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European Archives of Oto-Rhino-Laryngology

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Open Access 01-06-2010 | Editorial

What is the role of sentinel lymph node biopsy in the management of oral cancer in 2010?

Authors: Francisco J. Civantos, Sandro J. Stoeckli, Robert P. Takes, Julia A. Woolgar, Remco de Bree, Vinidh Paleri, Kenneth O. Devaney, Alessandra Rinaldo, Carl E. Silver, Vanni Mondin, Jochen A. Werner, Alfio Ferlito

Published in: European Archives of Oto-Rhino-Laryngology | Issue 6/2010

Excerpt

Sentinel lymph node biopsy (SLNB) is a minimally invasive technique, performed in conjunction with radiotracer injection and lymphoscintigraphy. This allows the surgeon to identify and excise targeted upper echelon lymph nodes that drain the site of a primary malignancy for the laboratory detection of what would otherwise be subclinical nodal metastases. This technique offers a less invasive means of staging lymphatic basins in a patient with a primary malignancy, and permits detailed histological, immunohistochemical, and molecular examination of at least the first echelon (frequently second and rarely third) lymph node basin for clinically occult micro- and conventional metastases (clinical stage N0). Use of this technique may potentially avoid overtreatment of patients with oral or oropharyngeal squamous cell carcinoma who undergo elective or opportune neck dissection and are subsequently declared pathologically N0, and hence reduce neck dissection-associated morbidity [1]. …

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Title: What is the role of sentinel lymph node biopsy in the management of oral cancer in 2010?
Authors: Francisco J. Civantos
Sandro J. Stoeckli
Robert P. Takes
Julia A. Woolgar
Remco de Bree
Vinidh Paleri
Kenneth O. Devaney
Alessandra Rinaldo
Carl E. Silver
Vanni Mondin
Jochen A. Werner
Alfio Ferlito
Publication date: 01-06-2010
Publisher: Springer-Verlag
Published in: European Archives of Oto-Rhino-Laryngology / Issue 6/2010
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-010-1215-1

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What is the role of sentinel lymph node biopsy in the management of oral cancer in 2010?

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