Neurotol. https://doi.org/10.1159/000363211CrossRef

47.

Ghavami Y, Mahboubi H, Yau AY et al (2016) Migraine features in patients with Meniere’s disease. Laryngoscope. https://doi.org/10.1002/lary.25344CrossRefPubMedPubMedCentral

48.

Guo P, Sun W, Shi S et al (2019) Quantitative evaluation of endolymphatic hydrops with MRI through intravenous gadolinium administration and VEMP in unilateral definite Meniere’s disease. Eur Arch Oto Rhino Laryngol. https://doi.org/10.1007/s00405-018-05267-7CrossRef

49.

Okazaki Y, Yoshida T, Sugimoto S et al (2017) Significance of endolymphatic hydrops in ears with unilateral sensorineural hearing loss. Otol Neurotol. https://doi.org/10.1097/MAO.0000000000001499CrossRefPubMed

50.

Okumura T, Imai T, Takimoto Y et al (2017) Assessment of endolymphatic hydrops and otolith function in patients with Ménière’s disease. Eur Arch Oto Rhino Laryngol. https://doi.org/10.1007/s00405-016-4418-2CrossRef

51.

Attyé A, Dumas G, Troprès I et al (2015) Recurrent peripheral vestibulopathy: is MRI useful for the diagnosis of endolymphatic hydrops in clinical practice? Eur Radiol. https://doi.org/10.1007/s00330-015-3712-5CrossRefPubMed

52.

Kentala E, Pyykkö I (2001) Clinical picture of vestibular schwannoma. Auris Nasus Larynx. https://doi.org/10.1016/S0385-8146(00)00093-6CrossRefPubMed

53.

Selesnick SH, Jackler RK (1993) The changing clinical presentation of acoustic tumors in the MRI era. Laryngoscope. https://doi.org/10.1002/lary.5541030412CrossRefPubMed

54.

Wiegand DA (1989) Acoustic neuroma — the patient’s perspective: subjective assessment of symptoms, diagnosis, therapy, and outcome in 541 patients. Laryngoscope. https://doi.org/10.1288/00005537-198902000-00010CrossRefPubMed

55.

Mathew GD, Facer GW, Suh KW et al (1978) Symptoms laryngoscope findings, and methods of diagnosis in patients with acoustic. Neuroma. https://doi.org/10.1288/00005537-197812000-00001CrossRef

56.

Van Leeuwen JPPM, Cremers CWRJ, Thewissen NPMW et al (1995) Acoustic neuroma: correlation among tumor size, symptoms, and patient age. Laryngoscope. https://doi.org/10.1288/00005537-199507000-00006CrossRefPubMed

57.

Teggi R, Colombo B, Albera R et al (2018) Clinical features, familial history, and migraine precursors in patients with definite vestibular migraine: the vm-phenotypes projects. Headache. https://doi.org/10.1111/head.13240CrossRefPubMed

58.

Van Esch BF, Van Wensen E, Van Der Zaag-Loonen HJ et al (2017) Clinical characteristics of benign recurrent vestibulopathy: clearly distinctive from vestibular migraine and Menière’s disease? Otol Neurotol. https://doi.org/10.1097/MAO.0000000000001553CrossRefPubMed

59.

Gürkov R, Kantner C, Strupp M et al (2014) Endolymphatic hydrops in patients with vestibular migraine and auditory symptoms. Eur Arch Oto Rhino Laryngol. https://doi.org/10.1007/s00405-013-2751-2CrossRef

60.

Rasmussen BK, Jensen R, Schroll M, Olesen J (1991) Epidemiology of headache in a general population-a prevalence study. J Clin Epidemiol. https://doi.org/10.1016/0895-4356(91)90147-2CrossRefPubMed

61.

Stovner LJ, Hagen K, Jensen R et al (2007) The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. https://doi.org/10.1111/j.14-68-2982.2007.01288.xCrossRefPubMed

62.

Radtke A, Neuhauser H (2009) Prevalence and burden of headache and migraine in Germany. Headache. https://doi.org/10.1111/j.1526-4610.2008.01263.xCrossRefPubMed

63.

Hannaford PC, Simpson JA, Bisset AF et al (2005) The prevalence of ear, nose and throat problems in the community: results from a national cross-sectional postal survey in Scotland. Fam Pract. https://doi.org/10.1093/fampra/cmi004CrossRefPubMed

64.

Cho YS, Choi SH, Park KH et al (2010) Prevalence of otolaryngologic diseases in South Korea: data from the Korea national health and nutrition examination survey 2008. Clin Exp Otorhinolaryngol. https://doi.org/10.3342/ceo.2010.3.4.183CrossRefPubMedPubMedCentral

65.

Neuhauser HK, Radtke A, Von Brevern M et al (2008) Burden of dizziness and vertigo in the community. Arch Intern Med. https://doi.org/10.1001/archinte.168.19.2118CrossRefPubMed

66.

