Skip to main content
Top
Published in: Lung 3/2021

01-06-2021 | Dyspnea | COVID-19 and COUGH

Prevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study

Authors: César Fernández-de-las-Peñas, Carlos Guijarro, Susana Plaza-Canteli, Valentín Hernández-Barrera, Juan Torres-Macho

Published in: Lung | Issue 3/2021

Login to get access

Abstract

This multicenter study presents prevalence data and associated risk factors of post-COVID-19 cough one year after hospital discharge in COVID-19 survivors. Individuals recovered from COVID-19 at three public hospitals in Madrid (Spain) were scheduled for a telephonic interview. They were systematically asked about the presence of respiratory symptoms, e.g., fatigue, dyspnea, chest pain, and cough after hospital discharge. Clinical and hospitalization data were collected from hospital records. Overall, 1,950 patients (47% women, mean age:61, SD:16 years) were assessed at 11.2 months (SD 0.5) after hospital discharge. Just 367 (18.8%) were completely free of any respiratory post-COVID -19 symptom. The prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively. Clinical and hospitalization factors were not associated with long-term post-COVID-19 cough. In conclusion, the prevalence of post-COVID-19 cough one year after SARS-CoV-2 infection was 2.5% in subjects who had survived hospitalization for COVID-19. No clear risk factor associated to long-term post-COVID-19 cough was identified.
Literature
1.
go back to reference Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W, China Novel Coronavirus Investigating and Research Team (2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 382:727–733CrossRef Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W, China Novel Coronavirus Investigating and Research Team (2020) A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 382:727–733CrossRef
2.
go back to reference Grant MC, Geoghegan L, Arbyn M, Mohammed Z, McGuinness L, Clarke EL, Wade RG (2020) The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): a systematic review and meta-analysis of 148 studies from 9 countries. PLoS One 15:e0234765CrossRef Grant MC, Geoghegan L, Arbyn M, Mohammed Z, McGuinness L, Clarke EL, Wade RG (2020) The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): a systematic review and meta-analysis of 148 studies from 9 countries. PLoS One 15:e0234765CrossRef
3.
go back to reference Alimohamadi Y, Sepandi M, Taghdir M, Hosamirudsari H (2020) Determine the most common clinical symptoms in COVID-19 patients: a systematic review and meta-analysis. J Prev Med Hyg 61:E304PubMedPubMedCentral Alimohamadi Y, Sepandi M, Taghdir M, Hosamirudsari H (2020) Determine the most common clinical symptoms in COVID-19 patients: a systematic review and meta-analysis. J Prev Med Hyg 61:E304PubMedPubMedCentral
4.
go back to reference Dhand R, Li J (2020) Coughs and sneezes: their role in transmission of respiratory viral infections, including SARS-CoV-2. Am J Respir Crit Care Med 202:651–659CrossRef Dhand R, Li J (2020) Coughs and sneezes: their role in transmission of respiratory viral infections, including SARS-CoV-2. Am J Respir Crit Care Med 202:651–659CrossRef
5.
go back to reference Marshall M (2020) The lasting misery of coronavirus long-haulers. Nature 585:339–341CrossRef Marshall M (2020) The lasting misery of coronavirus long-haulers. Nature 585:339–341CrossRef
6.
go back to reference Lopez-Leon, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S (2021) More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv 2021 Jan 1; 2021.01.27.21250617 Lopez-Leon, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, Villapol S (2021) More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv 2021 Jan 1; 2021.01.27.21250617
7.
go back to reference Dicpinigaitis PV, Canning BJ (2020) Is there (will there be) a post-COVID-19 chronic cough? Lung 198:863–865CrossRef Dicpinigaitis PV, Canning BJ (2020) Is there (will there be) a post-COVID-19 chronic cough? Lung 198:863–865CrossRef
8.
go back to reference Cares-Marambio K, Montenegro-Jiménez Y, Torres-Castro R, Vera-Uribe R, Torralba Y, Alsina-Restoy X, Vasconcello-Castillo L, Vilaró J (2021) Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. Chronic Respir Dis 18:14799731211002240CrossRef Cares-Marambio K, Montenegro-Jiménez Y, Torres-Castro R, Vera-Uribe R, Torralba Y, Alsina-Restoy X, Vasconcello-Castillo L, Vilaró J (2021) Prevalence of potential respiratory symptoms in survivors of hospital admission after coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis. Chronic Respir Dis 18:14799731211002240CrossRef
9.
go back to reference Song WJ, Hui CKM, Hull JH, Birring SS, McGarvey L, Mazzone SB, Chung KF (2021) Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses. Lancet Respir Med 9(5):533–544CrossRef Song WJ, Hui CKM, Hull JH, Birring SS, McGarvey L, Mazzone SB, Chung KF (2021) Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses. Lancet Respir Med 9(5):533–544CrossRef
10.
go back to reference Fernández-de-las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, Cuadrado ML, Florencio LL (2021) Defining post-COVID symptoms (post-acute COVID, long COVID, persistent post-COVID): an integrative classification. Int J Environ Res Public Health 18:2621CrossRef Fernández-de-las-Peñas C, Palacios-Ceña D, Gómez-Mayordomo V, Cuadrado ML, Florencio LL (2021) Defining post-COVID symptoms (post-acute COVID, long COVID, persistent post-COVID): an integrative classification. Int J Environ Res Public Health 18:2621CrossRef
Metadata
Title
Prevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study
Authors
César Fernández-de-las-Peñas
Carlos Guijarro
Susana Plaza-Canteli
Valentín Hernández-Barrera
Juan Torres-Macho
Publication date
01-06-2021
Publisher
Springer US
Published in
Lung / Issue 3/2021
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-021-00450-w

Other articles of this Issue 3/2021

Lung 3/2021 Go to the issue