Koo JW, Chang MY, Woo SY et al (2015) Prevalence of vestibular dysfunction and associated factors in South Korea. BMJ Open. https://doi.org/10.1136/bmjopen-2015-008224CrossRefPubMedPubMedCentral

67.

Lin HW, Bhattacharyya N (2014) Impact of dizziness and obesity on the prevalence of falls and fall-related injuries. Laryngoscope. https://doi.org/10.1002/lary.24806CrossRefPubMedPubMedCentral

68.

Agrawal Y, Platz EA, Niparko JK (2008) Prevalence of hearing loss and differences by demographic characteristics among US adults: data from the national health and nutrition examination survey, 1999–2004. Arch Intern Med. https://doi.org/10.1001/archinte.168.14.1522CrossRefPubMed

69.

Golub JS, Lin FR, Lustig LR, Lalwani AK (2018) Prevalence of adult unilateral hearing loss and hearing aid use in the United States. Laryngoscope. https://doi.org/10.1002/lary.27017CrossRefPubMed

70.

Lin FR, Thorpe R, Gordon-Salant S, Ferrucci L (2011) Hearing loss prevalence and risk factors among older adults in the United States. J Gerontol Ser A Biol Sci Med Sci. https://doi.org/10.1093/gerona/glr002CrossRef

71.

Kuttila SJ, Kuttila MH, Niemi PM et al (2001) Secondary otalgia in an adult population. Arch Otolaryngol Head Neck Surg. https://doi.org/10.1001/archotol.127.4.401CrossRefPubMed

72.

Kuttila S, Kuttila M, Le Bell Y et al (1999) Aural symptoms and signs of temporomandibular disorder in association with treatment need and visits to a physician. Laryngoscope. https://doi.org/10.1097/00005537-199910000-00022CrossRefPubMed

73.

Pyakurel M, Bhatta R, Pokharel R (2018) Otorhinolaryngological problem in geriatric population. Nepal J ENT Head Neck Surg. https://doi.org/10.3126/njenthns.v5i2.19423CrossRef

74.

Neuhauser HK, Von Brevern M, Radtke A et al (2005) Epidemiology of vestibular vertigo: a neurotologic survey of the general population. Neurology. https://doi.org/10.1212/01.wnl.0000175987.59991.3dCrossRefPubMed

75.

Vernooij MW, Ikram MA, Tanghe HL et al (2007) Incidental findings on brain MRI in the general population. N Engl J Med. https://doi.org/10.1056/NEJMoa070972CrossRefPubMed

76.

Meyerhoff WL, Kim CS, Paparella MM (1978) Pathology of chronic otitis media. Ann Otol Rhinol Laryngol. https://doi.org/10.1177/000348947808700602CrossRefPubMed

77.

Bisdorff A, Andrée C, Vaillant M, Sándor PS (2010) Headache-associated dizziness in a headache population: prevalence and impact. Cephalalgia. https://doi.org/10.1177/0333102409353617CrossRefPubMed

78.

Chole RA, Parker WS (1992) Tinnitus and vertigo in patients with temporomandibular disorder. Arch Otolaryngol Neck Surg. https://doi.org/10.1001/archotol.1992.01880080039010CrossRef

79.

Cox KW (2008) Temporomandibular disorder and new aural symptoms. Arch Otolaryngol Head Neck Surg. https://doi.org/10.1001/archotol.134.4.389CrossRefPubMed

80.

Jáuregui-Renaud K, Gutierrez-Marquez A, Viveros-Rentería L et al (2013) Neurotology symptoms at referral to vestibular evaluation. J Otolaryngol Head Neck Surg. https://doi.org/10.1186/1916-0216-42-55CrossRefPubMedPubMedCentral

81.

Akhter R, Morita M, Ekuni D et al (2013) Self-reported aural symptoms, headache and temporomandibular disorders in Japanese young adults. BMC Musculoskelet Disord. https://doi.org/10.1186/1471-2474-14-58CrossRefPubMedPubMedCentral

82.

Anderson TD, Loevner LA, Bigelow DC, Mirza N (2000) Prevalence of unsuspected acoustic neuroma found by magnetic resonance imaging. Otolaryngol Neck Surg. https://doi.org/10.1067/mhn.2000.105716CrossRef

83.

Lin D, Hegarty JL, Fischbein NJ, Jackler RK (2005) The prevalence of “incidental” acoustic neuroma. Otolaryngol Head Neck Surg Arch. https://doi.org/10.1001/achotol.131.3.241CrossRef

84.

Conte G, Caschera L, Tuscano B et al (2018) Three-Tesla magnetic resonance imaging of the vestibular endolymphatic space: a systematic qualitative description in healthy ears. Eur J Radiol. https://doi.org/10.1016/j.ejrad.2018.10.023CrossRefPubMed

85.

Bernaerts A, Vanspauwen R, Blaivie C et al (2019) The value of four stage vestibular hydrops grading and asymmetric perilymphatic enhancement in the diagnosis of Menière’s disease on MRI. Neuroradiology. https://doi.org/10.1007/s00234-019-02155-7CrossRefPubMedPubMedCentral

86.

Newman-Toker DE, Cannon LM, Stofferahn ME et al (2007) Imprecision in patient reports of dizziness symptom quality: A cross-sectional study conducted in an acute care setting. Mayo Clin Proc. https://doi.org/10.4065/82.11.1329CrossRefPubMed

87.

Cureoglu S, da Monsanto R, C, Paparella MM, (2016) Histopathology of Meniere’s Disease. Oper Tech Otolaryngol Head Neck Surg. https://doi.org/10.1016/j.otot.2016.10.003CrossRef

88.

Yamashita T, Schuknecht HF (1982) Apical Endolymphatic Hydrops. Arch Otolaryngol. https://doi.org/10.1001/archotol.1982.00790560001001CrossRefPubMed

89.

Gulya AJ, Schuknecht HF (1982) Classification of endolymphatic hydrops. Am J Otolaryngol Neck Med Surg. https://doi.org/10.1016/S0196-0709(82)80003-3CrossRef

90.

Fiorino F, Pizzini FB, Beltramello A, Barbieri F (2011) Progression of endolymphatic hydrops in ménière’s disease as evaluated by magnetic resonance imaging. Otol Neurotol. https://doi.org/10.1097/MAO.0b013e31822a1ce2CrossRefPubMed

91.

Bernaerts A, De Foer B (2019) Imaging of Ménière Disease. N Am Neuroimaging Clin. https://doi.org/10.1016/j.nic.2018.09.002CrossRef

92.

Eliezer M, Gillibert A, Tropres I et al (2017) Influence of inversion time on endolymphatic hydrops evaluation in 3D-FLAIR imaging. J Neuroradiol. https://doi.org/10.1016/j.neurad.2017.06.002CrossRefPubMed

93.

Yazawa Y, Kitahara M (1990) Bilateral endolymphatic hydrops in meniere’s disease: review of temporal bone autopsies. Ann Otol Rhinol Laryngol. https://doi.org/10.1177/000348949009900705CrossRefPubMed

94.

Louza J, Krause E, Gürkov R (2015) Hearing function after intratympanic application of gadolinium-based contrast agent: a long-term evaluation. Laryngoscope. https://doi.org/10.1002/lary.25259CrossRefPubMed

95.

Ohashi T, Naganawa S, Ogawa E et al (2018) Signal intensity of the cerebrospinal fluid after intravenous administration of gadolinium-based contrast agents: strong contrast enhancement around the vein of labbe. Magn Reson Med Sci. https://doi.org/10.2463/mrms.mp.2018-0043CrossRefPubMedPubMedCentral

96.

van den Burg EL, van Hoof M, Postma AA et al (2016) An exploratory study to detect ménière’s disease in conventional MRI scans using radiomics. Front Neurol. https://doi.org/10.3389/fneur.2016.00190CrossRefPubMedPubMedCentral

97.

Lambin P, Rios-Velazquez E, Leijenaar R et al (2012) Radiomics: Extracting more information from medical images using advanced feature analysis. Eur J Cancer. https://doi.org/10.1016/j.ejca.2011.11.036CrossRefPubMedPubMedCentral

98.

Gillies RJ, Kinahan PE, Hricak H (2016) Radiomics: images are more than pictures they are data. Radiology. https://doi.org/10.1148/radiol.2015151169CrossRefPubMedPubMedCentral

Title: The “hype” of hydrops in classifying vestibular disorders: a narrative review
Authors: Marly F. J. A. van der Lubbe
Akshayaa Vaidyanathan
Vincent Van Rompaey
Alida A. Postma
Tjasse D. Bruintjes
Dorien M. Kimenai
Philippe Lambin
Marc van Hoof
Raymond van de Berg
Publication date: 01-12-2020
Publisher: Springer Berlin Heidelberg
Keywords: Vestibular Schwannoma
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Tinnitus
Vestibular Schwannoma
Vestibular Migraine
Published in: Journal of Neurology / Issue Special Issue 1/2020
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-020-10278-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The “hype” of hydrops in classifying vestibular disorders: a narrative review

Abstract

Background

Objective

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Methods

Results

Conclusions

Please log in to get access to this content

Other articles of this Special Issue 1/2020

Vestibular rehabilitation in Europe: a survey of clinical and research practice

Acute consequences of a unilateral VIIIth nerve transection on vestibulo-ocular and optokinetic reflexes in Xenopus laevis tadpoles

Interoception and embodiment in patients with bilateral vestibulopathy

Body-maps of emotions in bilateral vestibulopathy

Simultaneous activation of multiple vestibular pathways upon electrical stimulation of semicircular canal afferents

Computerized clinical decision system and mobile application with expert support to optimize management of vertigo in primary care: study protocol for a pragmatic cluster-randomized controlled trial